Abstract: A nonameric peptide represented by an amino acid sequence of SEQ ID NO: 1 or its enantiomeric peptide thereof according to the present invention is low in cytotoxicity and excellent in terms of proteolytic stability, antimicrobial activity, and anti-inflammatory activity and has a remarkable therapeutic effect on Gram-negative bacterial infectious diseases, sepsis, or septic shock. Accordingly, the peptides can be advantageously applied to an antimicrobial composition, an anti-inflammatory composition, and a pharmaceutical composition for prevention or treatment of Gram-negative bacterial infectious diseases, sepsis, or septic shock.

Abstract: A display apparatus includes a display panel, a driving controller and a data driver. The display panel displays an image based on input image data. The driving controller generates a data signal based on the input image data, determines an optical flow based on previous frame data of the input image data and present frame data of the input image data and determines a user's self-motion using the optical flow. The data driver converts the data signal to a data voltage and outputs the data voltage to the display panel.

Abstract: A simultaneous implementation method of 3D subtraction magnetic resonance (MR) arteriography, 3D subtraction MR venography, and color-coded 4D MR angiography through post-processing of image information of 4D MR angiography according to an embodiment of the present disclosure may reduce scan time required to individually obtain an MR arteriography and an MR venography. In addition, not only anatomical information of arteries but also more accurate anatomical information of veins and more detailed hemodynamic information may be obtained.

Abstract: The present invention relates to a fire-extinguishing microcapsule, a method for manufacturing same, and a fire-extinguishing composition comprising same. The microcapsule includes a core containing a non-inflammable material; a first shell layer covering the core and containing inorganic nanoparticles and a water-soluble polymer; and a second shell layer covering the first shell layer and containing a polymer.

Abstract: An apparatus and method for estimating a vehicle pitch relative to a road. The apparatus includes a wheel speed sensor part which obtains wheel speed data, an inertial measurement unit (IMU) sensor part which obtains IMU data, a preprocessing part which extracts a stop section and a moving section on the basis of the wheel speed data and the IMU data, and a slope estimation part which estimates a vehicle pitch in the stop section and a road slope in the moving section and estimates a vehicle pitch relative to a road on the basis of the vehicle pitch and the road slope.

Abstract: A learning method for generating a multiphase collateral image comprises the steps of: receiving inputs of an MRI image of a head part and a multiphase collateral image generated on the basis of the MRI image; generating a brain mask by using the MRI image; generating an MRI image and a multiphase collateral image which are masked by the brain mask; and learning the masked multiphase collateral image for the masked MRI image by using a learning network.

Abstract: The present invention relates to a method of inhibiting, delaying, or reversing cellular senescence that includes having an isolated cell flow through a microchannel, and crashing the cell in flow into an impact surface installed on a flow path of the cell to apply a physical impact to the cell, resulting in inhibiting, delaying, or reversing senescence of the cell, while maintaining high biological activity, and in particular, it relates to a method that can further increase the value of a stem cell as a therapeutic cell for various degenerative diseases by maintaining undifferentiated state of the stem cell even during a long-term culture period to maintain multipotency, and to the cells obtained by the method.

Abstract: Proposed are a method of preparing a metal nanostructure, which includes (a) preparing a first metal template whose surface is coated with a polymeric micelle containing an amphiphilic polymer and (b) causing the first metal template to react with a second metal ion through a galvanic replacement reaction, and a metal nanostructure prepared thereby. The amphiphilic polymer is used as a capping agent during the replacement reaction so that the micellar polymer is adsorbed onto the template, thereby selectively allowing the replacement reaction. Thus, unlike in existing technologies in which nanostructures having limited forms are prepared, nanostructures having a new two-dimensional structure, including nanostructures having a plurality of pores formed between nanoparticles, can be prepared.

Abstract: The present invention is to provide multilayered multiple quantum dot-doped nanoparticles, each of the multiple quantum dot-doped nanoparticles has a structure consisting of an inorganic core particle, a quantum dot-embedded layer, and a silica/quantum dot composite shell. The multiple quantum dot-doped nanoparticles can be used to detect biomolecules with improved quantum yield (QY) and brightness while maintaining a large area covered by the quantum dots and stable bonds of the quantum dots. Therefore, the multiple quantum dot-doped nanoparticles are suitable for bioapplications, including bioplatforms and highly sensitive methods for detecting biomolecules.

Abstract: The present disclosure relates to a system for measuring changes in the vital signs of poultry and a method for predicting whether poultry is infected with pathogens using the same. The present disclosure can be helpfully used to determine an overall health condition including the outbreak of various poultry diseases by measuring quantitative changes in vital signs of poultry in real time. In particular, the present disclosure provides reliable real-time information about changes in vital signs through comparison of body temperature and noise measurement values of poultry for each time period reflecting circadian changes of the poultry, rather than simple comparison of the body temperature and noise measurement values with simple reference values, and thus can be used for early diagnosis of highly infectious pathogens such as avian influenza virus and early isolation of confirmed cases, and ultimately for effective prevention of the spread of diseases.

Abstract: An apparatus and method for estimating a vehicle pitch relative to a road. The apparatus includes a wheel speed sensor part which obtains wheel speed data, an inertial measurement unit (IMU) sensor part which obtains IMU data, a preprocessing part which extracts a stop section and a moving section on the basis of the wheel speed data and the IMU data, and a slope estimation part which estimates a vehicle pitch in the stop section and a road slope in the moving section and estimates a vehicle pitch relative to a road on the basis of the vehicle pitch and the road slope.

Abstract: Provided is a pharmaceutical composition including an Abeliophyllum distichum extract as an active ingredient for treating androgen receptor-related diseases. The Abeliophyllum distichum extract according to the presently claimed subject matter or isoquercetin has an inhibitory activity against the androgen receptor and an excellent therapeutic effect on benign prostatic hyperlasia animal models, thus this finding can apply widely to the industry for relevant therapeutic agents for androgen receptor-related diseases such as benign prostatic hyperplasia, androgen-dependent hair loss, dysuria, and prostate cancer.

Abstract: The present disclosure relates to a method for producing mesenchymal stem cells from pluripotent stem cells and mesenchymal stem cells prepared by the method. The present disclosure enables mesenchymal stem cells having superior proliferation rate while having superior intrinsic biological activity to be obtained with high yield by sequentially performing three-dimensional suspension culture using pluripotent stem cells, particularly induced pluripotent stem cells (iPSCs), as starting cells and adherent culture of cell aggregates formed therethrough. The mesenchymal stem cells produced by the method of the present disclosure can be usefully used in compositions for treating bone diseases, cartilage diseases or inflammatory and autoimmune diseases owing to high differentiation efficiency into bone and cartilage and superior anti-inflammatory activity.

Abstract: The present invention relates to an extinguishing composition and comprises an extinguishing material and a capsule containing the extinguishing material, and the extinguishing material comprises calcium bromide (CaBr2).

Abstract: The present disclosure relates to a method for producing extracellular vesicles from three-dimensionally cultured stem cells. The method of the present disclosure can produce stem cell-derived extracellular vesicles with a high yield through orbital shaking culture of stem cell aggregates in the presence of TGF-? and thus can be usefully used in an industrial-scale mass production process of exosomes that can be utilized as a pharmaceutical ingredient substituting for a cell therapeutic agent. Furthermore, the exosomes obtained by the method of the present disclosure have significantly improved immunoregulatory functions as compared to the exosomes produced by the existing method and, therefore, can be applied as a superior therapeutic composition for various inflammations or autoimmune diseases.

Abstract: In the present invention, among blood metabolites, amino acids, organic compounds and oxylipins that were statistically significantly differentiated from the control group, were selected from type 2 diabetes patients. Specifically, asparagine, aspartic acid, glutamic acid, cysteine, lysine, citric acid, and uric acid, and 12-oxo ETE, 15-oxo ETE, 9-oxo ODE, and 20-carboxy leukotriene B4, which are oxylipins, were confirmed to have cutoff values of AUC>0.7. In addition, the blood metabolites showed a significant difference between a DME patient group and a non-DME patient group, and thus were confirmed to be usable for accurate diagnosis of DME.

Abstract: The present invention relates to an influenza virus surface protein-derived recombinant hemagglutinin (HA) protein forming a trimer and use thereof, and more specifically to a recombinant vector for producing an influenza virus surface protein-derived HA protein forming a trimer, a transformant transformed by the recombinant vector, a method for producing an influenza virus surface protein-derived HA protein forming a trimer using the recombinant vector, an influenza virus surface protein-derived HA protein produced by the method, and the use thereof in preventing, ameliorating or treating influenza virus-infected disease.

Abstract: A scan driver includes stage circuits, wherein each of the stage circuits includes a first transistor, wherein a first electrode thereof is coupled to a first node, a second electrode thereof is coupled to an input carry line, and a gate electrode thereof is coupled to a first clock line; and a capacitor, wherein a first electrode thereof is coupled to the first node and a second electrode thereof is coupled to a second node, wherein the second node is coupled to an output carry line, and the second node is selectively coupled to one of a first power voltage line and a second power voltage line.

Abstract: Disclosed are a method and apparatus for self-training of machine reading comprehension to improve domain adaptation. The method for self-training of the machine reading comprehension may include generating a pseudo training data set comprising pseudo-questions and pseudo-answers in response to a change in a domain to which a trained machine reading comprehension model is to be applied, refining the pseudo training data set, and retraining the machine reading comprehension model and a pseudo-question generator that generates the pseudo-questions using the refined pseudo training data set.

Abstract: Disclosed herein is a method for compressing an image for machine vision, the method including detecting objects in an input image using an object detection network, generating a foreground image including bounding boxes corresponding to the objects and a background image, which is an image acquired by excluding the bounding boxes from the input image, encoding the foreground image and the background image, and decoding the encoded foreground image and the encoded background image.