Abstract: Provided is a novel bacterial strain Bacteroides vulgatus MGM001 (Bacteroides vulgatus MGM001) and its use. The LPS from the strain of the subject matter has cytotoxicity weaker than the conventional ones and shows synergistic effect on the inhibition of biofilm formation when used in combination with LTA.
Type:
Grant
Filed:
September 20, 2019
Date of Patent:
January 30, 2024
Assignees:
SOGANG UNIVERSITY RESEARCH & BUSINESS DEVELOPMENT FOUNDATION, KOREA FOOD & DRUG ADMINISTRATION
Inventors:
Kyu-Ho Lee, Hyo-Sun Kwak, Youchul Jung, Kyung Jo Lee, Jeong-A Kim, Boram Jang, Sebin Kang
Abstract: The present invention relates to a method for detecting a target analyte using a gold nanoparticle, comprising growing a copper crystal specifically on a gold nanoparticle by treating the gold nanoparticle with a solution comprising a copper ion, a polymer having a primary or secondary amine group, and a reducing agent, a composition for amplifying a signal used in the detection method above, and a kit for detecting a target analyte comprising the composition for amplifying a signal above.
Type:
Grant
Filed:
February 14, 2018
Date of Patent:
September 5, 2023
Assignees:
KOREA FOOD & DRUG ADMINISTRATION, SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION
Inventors:
Jwa-Min Nam, Gwangpyo Ko, Jae-Ho Kim, Jeong-Eun Park, Mouhong Lin, In Sun Joo, Jeong Su Lee
Abstract: The present disclosure relates to methods of predicting treatment sensitivity or drug resistance, especially for epidermal growth factor receptor (EGFR) inhibitors using leucine proline-enriched proteoglycan 1 (LEPRE1) gene expression level before or during a treatment, methods of discovering companion diagnostic biomarkers using efficacies of EGFR inhibitors on the expression of genes, including genes involved with regulation of extracellular matrix environment, or metabolism of collagen, and methods of predicting treatment sensitivity or resistance of drugs using the companion diagnostic biomarkers thereof.
Type:
Application
Filed:
December 19, 2022
Publication date:
April 27, 2023
Applicants:
SYNTEKABIO, INC., KOREA FOOD & DRUG ADMINISTRATION
Abstract: Provided is a novel bacterial strain Bacteroides vulgatus MGM001 (Bacteroides vulgatus MGM001) and its use. The LPS from the strain of the subject matter has cytotoxicity weaker than the conventional ones and shows synergistic effect on the inhibition of biofilm formation when used in combination with LTA.
Type:
Application
Filed:
September 20, 2019
Publication date:
May 28, 2020
Applicants:
SOGANG UNIVERSITY RESEARCH & BUSINESS DEVELOPMENT FOUNDATION, KOREA FOOD & DRUG ADMINISTRATION
Inventors:
Kyu-Ho LEE, Hyo-Sun KWAK, Youchul JUNG, Kyung Jo LEE, Jeong-A KIM, Boram JANG, Sebin KANG
Abstract: Disclosed are a DNA aptamer specifically binding to the Her2 (ERBB2) receptor involved in the onset of breast cancer, a composition for the suppression of cancer metastasis comprising the same as an active ingredient, and a composition for the diagnosis of cancer comprising the same as an active ingredient. Due to its binding mechanism being different from that of the conventional antibody, the aptamer can be effectively used for suppressing cancer metastasis and diagnosing cancer.
Type:
Grant
Filed:
August 10, 2011
Date of Patent:
April 12, 2016
Assignees:
POSTECH ACADEMY-INDUSTRY FOUNDATION, KOREA FOOD & DRUG ADMINISTRATION
Inventors:
Jung Hwan Lee, Young Chan Chae, Youngdong Kim, Hyungu Kang, Jong Hun Im, Jong In Kim, Ki Seok Kim, Sung Key Jang, Il Ung Oh, Min Jeong Choi, Won Jun Kang
Abstract: Disclosed are a DNA aptamer specifically binding to the Her2 (ERBB2) receptor involved in the onset of breast cancer, a composition for the suppression of cancer metastasis comprising the same as an active ingredient, and a composition for the diagnosis of cancer comprising the same as an active ingredient. Due to its binding mechanism being different from that of the conventional antibody, the aptamer can be effectively used for suppressing cancer metastasis and diagnosing cancer.
Type:
Application
Filed:
August 10, 2011
Publication date:
January 1, 2015
Applicants:
KOREA FOOD & DRUG ADMINISTRATION, POSTECH ACADEMY-INDUSTRY FOUNDATION
Inventors:
Jung Hwan Lee, Young Chan Chae, Youndong Kim, Hyungu Kang, Jong Hun Im, Jong In Kim, Ki Seok Kim, Sung Key Jang, II Ung Oh, Min Jeong Choi, Won Jun Kang
Abstract: Disclosed are a method and a system for estimating food commodity intakes.
Type:
Application
Filed:
June 27, 2011
Publication date:
July 25, 2013
Applicants:
Korea Food & Drug Administration, Sejong University Industry Academy Cooperation Foundation, The Korea Health Industry Development Institute
Inventors:
Sang Hoon Ko, Seung Won Kim, Ki Sung Kwon, Jae Ho Oh, Jung Ah Do, Joong Keun Lee, Hee Dong Woo
Abstract: Disclosed herein is a system for managing chemicals using Radio-Frequency Identification (RFID). A storage facility identification tag, attached to a chemical storage facility in a laboratory, stores the unique identification code of the chemical storage facility and a list of chemicals. A chemical identification tag, attached to the cover of a chemical container, stores the unique identification code of the chemical storage facility and chemical-related information. A mobile terminal, provided with an RFID reader, receives and outputs the unique identification code of the chemical storage facility, the list of the chemicals, and the chemical-related information.
Type:
Application
Filed:
October 30, 2008
Publication date:
October 1, 2009
Applicant:
REPUBLIC OF KOREA (KOREA FOOD & DRUG ADMINISTRATION)
Inventors:
Sang Mok Lee, Kun Sang Park, Woo Sung Kim, Ho Il Kang, Chang Hee Lee, Dong Kil Lim, Yong Suk Ko, So Hee Kim, Dae Hyun Jo, Dai Byung Kim, Won Gon Yoo
Abstract: Disclosed herein is a method of preparing trans fat-free oils and fats by an enzymatic interesterification (EI), and trans fat-free oils and fats prepared by the method. Specifically, the method comprises the steps of: 1) mixing fully hydrogenated fat derived from vegetable oil with RBD olive oil; 2) adding lipase to the mixed oil and reacting the mixed oil with lipase at 65 to 80° C. for 1 to 4 hours (1st reaction step); and 3) reacting the mixed oil from step 2) with the lipase at 40 to 60° C. for 44 to 47 hours (2nd reaction step).
Type:
Application
Filed:
December 11, 2008
Publication date:
June 18, 2009
Applicant:
Republic of Korea (Management: Korea Food & Drug Administration)
Inventors:
In Hwan KIM, Sun Mi Lee, Bo Mi Lee, Ji Eun Oh, Myung Chul Kim, Hye Kyung Park, Jong Wook Kim, Kwang II Kwon, Jee Young Kim, Jee Sun Lee