Abstract: An auxiliary agent for ophthalmic surgery is based on collagen and, after the completion of surgery, undergoes a lowering in viscosity, and thus can be easily removed. This agent is a neutral solution of collagen which is transparent at a neutral pH and has a denaturation temperature below the intraocular temperature, or a derivative thereof. The agent has a visual light transmission at 400 nm of at least 90% of that before the denaturation, when solution is heated to cause denaturation.
Type:
Grant
Filed:
April 16, 1999
Date of Patent:
January 23, 2001
Assignees:
Koken Co Ltd, Japan Science & Technology Corporation