Abstract: The present invention relates to a pharmaceutical composition for preventing or treating macular degeneration containing trametinib or gefitinib, and to a method of screening a therapeutic agent for macular degeneration. The pharmaceutical composition of the present invention is capable of inhibiting the phosphorylation of keratin 8 and the reorganization thereof around nuclei in retinal pigment epithelial cells under oxidative stress conditions, increasing the expression of E-cadherin, and reducing the expression of vimentin, and can thus be efficiently useful for the prevention or treatment of macular degeneration.

Abstract: A barristor-based photodetector is disclosed. The photodetector according to an embodiment comprises: a substrate; a gate electrode which is laminated on the substrate; a first electrode and a second electrode which are laminated on the substrate and spaced apart from the gate electrode; a graphene layer which is formed between the substrate and the second electrode and extends toward the first electrode; and a gate insulating layer which is formed between the gate electrode and the graphene layer.

Abstract: A barristor-based photodetector is disclosed. The photodetector according to an embodiment comprises: a substrate; a gate electrode which is laminated on the substrate; a first electrode and a second electrode which are laminated on the substrate and spaced apart from the gate electrode; a graphene layer which is formed between the substrate and the second electrode and extends toward the first electrode; and a gate insulating layer which is formed between the gate electrode and the graphene layer.

Abstract: Disclosed are a two-dimensional semiconductor in which an energy band gap changes with thickness, a manufacturing method therefor, and a semiconductor device comprising the same. A two-dimensional semiconductor according to an embodiment comprises: a first layer having a first thickness; and a second layer having a second thickness, wherein the first thickness and the second thickness are different from each other, the first layer forms a first junction with a first electrode, and the second layer forms a second junction with a second electrode.

Abstract: The present invention relates to an apparatus and a method of removing water contained in a gaseous material. An apparatus of removing water by phase-changing water contained in a gaseous material to a frost phase includes a gas inflow unit 100, a main body 200, a discharging unit 300, and a frost discharging unit 400. A method of removing water by phase-changing water contained in a gaseous material to a frost phase includes phase-changing water contained in gas to a frost phase, separating the phase-changed frost and the gas from which water is removed, discharging the gas from which the water is removed to the outside, and discharging the phase-changed frost to the outside.

Abstract: A neuron circuit and an operating method thereof are disclosed. The neuron circuit may include an input unit to which an input pulse is applied, a bipolar memristor configured to have one end connected to one end of the input unit, a first capacitor configured to be connected between the one end of the bipolar memristor and a ground, a first diode configured to have an anode connected to the one end of the bipolar component, a second capacitor configured to have one end connected to a cathode of the first diode, a first switch configured to be connected between the one end of the second capacitor and the ground, and a second switch configured to be connected between the anode of the first diode and the other end of the second capacitor.

Abstract: Disclosed are a composition for PCR including polyethylene glycol-engrafted nano-sized graphene oxide (PEG-nGO), the composition for PCR being capable of increasing the efficiency and specificity of PCR and shortening PCR time, and a PCR method using the same.

Abstract: A damping device for structure includes a base frame installed on a target place, an air floating mass disposed on the base frame to blow off air, a TMD mass disposed above the base frame to float with an air pressure, one pair of guiderail units disposed on X-direction both sides of the base frame along the X direction respectively, slider units disposed to be slidable in the X direction relative to the guiderail units, coupled to each X-direction side face of the TMD mass and each including a slider moving up/down mechanism part which moves down a slider when the TMD mass floats, an oil damper attached to the base frame to exert an attenuation action on the TMD mass and a coil spring attached to the base frame to exert a restoration action on the TMD mass.

Abstract: The present invention relates to a preprocessing apparatus and a preprocessing method for measuring and analyzing air pollution, and provides the preprocessing apparatus and the preprocessing method, in which there is included a cyclone main body, a block made of aluminum or copper and provided at an outer circumferential edge of the cyclone main body, and a cooling means surrounding the block, such that contaminated gas introduced into the cyclone main body is cooled within a predetermined range, and as a result, it is possible to remove moisture contained in combustion gas by crystallizing the moisture, and to separate particulate matters from the combustion gas based on a cyclone principle.

Abstract: The present invention relates to an antimicrobial peptide having an improved antibacterial effect through glutamic acid substitution and, more specifically, to a use of the antimicrobial peptide as an active ingredient in an antibacterial pharmaceutical composition, a food additive, a feed additive, an antiseptic composition, and an antibacterial quasi-drug composition. Not only does the antimicrobial peptide of the present invention exhibit significant antibacterial activity against gram-negative bacteria, but it also exhibits a significant synergistic effect when combinedly treated with antibiotics which have strong antibacterial activity only against gram-positive bacteria and has no or low antibacterial activity against gram-negative bacteria, thereby exhibiting excellent antibacterial effects on gram-positive bacteria, E. coli and Acinetobacter bacteria among gram-negative bacteria, and antibiotic-resistant strains thereof.

Abstract: A coil alignment method performed in a coil alignment apparatus coupled to a VA controller includes: sensing magnetic field intensities induced from a ground assembly (GA) coil through a first auxiliary coil and a second auxiliary coil which are fixedly coupled to a VA coil; comparing a first magnetic field intensity sensed through the first auxiliary coil with a second magnetic field intensity sensed through the second auxiliary coil; moving the VA coil or the GA coil to a position where there is a predetermined difference or less between the first magnetic field intensity and the second magnetic field intensity; and moving at least one of the VA coil and the GA coil in a direction facing each other, so that a center point of the VA coil and a center point of the GA coil are located within a shortest distance of each other or within a certain error range of the shortest distance, while maintaining the predetermined difference or less between the first magnetic field intensity and the second magnetic field in

Abstract: Disclosed are a two-dimensional semiconductor in which an energy band gap changes with thickness, a manufacturing method therefor, and a semiconductor device comprising the same. A two-dimensional semiconductor according to an embodiment comprises: a first layer having a first thickness; and a second layer having a second thickness, wherein the first thickness and the second thickness are different from each other, the first layer forms a first junction with a first electrode, and the second layer forms a second junction with a second electrode.

Abstract: The present invention relates to a pharmaceutical composition for preventing or treating macular degeneration containing trametinib or gefitinib, and to a method of screening a therapeutic agent for macular degeneration. The pharmaceutical composition of the present invention is capable of inhibiting the phosphorylation of keratin 8 and the reorganization thereof around nuclei in retinal pigment epithelial cells under oxidative stress conditions, increasing the expression of E-cadherin, and reducing the expression of vimentin, and can thus be efficiently useful for the prevention or treatment of macular degeneration.

Abstract: Disclosed are alignment methods and apparatuses for power transmission/reception coils in an electric vehicle wireless power transfer system. An alignment method may comprise moving a primary coil such that a reference center point of the primary coil sequentially passes through a plurality of measurement points located on the primary coil or located outside the primary coil; measuring physical quantities induced in the primary coil by a power or a magnetic field of a secondary coil magnetically coupled with the primary coil at the reference center point and the plurality of measurement points; and calculating a relative position of the primary coil with respect to the secondary coil based on the measured physical quantities.

Abstract: A nonvolatile protein memory system with optical write/erase and electrical readout capability is provided. The nonvolatile protein memory system includes: a substrate including a microfluidic channel having a pH gradient; a photosensitive protein disposed in the microfluidic channel; and a first electrode and a second electrode disposed on the microfluidic channel and spaced apart from each other and detecting a position change of the photosensitive protein in the microfluidic channel.

Abstract: A coil alignment method performed in a vehicle-side coil alignment apparatus coupled to a vehicle assembly (VA) controller includes: moving a light-blocking unit protruding from a vehicle parked in a wireless charging area in a first direction toward the ground facing one side of a vehicle-side wireless power transfer pad which is mounted on the vehicle and includes a VA coil, where the light-blocking unit protrudes from the one side of the vehicle-side wireless power transfer pad; stopping movement of the light-blocking unit in response to a first stop signal from a ground assembly (GA) controller; moving the light-blocking unit in a second direction perpendicular to the first direction; and stopping movement of the light-blocking unit in response to a second stop signal from the GA controller.

Abstract: Disclosed are a nanopipette provided with a membrane containing a saturated ion-sensitive material, a method for preparing the same, and an ion measuring apparatus comprising the same.

Abstract: The present invention relates to improving the enzymatic activity of Escherichia coli O157:H7-derived sugar isomerase by molecular mechanics and site-directed mutagenesis. More particularly, the present invention relates to a sugar isomerase having an enzymatic activity improved by mutation, a nucleic acid molecule encoding the same, a vector comprising the nucleic acid molecule, a transformant comprising the vector, a mutant of the sugar isomerase, and a method for producing L-gulose using the improved sugar isomerase.

Abstract: Provided are pixel circuits using organic light emitting diodes (OLEDs) and a driving method thereof, and an organic light emitting display including the pixel circuits. The OLED is driven to emit light by a drive transistor generating a drive current compensated with respect to a threshold voltage difference and mobility deviation. The drive transistor may receive reference voltage and data signals in response to separate scan signals supplied to the pixel circuits via different scan lines. As a result, a threshold voltage compensation time, which may include the time during which a reference voltage is supplied to the drive transistor in response to a particular scan signal, may be set long enough regardless of a time during which the data signal is supplied to the pixel circuits located in respective rows of the organic light emitting display in response to a separate scan signal.

Abstract: A textile electrode kit mounted to the clothing includes a contact-type electrode or a non-contact electrode, and the textile electrode kit may be mounted to a clothing having a lower fixed member configured to reduce a motion artifact and a partially three-dimensional clothing structure by means of sewing. On occasions, the textile electrode kit having a non-contact electrode may be inserted into and used in an electrode-mounting pocket or an electrode-mounting tunnel formed at the clothing. The textile electrode kit of the present disclosure may detect various kinds of bio signals such as a heart activity signal, an electrocardiogram (ECG) signal, an electromyogram signal, a breathing signal or the like.