Abstract: Provided is a pharmaceutical composition including an Abeliophyllum distichum extract as an active ingredient for treating androgen receptor-related diseases. The Abeliophyllum distichum extract according to the presently claimed subject matter or isoquercetin has an inhibitory activity against the androgen receptor and an excellent therapeutic effect on benign prostatic hyperlasia animal models, thus this finding can apply widely to the industry for relevant therapeutic agents for androgen receptor-related diseases such as benign prostatic hyperplasia, androgen-dependent hair loss, dysuria, and prostate cancer.

Abstract: The present disclosure relates to a composition containing extracellular vesicles isolated from skeletal muscle-derived stem cells as active ingredients, which exhibits the effect of skin aging delay, wound healing, scar reduction and skin whitening, thereby improving skin condition. The present disclosure can not only utilize tissues wasted after surgical operation, thus allowing easy supply of raw materials, but also takes advantage of natural substances, thereby being free from the risk of side effects even upon long-term administration. The composition of the present disclosure promotes the secretion of collagen, reduces reactive oxygen species and promotes re-epithelialization at wound site while remarkably inhibiting melanocyte proliferation, tyrosinase activity and melanogenesis. Accordingly, it can facilitate effective recovery from skin tissue damage caused by oxidative stress, physical wound, intrinsic aging at cell or tissue levels, or hyperpigmentation.

Abstract: The presented invention relates to a CP2c-targeting peptide-based anticancer agent. A CP2c-targeting peptide according to the presented invention binds to transcription factor CP2c to inhibit the formation of transcription factor CP2c complexes (CP2c homotetramer and CP2c/CP2b/PIAS1 heterohexamer), thereby inducing cancer cell-specific cell death. A fatty acid is bound to the peptide to ensure stability enabling long-term sustenance in vivo.

Abstract: Provided is an antibacterial composition against carbapenem-resistant gram-negative bacteria which includes, as an active ingredient, adenylate kinase (ADK) protein derived from Mycobacterium tuberculosis. The ADK protein derived from Mycobacterium tuberculosis, according to the subject matter, has excellent antimicrobial activity against carbapenem-resistant gram-negative bacteria, and thus may be usefully used in a variety of fields as an antibacterial composition.

Abstract: The present invention relates to a composition for preventing or treating sepsis or septic shock including a Mycobacterium tuberculosis-derived adenosine kinase (ADK) protein as an active ingredient. The Mycobacterium tuberculosis-derived ADK protein according to one exemplary embodiment of the present invention has an effect of inhibit binding between the LPS and cells by binding to LPS, and also has an excellent therapeutic effect against sepsis by enhancing viability in a sepsis animal model and suppressing inflammatory response in the lung and cell death in the spleen.

Abstract: The present invention relates to an antibacterial composition containing, as an active ingredient, adenylate kinase or adenosine kinase (ADK) protein derived from Mycobacterium tuberculosis, and a composition for preventing or treating infectious diseases. In addition, the present invention relates to a composition for preventing or treating sepsis or septic shock. Furthermore, the present invention relates to a method for preventing, improving or treating an infectious disease comprising administering the present antibacterial composition. The ADK protein derived from Mycobacterium tuberculosis according to the present invention has excellent antibacterial activity selectively against gram-negative bacteria, and thus can be favorably used as an antibacterial composition against gram-negative bacteria or for the prevention or treatment of infectious diseases caused by gram-negative bacteria.

Abstract: A system and method for generating air plasma by radiating a laser in the air, and making a user feel a somatic sense such as a tactile sense, a thermal sense or the like using a principle of inducing a state change in a medium as a result of a shock wave or an electric field generated by the air plasma.

Abstract: The present invention relates to an antibacterial composition containing, as an active ingredient, adenylate kinase or adenosine kinase (ADK) protein derived from Mycobacterium tuberculosis, and a composition for preventing or treating infectious diseases. In addition, the present invention relates to a composition for preventing or treating sepsis or septic shock. Furthermore, the present invention relates to a method for preventing, improving or treating an infectious disease comprising administering the present antibacterial composition. The ADK protein derived from Mycobacterium tuberculosis according to the present invention has excellent antibacterial activity selectively against gram-negative bacteria, and thus can be favorably used as an antibacterial composition against gram-negative bacteria or for the prevention or treatment of infectious diseases caused by gram-negative bacteria.

Abstract: An endoscope system for diagnosis support and a method for controlling the same. An endoscope module and an endoscope adaptor module are capable of taking images in the body and further measuring the temperature, humidity, volume and air flow in the body. According to the images, temperature, humidity, volume and air flow in the body, an auxiliary diagnosis module may diagnose suspected diseases in the body and may display, to the outside, a disease diagnosis list for the suspected diseases in the body.

Abstract: The present invention relates to a system for fundamentally eliminating skin damage caused by direct radiation of a laser beam on the skin of a user and inducing a somatic sensation on the skin within a safety standard by radiating a pulse laser beam on a medium attached to the skin of the user on which the somatic sensation is desired to be induced. Particularly, the present invention relates to a somatic sensation induction system which can induce a somatic sensation of various feelings delivered to a user by adjusting an absorption coefficient of a medium contacting with the skin of a user, energy intensity and a repetition rate of a radiated laser beam and the like.

Abstract: Provided is an antibacterial composition against carbapenem-resistant gram-negative bacteria which includes, as an active ingredient, adenylate kinase (ADK) protein derived from Mycobacterium tuberculosis. The ADK protein derived from Mycobacterium tuberculosis, according to the subject matter, has excellent antimicrobial activity against carbapenem-resistant gram-negative bacteria, and thus may be usefully used in a variety of fields as an antibacterial composition.