Patents Assigned to KONRAD-ZUSE-INSTITUT
  • Fentanyl derivatives as pH-dependent opioid receptor agonists
    Patent number: 9133120
    Abstract: The invention relates to fluorinated fentanyl derivatives that function as opioid receptor agonists, which activate target opioid receptors in a pH-dependent manner, and are thus selective for the receptors in inflamed (acidic) milieu; uses thereof and pharmaceutical compositions comprising them.
    Type: Grant
    Filed: August 17, 2012
    Date of Patent: September 15, 2015
    Assignees: CHARITÉ—UNIVERSITÄTSMEDIZIN BERLIN, KONRAD-ZUSE-INSTITUT
    Inventors: Christoph Stein, Marcus Weber, Christian Zöllner, Olga Scharkoi
  • FENTANYL DERIVATIVES AS PH-DEPENDENT OPIOID RECEPTOR AGONISTS
    Publication number: 20140228406
    Abstract: The invention relates to fluorinated fentanyl derivatives that function as opioid receptor agonists, which activate target opioid receptors in a pH-dependent manner, and are thus selective for the receptors in inflamed (acidic) milieu; uses thereof and pharmaceutical compositions comprising them.
    Type: Application
    Filed: August 17, 2012
    Publication date: August 14, 2014
    Applicants: KONRAD-ZUSE-INSTITUT, CHARITÉ UNIVERSITÃTSMEDIZIN BERLIN
    Inventors: Christoph Stein, Marcus Weber, Christian Zöllner, Olga Scharkoi