Patents Assigned to KOREA INSTITUTE OF SCIENCE AN TECHNOLOGY
  • Patent number: 11992939
    Abstract: The present disclosure provides a robot palm, which includes: a housing having a particle-containing space configured to accommodate particles so that a pressure thereof is changeable; particles filled in the particle-containing space; and an upper membrane installed at an upper portion of the housing and configured to grip an object by changing its shape and rigidity according to a pressure change of the particle-containing space.
    Type: Grant
    Filed: July 29, 2021
    Date of Patent: May 28, 2024
    Assignee: Korea Institute of Science and Technology
    Inventors: Sungwook Yang, Jeongwon Lee, Jaehee Kim, Donghyun Hwang, Yong Seok Ihn
  • Patent number: 11988651
    Abstract: The present invention relates to a metabolome sampling and analysis method for analyzing metabolome during synthetic gas fermentation of a synthetic gas fermentation microorganisms, the method establishing an optimal condition for metabolome sampling and enabling a glucose culture and a synthetic gas culture of the synthetic gas fermentation microorganisms to be distinguished by using a selected metabolomic biomarker.
    Type: Grant
    Filed: February 21, 2019
    Date of Patent: May 21, 2024
    Assignees: Korea University Research and Business Foundation, Korea Institute of Science and Technology
    Inventors: Kyoung Heon Kim, Young Soon Um, Jung Yeon Kim, Joongsuk Kim
  • Publication number: 20240159744
    Abstract: The present disclosure relates to a cancer cell-specific complex for targeting cancer. The complex for targeting cancer according to the present disclosure includes EGF, but is affected more by lysosomal activity rather than the EGFR signaling pathway, and thus can overcome the shortcomings of the existing EGF therapy-based diagnostic and therapeutic compositions and provide successfully personalized and improved effects of treating, preventing and alleviating cancer. A diagnostic composition according to the present disclosure enables the prediction of the anticancer performance of a therapeutic composition of the present disclosure in a subject, and thus enables anticancer treatment to be designed stably.
    Type: Application
    Filed: August 12, 2021
    Publication date: May 16, 2024
    Applicants: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY, KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION
    Inventors: Ju Hee RYU, Ick Chan KWON, Kwangmeyung KIM, Han Young KIM, Eun-sun KIM
  • Publication number: 20240158851
    Abstract: Disclosed is a composition for diagnosing, preventing or treating drug addiction based on synaptotagmin binding cytoplasmic RNA interacting protein (SYNCRIP). SYNCRIP or a gene encoding the protein can be used to diagnose drug addiction. In addition, a therapeutic agent for drug addiction can be discovered by measuring the expression of SYNCRIP. Furthermore, an agent expressing SYNCRIP or promoting the activity of SYNCRIP can be used to prevent or treat drug addiction.
    Type: Application
    Filed: January 23, 2024
    Publication date: May 16, 2024
    Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Heh-In IM, Baek Sun KIM, Sung Hyun TAG
  • Patent number: 11982619
    Abstract: A method for detecting biomaterial by means of a dye having a linear upconversion fluorescent property is provided. The method includes the steps of: i) preparing a fluorophore having a linear upconversion fluorescent property; ii) reacting the fluorophore and biomaterial to obtain a reaction complex thereof; iii) exciting the reaction complex by means of a light source having a longer wavelength than the maximum light-emitting wavelength of the fluorophore; and iv) detecting and measuring the light-emitting signal having a shorter wavelength than the wavelength of the excited light emitted from the excited reaction complex. A system and a kit for detecting biomaterial using a dye having a linear upconversion fluorescent property are also provided.
    Type: Grant
    Filed: July 22, 2020
    Date of Patent: May 14, 2024
    Assignees: BIONANO HEALTH GUARD RESEARCH CENTER, KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Sehoon Kim, Bong Hyun Chung, Youngsun Kim, Kyung Mi Park, Young Hun Seo
  • Patent number: 11984146
    Abstract: A neuromorphic device including: a plurality of unit weighting elements connected to a bit line in a manner that shares the bit line, each of the plurality of unit weighting elements being connected to a source line and comprising a fixed layer of which a magnetization direction is fixed, a free layer of which a magnetization direction changes in parallel with or in anti-parallel with the fixed layer, and a tunnel barrier layer arranged between the fixed layer and the free layer and a plurality of drive transistors being selectively turned on according to a plurality of bit selection signals, respectively, and correspondingly driving the unit weighting elements, respectively, wherein the plurality of unit weighting elements have different resistances in such a manner as to correspond to bits, respectively, of a synapse weight.
    Type: Grant
    Filed: April 15, 2022
    Date of Patent: May 14, 2024
    Assignee: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventor: Seung Heon Baek
  • Publication number: 20240151728
    Abstract: The disclosure relates to a fluorescence resonance energy transfer (FRET)-based biosensor for sensing chimeric antigen receptor (CAR) activity and use thereof, and in particular, to a FRET-based biosensor, which simultaneously detects binding of an antigen-binding receptor domain to a cancer antigen and consequent activation of T cells, and a method of screening for CAR activity in a live cell by using the FRET-based biosensor.
    Type: Application
    Filed: October 16, 2023
    Publication date: May 9, 2024
    Applicants: Korea Institute of Science and Technology, SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION
    Inventors: Jihye SEONG, Mihue Jang, Haenim Lee, Hyejin Yoo, Chang-Han Lee, Jiyun Jeong, Hang-Rae Kim, Soojin Lee
  • Patent number: 11976314
    Abstract: The present invention relates to a transformed strain having ethanol production potential, constructed by introducing a foreign gene for ethanol production into a non-ethanol producing acetogen Eubacterium limosum and a method for producing ethanol, using the strain. According to the present invention, Eubacterium limosum which is a conventional acetogen lacking ethanol production potential is used to produce ethanol, which is a high value-added product, as a single product from carbon monoxide contained in waste gas.
    Type: Grant
    Filed: August 28, 2018
    Date of Patent: May 7, 2024
    Assignees: GWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY, KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION
    Inventors: In Seop Chang, Jiyeong Jeong, Shinyoung Park, In-Geol Choi, Byeonghyeok Park
  • Patent number: 11969728
    Abstract: The present disclosure relates to a microfluidic device capable of mimicking a biological microenvironment thereby achieving control of a microenvironment with time through control of the diffusion of target elements between chambers by interrupting or generating fluid flow inside a channel, and a method for manufacturing the same, and the microfluidic device according to an aspect of the present disclosure can mimic the biological microenvironment which changes constantly with time via a simple temporary operation of generating or interrupting fluid flow in the channel mechanically and can control diffusion via a simple method, and accordingly, a complicated microenvironment can be reproduced since the number and arrangement of diffusion chambers and channels can be designed variously.
    Type: Grant
    Filed: November 2, 2020
    Date of Patent: April 30, 2024
    Assignee: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Seung Beum Suh, Sunghyun Cho
  • Patent number: 11970394
    Abstract: Provided is a method of synthesizing apatite powder by emitting a laser beam to a surface of a substrate immersed in a precursor solution. The method is including immersing a substrate in an apatite-forming precursor solution, emitting a laser beam to a region on a surface of the substrate immersed in the precursor solution, and obtaining apatite powder generated in the precursor solution.
    Type: Grant
    Filed: December 22, 2020
    Date of Patent: April 30, 2024
    Assignee: Korea Institute of Science and Technology
    Inventors: Hojeong Jeon, Seung Hoon Um, Yu Chan Kim, Hyung-Seop Han, Myoung-Ryul Ok, Hyunseon Seo, Hyun Kwang Seok
  • Patent number: 11968778
    Abstract: Disclosed is a method of manufacturing a stretchable substrate having improved stretch uniformity according to various embodiments of the present disclosure in order to implement the above-described object. The method may include forming an auxetic including a plurality of unit structures, and attaching one or more elastic sheets to the auxetic and forming a stretchable substrate.
    Type: Grant
    Filed: March 24, 2022
    Date of Patent: April 23, 2024
    Assignee: Korea Institute of Science and Technology
    Inventors: Phillip Lee, SeungJun Chung, HeeSuk Kim, JeongGon Son, SukJoon Hwang
  • Patent number: 11967822
    Abstract: Embodiments relate to a method for predicting power generation and remaining useful life to predict operational soundness of a power plant and a system for performing the same, the method including acquiring sensing data from each of a plurality of sensors included in a plurality of systems in the power plant, outputting each of a predicted power generation and a predicted remaining useful life from a measurement value in sensing data of an input sensor through a pre-trained prediction model, assessing the operational soundness in aspect of the power generation and the remaining useful life using a prediction result and a current result in each aspect, and determining the operational soundness of the system based on prediction uncertainty and an assessment result in aspect of the power generation and the remaining useful life.
    Type: Grant
    Filed: September 30, 2021
    Date of Patent: April 23, 2024
    Assignee: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Ig Jae Kim, Heeseung Choi, Yeji Choi, Jisoo Kim
  • Publication number: 20240124943
    Abstract: The present specification may provide a novel single-stranded nucleic acid aptamer capable of simultaneous detection of seven Cronobacter species, a composition or kit for multiple detection comprising the aptamer. The novel single-stranded nucleic acid aptamer of the disclosure can bind to all seven reclassified Cronobacter species, which are pathogenic bacteria, with high binding affinity due to its affinity and specificity. Therefore, the seven Cronobacter species can be easily and efficiently multi-detected from the environment where various bacteria are colonized and inhabited, and from contaminated food and water.
    Type: Application
    Filed: May 26, 2023
    Publication date: April 18, 2024
    Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Byoung Chan KIM, Hye Ri KIM
  • Patent number: 11959193
    Abstract: Disclosed are a spinning dope for an aramid and carbon-nanotube composite fiber and a method of manufacturing an aramid and carbon-nanotube composite fiber using the same.
    Type: Grant
    Filed: March 22, 2022
    Date of Patent: April 16, 2024
    Assignee: Korea Institute of Science and Technology
    Inventors: Dae Yoon Kim, Ki Hyun Ryu, Bon Cheol Ku, Jun Yeon Hwang, Nam Dong Kim, Dong Ju Lee, Seo Gyun Kim
  • Patent number: 11957514
    Abstract: The present disclosure relates to a method for determining a relative position between arrays of a flexible array device. The flexible array device according to an embodiment includes a plurality of arrays arranged at a predetermined interval in a deformable substrate, and the method includes measuring the first capacitance between adjacent arrays, measuring the second capacitance between the adjacent arrays after deformation of the substrate, and determining a relative position between the adjacent arrays based on the first capacitance measurement value and the second capacitance measurement value. According to an embodiment, the relative position between the arrays may be determined by measuring the capacitance between the adjacent arrays of the plurality of arrays arranged in the deformable substrate and measuring a change in capacitance caused by the deformation (contraction, relaxation, bending) of the substrate.
    Type: Grant
    Filed: February 1, 2021
    Date of Patent: April 16, 2024
    Assignee: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Byung Chul Lee, Dong-Hyun Kang, Shinyong Shim
  • Publication number: 20240117247
    Abstract: An upconversion multicolor light-emitting polymer composite implements red, green, and blue colors at wavelengths in each specific region by mixing: an upconversion nanophosphor emitting light in red and blue colors at wavelengths in each specific region by absorbing the infrared light; an upconversion nanophosphor emitting light in green and blue colors at wavelengths in each specific region by absorbing the infrared light; and a polydimethylsiloxane (PDMS) polymer. Accordingly, a volumetric display with excellent color reproducibility may be realized with a simple manufacturing process.
    Type: Application
    Filed: September 19, 2023
    Publication date: April 11, 2024
    Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Ho Seong JANG, Jihoon KYHM, Ja Yeon LEE
  • Publication number: 20240116005
    Abstract: The present invention relates to a method for preparing a 3D biological bilayer membrane structure in a physiological buffer solution and a 3D biological bilayer membrane structure using the same, and more particularly, to a method for preparing a 3D biological bilayer membrane structure that is tightly sealed even under physiological ionic conditions by applying pressure during electroformation to improve a membrane fusion function, and a 3D biological bilayer membrane structure using the same.
    Type: Application
    Filed: September 29, 2023
    Publication date: April 11, 2024
    Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Tae Song KIM, Dong Hyun KANG, Bong Kyu KIM
  • Publication number: 20240115515
    Abstract: The present invention relates to a liver-specific drug delivery carrier comprising a nucleic acid nanoparticle and cholesterol; a liver-specific complex; a pharmaceutical composition for prevention or treatment of liver disease using the same; and a method for preventing or treating liver disease.
    Type: Application
    Filed: February 9, 2023
    Publication date: April 11, 2024
    Applicant: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Dae-Ro AHN, Kyoung-Ran KIM, Junghyun KIM, Ji Eun LEE, Ji hyun BACK
  • Patent number: 11954942
    Abstract: Embodiments relate to a human behavior recognition system using hierarchical class learning considering safety, the human behavior recognition system including a behavior class definer configured to form a plurality of behavior classes by sub-setting a plurality of images each including a subject according to pre-designated behaviors and assign a behavior label to the plurality of images, a safety class definer configured to calculate a safety index for the plurality of images, form a plurality of safety classes by sub-setting the plurality of images based on the safety index, and additionally assign a safety label to the plurality of images, and a trainer configured to train a human recognition model by using the plurality of images defined as hierarchical classes by assigning the behavior label and the safety label as training images.
    Type: Grant
    Filed: December 30, 2021
    Date of Patent: April 9, 2024
    Assignee: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Junghyun Cho, Ig Jae Kim, Hochul Hwang
  • Patent number: 11944958
    Abstract: Disclosed herein are a catalyst for hydrocracking reaction of high molecular weight components in bio-oil, a method for preparing the same and a method for bio-oil upgrading using the same. The catalyst includes a zeolite carrier; and at least one metal selected from the group consisting of nickel (Ni), ruthenium (Ru) and cerium (Ce) supported on the carrier. The catalyst promotes the hydrocracking of high molecular weight compounds contained in the bio-oil, but also inhibits the polymerization reaction of the decomposed product, thereby more effectively enhancing the hydrocracking reaction of the bio-oil.
    Type: Grant
    Filed: July 18, 2022
    Date of Patent: April 2, 2024
    Assignee: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Chunjae Yoo, Jeong-Myeong Ha, Dong Jin Suh, Jae Wook Choi, Young Hyun Yoon, Kyeongsu Kim, Chang Soo Kim, Kwang Ho Kim, Thi Lien Do