Abstract: A biological substance detection method for detecting a biological substance specifically in a pathological specimen, comprising a step of immunologically staining the pathological specimen using a fluorescent label, a step of staining the pathological specimen with a staining reagent for morphology observation purposes (eosin) to observe the morphology of the pathological specimen, a step of irradiating the stained pathological specimen with excited light to cause the emission of a fluorescent and detecting the biological substance in the pathological specimen. In the step of immunologically staining the pathological specimen, a special fluorescent particle for which the excitation wavelength appears in a region that is different from the excitation wavelength region of eosin is used as the fluorescent label.
August 30, 2011
Date of Patent:
May 22, 2018
KONICA MINOLTA MEDICAL & GRAPHIC, INC., KONICA MINOLTA, INC.
Abstract: An ultrasound diagnostic device includes: an ultrasound probe which transmits ultrasound toward a tested subject by a plurality of transducers and obtains a received signal; a beam forming section for adding the received signal for each of the transducers with matching a phase of the received signal; an image processing section which generates an image data; a coherent factor calculation section which calculates a coherent factor which represents a ratio of a coherent sum to an incoherent sum; a coherent factor correction section which corrects the coherent factor so as not to be smaller than a predetermined value; and a signal correction section which correct the received signal after having been subject to the adding, by multiplying the received signal after having been subject to the adding by the coherent factor corrected by the coherent factor correction section as a coefficient.
Abstract: An ultrasound probe includes a piezoelectric section to transmit and receive ultrasound, wherein the piezoelectric section includes a plurality of laminated piezoelectric layers each of which includes piezoelectric members and non-piezoelectric members both of which are arranged alternately in parallel to each other in an arrangement direction, and wherein the arrangement direction of the piezoelectric members and the non-piezoelectric members in at least one piezoelectric layer of the plurality of laminated piezoelectric layers is different from that in other one piezoelectric layer of the plurality of laminated piezoelectric layers.
Abstract: An ultrasound diagnostic equipment is equipped with an ultrasound probe which transmits an ultrasound wave toward an inner part of a subject and receives the ultrasound wave reflected with a particle body in the subject and acquires a received signal to displays internal body information in the subject based on the received signal. The ultrasound diagnostic equipment includes: an acquisition section to acquire the received signal for each of ultrasound waves of which frequencies differ; an intensity ratio calculation section to calculate an intensity ratio of the ultrasound wave for each of frequencies; and a display section to display the information on the intensity ratio.
Abstract: In an ultrasonic diagnostic device S according to the present invention, a reference signal generation unit 30 generates a reference signal to be used in correlation processing based on a direct reception signal obtained by receiving a first ultrasonic signal prior to being transmitted to a subject. Consequently, the ultrasonic diagnostic device S configured in this manner is able to generate a more suitable reference signal.
Abstract: Disclosed is an ultrasound diagnostic imaging apparatus including an ultrasound probe which outputs a transmission ultrasound wave toward a subject due to a driving signal and which outputs a received signal by receiving a reflection ultrasound wave from the subject, a transmitting unit which makes the ultrasound probe generate the transmission ultrasound wave by outputting each of a first transmission signal, a second transmission signal, a third transmission signal and a fourth transmission signal as the driving signal, and a signal component extraction unit which extracts a higher harmonic component and a difference frequency component by compounding a first received signal, a second received signal, a third received signal and a fourth received signal.
Abstract: In a laminated piezoelectric body, a laminated piezoelectric body manufacturing method, an ultrasound transducer, and an ultrasound diagnostic device according to the present invention, a plurality of mutually laminated piezoelectric bodies are electrically connected in parallel to each other, and each of the plurality of piezoelectric bodies arranges an orientation of residual polarization or a crystal axis that is related to an electrical displacement or a sign of an electric field due to a direct piezoelectric effect in a direction which reduces sensitivity in a first resonance mode and increases sensitivity in a second resonance mode of a higher order than the first resonance mode with respect to an axis of a first-level piezoelectric body on a fixed end-side.
Abstract: Disclosed is an ultrasound diagnostic imaging apparatus including an ultrasound probe which outputs a transmission ultrasound toward a subject and a received signal obtained by receiving a reflected ultrasound from the subject, a transmission unit, a receiving unit and a puncture needle position detection unit which obtains a puncture needle echo information indicating an angle and a position of the puncture needle from the plane-wave received signal, and an ultrasound image is displayed on the basis of the received signal, the transmission unit applies the driving signal to the ultrasound probe so that a plane-wave transmission ultrasound is output from the ultrasound probe, and the receiving unit receives a plane-wave received signal which is obtained in such a way that the plane-wave transmission ultrasound is transmitted from the ultrasound probe, reflected by a puncture needle to be the reflected ultrasound and received by the ultrasound probe.
Abstract: The present invention provides a production method of a radiation image detector, comprising a scintillator panel preparation step, a composite rigid plate preparation step of bonding a flexible polymer film to a rigid plate with an adhesive to prepare the composite rigid plate, a preparation step of a scintillator panel provided with a composite rigid plate of bonding the composite rigid plate to a scintillator panel to prepare the scintillator panel provided with a composite rigid plate, and a preparation step of a radiation image detection member of opposing the surface of the photoelectric conversion base plate in which the photoelectric conversion elements are disposed to the surface of the side of the scintillator layer of the scintillator panel provided with the composite rigid plate and bonding the photoelectric conversion base plate to the scintillator panel to prepare a radiation image detection member; whereby there are provided a production method of a radiation image detector which can be easily
Abstract: Disclosed is an ultrasound diagnostic imaging apparatus including an ultrasound probe which outputs transmission ultrasound waves toward a subject by a driving signal and which outputs received signals by receiving reflection ultrasound waves from the subject and a transmitting unit which generates the transmission ultrasound waves by the ultrasound probe by outputting the driving signal, and the transmitting unit generates the driving signal of square wave having a waveform in which a standard pulse signal where a pulse cycle is 2 T is combined with two first pulse signals of same polarity having a pulse width A (A<T) and a second pulse signal having a pulse width B (B=T?2A), the second pulse signal having a polarity different from the polarity of the first pulse signals.
November 9, 2012
Date of Patent:
December 15, 2015
KONICA MINOLTA MEDICAL & GRAPHIC, INC.
Daisuke Kaji, Yoshihiro Takeda, Kazuya Osada
Abstract: The steps of the method to make the scintillator panel are providing a first support having thereon a phosphor layer; dividing the first support the phosphor layer into a plurality of scintillator panel sections each having a first support section and a phosphor layer section thereon; providing an adhesive member between a side of the first support section of each of the plurality of the scintillator panel sections and a side of a second support; adhering the plurality of the scintillator panel sections onto the second support; forming a protective layer on a whole surface of the plurality of the scintillator panel sections except a portion of the scintillator panel sections which is contacted with the adhesive member; and separating the scintillator panel sections with their protective layer thereon from the second support. The separated scintillator panel sections with their protective layer are then adhered to light receiving element to form the flat panel detector.
Abstract: The present invention aims to provide a technique enabling an information added by another user to be referenced and enabling the range of the information the user references from a database to be customized. A related information database in which a plurality of elements are accumulated is prepared, and an output setting information in which an information relating to the output of an additional information is associated with each other, in response to the additional writing of the additional information by a certain user to the related information database is stored. The output setting information of the certain user can be changed by the user. A portion of information is extracted from the related information database in accordance with an input of an extraction condition by the user, and the portion of information is visually output according to information relating to the output of the user.
Abstract: Disclosed is a scintillator panel provided with on a support a phosphor layer comprising columnar crystals and a protective layer sequentially in this order, wherein degraded areas on lateral surfaces of columnar crystals at an end of the phosphor layer and produced by a cutting treatment account for not less than 0% and not more than 40% of an area of all of the side surfaces of the columnar crystals. A production method of the scintillator panel is also disclosed.
Abstract: A radiation image imaging apparatus includes: a sensor board in which a plurality of photoelectric conversion elements are arranged two-dimensionally; and a scintillator which converts an incident radiation into light and irradiates the light onto the photoelectric conversion elements, and a protection layer having an anti-static function is provided between the sensor board and the scintillator, and an anti-static layer having conductivity or an anti-static function is provided on a surface of the sensor board, the surface being opposite with a side facing the scintillator.
Abstract: The apparatus includes: an X-ray source a multi slits element a first grating; a second grating; a driving section; a subject placing plate: and an X-ray detector, in which conversion elements to convert intensities of X-rays received thereby to electric signals, are arranged in a two-dimensional pattern so as to read the electric signals as image signals. The driving section moves the multi slits element relative to both the first grating and the second grating in a first direction orthogonal to a second direction of irradiating the X-rays, so that the X-ray detector repeats a processing for reading the electric signals converted from the intensities of X-rays received thereby, every time when the multi slits element moves at predetermined intervals so as to acquire the image signals representing Moire images captured at the predetermined intervals.
Abstract: A control device of a radiation image capturing apparatus performs repeated reading of leak data prior to radiation image capturing operation and, when a threshold value has been exceeded by the leak data having been read out, said control device detects the start of irradiation. If there are periodic fluctuations in the leak data read out prior to radiation image capturing operation even though irradiation has not started, said control device determines whether or not a threshold value has been exceeded by a value obtained by subtracting a previously obtained fluctuation pattern of the leak data from the read-out leak data during a time period including at least a time period when the leak data fluctuates.
Abstract: Disclosed is a quantum dot-embedded silica nanoparticle having plural quantum dots embedded within the silica nanoparticle, wherein the number of quantum dots existing in a concentric area within 10% of a radius from a center of the silica nanoparticle accounts for 10 to 70% of the number of total quantum dots embedded in the silica nanoparticle.
Abstract: The present invention provides a method for displaying medical images and a medical image display system that do not require a medical practitioner to move his/her line of sight at the time of comparing/interpreting images and that can improve accuracy in diagnosis. According to the medical image display system of the present invention: an X-ray imaging device captures an image of a subject according to a first imaging mode by a fringe-scanning imaging device or a second imaging mode by a Fourier transform imaging device; a controller creates at least two images from among an X-ray absorption image, a differential phase image, and a small-angle scattering image on the basis of the captured moir image; and said at least two images that have been created are displayed in turn in the same position on a display section.
Abstract: Disclosed in an x-ray imaging device, which uses a Talbot-Lau interferometer, eliminates the effects on image quality of a reconstructed image that arises in such cases as when the direction of a multi-slit or each lattice slit is altered and imaging is performed, and provides reconstructed images favorable for diagnosis. When a plurality of moire images imaged with an imaging subject loaded onto a imaging subject stand (13) and a plurality of moire images imaged without the imaging subject are input, a control unit (51) of a controller (5) corrects signal value differences arising from variations in x-ray strength during imaging respectively between the plurality of moire images with the imaging subject and between the plurality of moire images without the imaging subject, and respectively creates a reconstructed image with the imaging subject and a reconstructed image without the imaging subject.
Abstract: In the present invention, provided is an organic piezoelectric material specifically exhibiting high orientation and thermal stability as an organic piezoelectric material exhibiting an excellent piezoelectric characteristic and having piezoelectricity and pyroelectricity, which is capable of converting thermal or mechanical simulation into electrical energy, and also provided are an ultrasound probe for which the organic piezoelectric material is used, and an ultrasound image detector thereof. It is a feature that an organic piezoelectric material of the present invention possesses a compound represented by Formula (1) and a base material made of an organic polymeric material, satisfying Expression (1): |C Log P (1)?C Log P (base material)|?3.0 when C Log P values of the compound and the base material are expressed as C Log P (1) and C Log P (base material), respectively.