Patents Assigned to KOHJIN LIFE SCIENCES CO., LTD.
  • Patent number: 10285421
    Abstract: [Problem] To make a color of a processed food containing anthocyanin pigment into a vibrant color. In this respect, using a common foodstuff that is cheap and highly safe, without adding a coloring agent, and not imparting an incongruous flavor to the food is preferred. [Means for Solving the Problem] To an anthocyanin pigment or a common processed food containing anthocyanin pigment is added, in an appropriate amount, a yeast extract containing 5 wt % or more of a peptide, 5 wt % or more of RNA, 4 wt % or less of free amino acid, and preferably further containing 15 wt % or more of dietary fiber.
    Type: Grant
    Filed: July 17, 2013
    Date of Patent: May 14, 2019
    Assignee: KOHJIN LIFE SCIENCES CO., LTD.
    Inventors: Yoshie Yasumatsu, Yuki Saito, Kenichi Ason
  • Publication number: 20190125822
    Abstract: An object of the present invention is to provide a composition for preventing or improving fat deposition on the liver in spite of the alcohol intake history of a level that a liver disease is not caused. The inventors found that glutathione has an effect of preventing or improving fat deposition on the liver, which is not caused by alcohol, and completed the present invention. Among nonalcoholic fat diseases, the present invention is particularly effective in an early stage of the treatment or in a case where treatment for another disease is not performed.
    Type: Application
    Filed: December 26, 2018
    Publication date: May 2, 2019
    Applicants: KOHJIN LIFE SCIENCES CO., LTD., PUBLIC UNIVERSITY CORPORATION YOKOHAMA CITY UNIVERSITY, KYOTO PREFECTURAL PUBLIC UNIVERSITY CORPORATION, SAGA UNIVERSITY
    Inventors: Takaomi KESSOKU, Atsushi NAKAJIMA, Yoshio SUMIDA, Yuichiro EGUCHI, Susumu SAITO, Yusuke SAUCHI
  • Patent number: 10196430
    Abstract: To provide effective use from a yeast extract residue, an excess of which is produced as a byproduct of yeast extract, or reduction in amount of the yeast extract residue. Also to obtain various useful substances. A cell wall lytic enzyme having no protease is allowed to act on a yeast extract residue, after which a heat treatment is performed at 70 to 80° C. for 10 to 20 minutes, thereby enabling separation into a fraction of primarily cell walls and a fraction of primarily protein. A yeast protein having a protein content of 60% or more is obtained from the fraction of primarily protein and, by subjecting the yeast protein to enzymatic degradation, a seasoning having a high amount of total nitrogen is obtained.
    Type: Grant
    Filed: October 31, 2012
    Date of Patent: February 5, 2019
    Assignee: KOHJIN LIFE SCIENCES CO., LTD.
    Inventors: Kenichi Ason, Yusuke Fukuda, Setsuko Hirakura, Hiroko Kodera, Eiji Nakao
  • Publication number: 20180271138
    Abstract: [Problem] To manufacture a foaming member using a low-cost method having little environmental impact, in which the air bubbles in an air-bubble-containing product are enhanced and stability is improved, without imparting viscosity, coloring, flavor, cloudiness, odor, etc. Also, to provide an effective use of yeast cell residue generated as a byproduct of a yeast extract. [Solution] A yeast cell residue remaining after a useful extract is removed from a yeast is suspended in water, and is heated after pH adjustment, and then a supernatant is obtained by centrifugal separation. This fraction contains, in relation to the solid content, 35 wt % or more of protein and 30 wt % or more of dietary fiber, and is usable in the foaming member.
    Type: Application
    Filed: November 9, 2016
    Publication date: September 27, 2018
    Applicant: KOHJIN LIFE SCIENCES CO., LTD.
    Inventors: Eiji NAKAO, Kenichi ASON, Naoto KAJI
  • Patent number: 10023836
    Abstract: In order to provide a culture medium eliminating variation by lot of component concentrations, the present invention provides a culture medium, and preferably a chemical-synthetic culture medium, imparting a proliferation ability to yeast that is equivalent to or greater than that of a YPD culture medium. A culture medium is provided which includes sugars as a carbon source capable of being assimilated by yeast; amino acids as a nitrogen source; vitamins; inositol; zinc ion (Zn2+); potassium ion (K+), and magnesium ion (Mg2+), and in which inositol concentration is between 50 and 10,000 mg/L.
    Type: Grant
    Filed: August 23, 2013
    Date of Patent: July 17, 2018
    Assignees: YAMAGUCHI UNIVERSITY, KOHJIN LIFE SCIENCES CO., LTD.
    Inventor: Rinji Akada
  • Publication number: 20180072634
    Abstract: [Problem] The present invention seeks to provide a composition for plants that is highly safe and that contributes to early harvesting, increasing yield, and increasing added value of crops. Specifically, the present invention provides a yeast extract that, by addition to a foliar surface spray or to soil or water, provides an effect of promoting growth, an effect of root lengthening, an effect of improved taste, and an effect of increased amino acid content of a plant. A substance obtained from yeast that is edible and considered to be safe is preferred as the yeast extract. [Means for Solving the Problem] A yeast extract having a peptide content of 5 wt % or more and an RNA content of 5 wt % or more is sprayed onto or provided as fertilizer to a plant. The yeast extract is preferably derived from Candida utilis, which is edible and considered to be safe.
    Type: Application
    Filed: March 16, 2016
    Publication date: March 15, 2018
    Applicant: KOHJIN LIFE SCIENCES CO., LTD.
    Inventors: Tomohiro NAKAGAWA, Yoshie YASUMATSU, Naoto KAJI, Kenichi ASON
  • Publication number: 20180050078
    Abstract: An object of the present invention is to provide a composition for preventing or improving fat deposition on the liver in spite of the alcohol intake history of a level that a liver disease is not caused. The inventors found that glutathione has an effect of preventing or improving fat deposition on the liver, which is not caused by alcohol, and completed the present invention. Among nonalcoholic fat diseases, the present invention is particularly effective in an early stage of the treatment or in a case where treatment for another disease is not performed.
    Type: Application
    Filed: March 2, 2016
    Publication date: February 22, 2018
    Applicants: KOHJIN LIFE SCIENCES CO., LTD., PUBLIC UNIVERSITY CORPORATION YOKOHAMA CITY UNIVERSITY, KYOTO PREFECTURAL PUBLIC UNIVERSITY CORPORATION, SAGA UNIVERSITY
    Inventors: Takaomi KESSOKU, Atsushi NAKAJIMA, Yoshio SUMIDA, Yuichiro EGUCHI, Susumu SAITO, Yusuke SAUCHI
  • Patent number: 9885005
    Abstract: [Problem] To provide a phospholipid ?-linolenic acid composition of consistent quality and having a stable supply of source material, with focus on Torula yeast, which is edible and recognized as safe, in order to resolve issues with omega 3 sources. [Means for Solving the Problem] As a result of intensive study to resolve the above-noted issues, the inventors of the present invention have discovered that a phospholipid ?-linolenic acid composition can be obtained using residue of yeast extract extracted from Torula yeast (Candida utilis), for example, which is currently produced in large quantities for application in foods, and so arrived at the present invention.
    Type: Grant
    Filed: March 9, 2015
    Date of Patent: February 6, 2018
    Assignees: KOHJIN LIFE SCIENCES CO., LTD., HIROSAKI UNIVERSITY
    Inventors: Naoto Kaji, Shiroh Aida, Katsuhiro Osaki, Masato Omae, Tomohiro Nakagawa, Motoyuki Tokuriki, Hayato Maeda
  • Publication number: 20170258097
    Abstract: [Problem] To produce a frozen bread dough improver that has an effect of improving rising of frozen bread dough, is highly safe, and tasteless, using a method that is low-cost and low in environmental impact. Also, to effectively use yeast cell body residue produced as a byproduct of yeast extract. [Means for Solving the Problem] Yeast cell body residue remaining after extracting useful extract from yeast is suspended in water and heated, after which the suspension is subjected to centrifugal separation and a supernatant is obtained. This fraction contains, per solid content, at least 45 wt % RNA, at least 5 wt % dietary fiber, and at least 10 wt % protein, and mannan content in the dietary fiber is at least 60 wt %. This can be used to improve rising of frozen bread dough.
    Type: Application
    Filed: August 28, 2015
    Publication date: September 14, 2017
    Applicants: KOHJIN LIFE SCIENCES CO., LTD., THE SCHOOL CORPORATION KANSAI UNIVERSITY
    Inventors: Hidehisa KAWAHARA, Eiji NAKAO, Kenichi ASON, Sakiko IKEDA
  • Publication number: 20170224790
    Abstract: The present invention features compositions that include a fungal glucosylceramide (GlcCer) purified from a non-pathogenic fungus (e.g., Candida utilis) and, optionally, an adjuvant. The invention also features methods of treating a patient who has a fungal disease and methods of preventing a fungal disease in a subject by administration of these compositions. Also within the scope of the invention are methods of formulating a fungal vaccine by: (a) providing a fungal glucosylceramide isolated from a non-pathogenic fungus; and (b) combining the fungal glucosylceramide with an adjuvant in a physiologically acceptable excipient.
    Type: Application
    Filed: September 30, 2015
    Publication date: August 10, 2017
    Applicants: KOHJIN LIFE SCIENCES CO., LTD., THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK
    Inventors: Maurizio DEL POETA, Visesato MOR, Toshiya SATO, Tomohiro NAKAGAWA
  • Publication number: 20170196235
    Abstract: [Problem] To produce, with a method that is low-cost and has a low environmental impact, a cloudiness-inhibiting agent that is highly safe and has no taste which has a cloudiness-inhibiting effect in a tea beverage. Also, to make effective use of yeast cell body residue produced as a byproduct of yeast extract. [Means for Solving the Problem] Yeast cell body residue remaining after removing useful extract from yeast is suspended in water and heated, after which the suspension is subjected to centrifugation to obtain a supernatant. This fraction has an amount of RNA content per solid content of the yeast extract of at least 50 wt %, dietary fiber content of at least 5 wt %, and protein content of at least 10 wt %. Mannan content is at least 60 wt % of the dietary fiber. This fraction can be used to inhibit cloudiness for a tea beverage.
    Type: Application
    Filed: July 15, 2015
    Publication date: July 13, 2017
    Applicant: KOHJIN LIFE SCIENCES CO., LTD.
    Inventors: Eiji NAKAO, Yoshie YASUMATSU, Kenichi ASON
  • Publication number: 20170081610
    Abstract: [Problem] To provide a phospholipid ?-linolenic acid composition of consistent quality and having a stable supply of source material, with focus on Torula yeast, which is edible and recognized as safe, in order to resolve issues with omega 3 sources. [Means for Solving the Problem] As a result of intensive study to resolve the above-noted issues, the inventors of the present invention have discovered that a phospholipid ?-linolenic acid composition can be obtained using residue of yeast extract extracted from Torula yeast (Candida utilis), for example, which is currently produced in large quantities for application in foods, and so arrived at the present invention.
    Type: Application
    Filed: March 9, 2015
    Publication date: March 23, 2017
    Applicants: KOHJIN LIFE SCIENCES CO., LTD., KOHJIN LIFE SCIENCES CO., LTD., HIROSAKI UNIVERSITY, HIROSAKI UNIVERSITY
    Inventors: Naoto KAJI, Shiroh AIDA, Katsuhiro OSAKI, Masato OMAE, Tomohiro NAKAGAWA, Motoyuki TOKURIKI, Hayato MAEDA
  • Publication number: 20170042201
    Abstract: An antiflocculation/settling agent is manufactured with a method having a low cost and low environmental impact, the agent having a high level of safety and no taste, and having an inhibitory effect on flocculation/settling of a food or beverage. Also, to make effective use of yeast cell body residue produced as a byproduct of yeast extract. Yeast cell body residue remaining after removal of useful extract from yeast is suspended in water and heated, after which the suspension is subjected to centrifugal separation and supernatant is collected. This fraction contains at least 15 wt % RNA content per solid content, at least 10 wt % dietary fiber content, and at least 15 wt % protein content, and mannan makes up at least 50 wt % of the dietary fiber. This fraction can be used as an antiflocculation/settling agent in foods and beverages.
    Type: Application
    Filed: May 7, 2015
    Publication date: February 16, 2017
    Applicant: KOHJIN LIFE SCIENCES CO., LTD.
    Inventors: Eiji NAKAO, Yoshie YASUMATSU, Kenichi ASON
  • Publication number: 20160158309
    Abstract: The inventors of the present invention have discovered that glutathione inhibits reduction in muscle pH, and activates PGC-1? to increase production of mitochondrial DNA. The present invention has been completed based on these findings.
    Type: Application
    Filed: December 11, 2015
    Publication date: June 9, 2016
    Applicants: KYOTO PREFECTURAL PUBLIC UNIVERSITY CORPORATION, KOHJIN LIFE SCIENCES CO., LTD.
    Inventors: Wataru AOI, Toru KONISHI, Yusuke SAUCHI
  • Publication number: 20150299647
    Abstract: In order to provide a culture medium eliminating variation by lot of component concentrations, the present invention provides a culture medium, and preferably a chemical-synthetic culture medium, imparting a proliferation ability to yeast that is equivalent to or greater than that of a YPD culture medium. A culture medium is provided which includes sugars as a carbon source capable of being assimilated by yeast; amino acids as a nitrogen source; vitamins; inositol; zinc ion (Zn2+); potassium ion (K+), and magnesium ion (Mg2+), and in which inositol concentration is between 50 and 10,000 mg/L.
    Type: Application
    Filed: August 23, 2013
    Publication date: October 22, 2015
    Applicants: YAMAGUCHI UNIVERSITY, KOHJIN LIFE SCIENCES CO., LTD.
    Inventor: Rinji AKADA
  • Publication number: 20150164120
    Abstract: [Problem] To make a color of a processed food containing anthocyanin pigment into a vibrant color. In this respect, using a common foodstuff that is cheap and highly safe, without adding a coloring agent, and not imparting an incongruous flavor to the food is preferred. [Means for Solving the Problem] To an anthocyanin pigment or a common processed food containing anthocyanin pigment is added, in an appropriate amount, a yeast extract containing 5 wt % or more of a peptide, 5 wt % or more of RNA, 4 wt % or less of free amino acid, and preferably further containing 15 wt % or more of dietary fiber.
    Type: Application
    Filed: July 17, 2013
    Publication date: June 18, 2015
    Applicant: KOHJIN LIFE SCIENCES CO., LTD.
    Inventors: Yoshie Yasumatsu, Yuki Saito, Kenichi Ason
  • Publication number: 20140234526
    Abstract: The present invention addresses enhancing a taste of common processed food and drink without imparting a foreign taste and without increasing calories or sodium content. In such a case, a substance added to the common processed food and drink is preferably a common foodstuff, and preferably has a high degree of safety. A yeast extract having a peptide content of 5 wt % or more, an RNA content of 5 wt % or more, a free amino acid content of 4 wt % or less, and more preferably having a dietary fiber content of 15 wt % or more is added in an appropriate amount to the common processed food and drink.
    Type: Application
    Filed: August 21, 2012
    Publication date: August 21, 2014
    Applicant: KOHJIN LIFE SCIENCES CO., LTD.
    Inventors: Yoshie Yasumatsu, Hiroko Kodera, Kenichi Ason
  • Publication number: 20140228305
    Abstract: To produce a glucosylceramide composition suitable for a functional food or a medicinal product, having stable quality, and cleared of contaminants such as sterol glycosides. An objective is to produce a glucosylceramide composition at low cost from a raw material which is safe, has been eaten by human beings, and is readily available. A glucosylceramide-containing composition is produced by extraction from a raw material of a yeast residue in an organic solvent, such as an alcohol, the yeast residue being obtained after extraction of yeast extract from Torula yeast or the like.
    Type: Application
    Filed: April 24, 2012
    Publication date: August 14, 2014
    Applicant: KOHJIN LIFE SCIENCES CO., LTD.
    Inventors: Toshiya Sato, Tomohiro Nakagawa, Naoto Kaji