Patents Assigned to Kokichi Kikuchi
  • Publication number: 20050208064
    Abstract: A peptide that induces CTL against human gastric cancer cells is provided. A peptide having a specific amino-acid sequence and induces cytotoxic T cells that targets gastric cancer cells may be used as an agent for preventing or treating gastric cancer.
    Type: Application
    Filed: February 7, 2005
    Publication date: September 22, 2005
    Applicants: Ajinomoto Co., Inc., Kokichi Kikuchi
    Inventors: Kokichi Kikuchi, Noriyuki Sato, Hiromitsu Sahara, Takahiro Yasojima, Yoshimasa Wada, Manabu Suzuki, Junji Hamuro
  • Patent number: 6444800
    Abstract: A tumor antigen gene is identified by screening a cDNA library derived from a gastric cancer cell line that can induce gastric cancer antigen specific cytotoxic T cell (CTL) by means of hybridization and PCR utilizing an amino acid sequence of peptide fragment of a known gastric cancer antigen protein, introducing a selected cDNA clone into a cell of gastric cancer cell line that cannot induce gastric cancer antigen specific CTL so that the clone should be expressed in the cell, and selecting a transgenic cell that has acquired the ability to induce CTL. According to the present invention, there are provided a protein capable of inducing immune response against human gastric cancer, DNA encoding the protein, as well as vaccine for treatment and prevention of human gastric cancer, and agent for treatment and prevention of human gastric cancer.
    Type: Grant
    Filed: July 7, 1999
    Date of Patent: September 3, 2002
    Assignees: Ajinomoto Co., Inc., Kokichi Kikuchi
    Inventors: Kokichi Kikuchi, Noriyuki Sato, Toshihiko Torigoe, Hiroeki Sahara, Manabu Suzuki, Junji Hamuro
  • Patent number: 5837248
    Abstract: A peptide that induces CTL against human gastric cancer cells is provided. A peptide having a specific amino-acid sequence and induces cytotoxic T cells that targets gastric cancer cells may be used as an agent for preventing or treating gastric cancer.
    Type: Grant
    Filed: September 30, 1996
    Date of Patent: November 17, 1998
    Assignees: Ajinomoto Co., Inc., Kokichi Kikuchi
    Inventors: Kokichi Kikuchi, Noriyuki Sato, Hiromitsu Sahara, Takahiro Yasojima, Yoshimasa Wada, Manabu Suzuki, Junji Hamuro