Abstract: A method of detecting vitamin D in blood using laser desorption/ionization mass spectrometry (LDI-MS) and an apparatus therefor according to the present invention are not complicated in a measurement, do not require a number of measurement steps, and allow for easy measurement and collection of results in real time with a quick analysis. In addition, precise analysis may be performed even at a lower concentration of a sample, such that sensitivity and precision are excellent, various subtypes of vitamin D may be simultaneously detected, a throughput is high, and structural analysis and quantitative analysis of vitamin D that has undergone a metabolic process in blood may be accurately performed without a matrix interference.

Abstract: An embodiment of the present disclosure provides a multi-reflection silicon-based liquid immersion micro-channel measurement device and measurement method capable of improving measurement sensitivity by completely separating, through multi-reflection, first reflective light reflected by a sample detection layer and a second reflective light by a prism-buffer solution interface and by allowing the light to enter multiple times through the multi-reflection.

Abstract: The present disclosure relates to a surface-enhanced Raman spectroscopy complex probe capable of effectively detecting a catecholamine compound even at extremely low concentrations. The complex probe includes a nanolaminate including a nanogap and metal nanoparticles. In this case, the nanolaminate and the metal nanoparticles are modified to a compound that may be bound to each functional group included in catecholamine, and thus, catecholamine included in an analyte is doubly recognized by the complex probe. In addition, since a hotspot emitting a strong SERS signal is formed by a nanogap included in a nanolaminate, it is possible to effectively detect a catecholamine compound even at extremely low concentrations.

Abstract: A gradient-index phononic crystal flat lens which controls the behavior of an acoustic wave having a designated frequency. The gradient-index phononic crystal flat lens may include one or more super cells each having a plurality of layers stacked in a vertical direction according to a target gradient index profile, wherein each of the layers is composed of an aggregate in which unit cells having scatterers formed with the same size in the centers thereof are arranged in a horizontal direction. The one or more super cells may each include a divider provided between the neighboring layers, and configured to force the acoustic wave to propagate in the horizontal direction within the gradient-index phononic crystal flat lens.

Abstract: Disclosed is a method and apparatus for measuring magnetic field and/or temperature using a diamond nitrogen-vacancy center sensor, and a measuring apparatus based on a diamond nitrogen-vacancy center (DNV) sensor may include: a diamond nitrogen-vacancy center sensor; a frequency synthesizer for generating a first reference signal and a second reference signal; a first microwave generator for generating a first microwave that is frequency modulated according to the first reference signal and causes a first spin transition in the diamond nitrogen-vacancy center sensor; a second microwave generator for generating a second microwave that is frequency modulated according to the second reference signal and causes a second spin transition in the diamond nitrogen-vacancy center sensor; a laser irradiator for applying a laser to excite the spin state of the diamond nitrogen-vacancy center sensor; a power amplifier for combining and amplifying the first microwave and the second microwave to apply to the diamond nitrog

Abstract: A magnetic resonance imaging (MRI) vibration measurement device for measuring vibrations of an object inserted into an MRI scanner, includes: a human phantom holding apparatus including a human phantom inserted into the MRI scanner in a direction (z-axis, head-to-foot direction); a light source which emits light; a mirror structure which emits the light to the human phantom and provides light reflected by the human phantom; an optical sensor which measures the reflected light to detect z-axis direction vibrations of the human phantom; and a vibration sensor part which is disposed in the human phantom holding apparatus and detects vibrations in both x-axis and y-axis directions which are perpendicular to each other and orthogonal to the z-axis.

Abstract: The present invention relates to particle measuring apparatus and a particle measuring method, whereby particle counts per size range can be measured with a high accuracy using a laser power scanning in which lasers of several powers are sequentially irradiated. First, minimum powered lasers capable of measuring particles having more than relevant size are irradiated to a particle measurement space for a predetermined time in response to plural counts of each mutually different particle size, and the counts of particles per size are measured by detecting a scattered light. Furthermore, the counts of particles belonging to each size range can be accurately calculated through an algorithm using the actually measured value.

Abstract: The present disclosure relates to a thermocouple wafer calibration system including: a main body portion composed of a chamber forming a sealed space, and a support installed a lower edge of the chamber and supporting the chamber to be spaced apart from the ground; a thermocouple wafer composed of a plate installed to be horizontal inside the sealed space of the chamber, and a first thermocouple unit attached to a upper surface of the plate so as to form a plurality of first measurement contact points; a calibration portion provided with a second thermocouple unit penetrating the chamber in a space where the chamber spaced from the ground, then partially accommodated inside the sealed space, and calibrated to form a plurality of second measurement contact points in contact with a lower surface of the plate at a position corresponding to each of the first measurement contact points; a temperature measurement portion partially accommodated inside the sealed space of the chamber and measuring a temperature of th

Abstract: A method for detecting organic matter in the blood by using LDI-MS, and a device therefor, according to the present invention, are not complicated when performing measurement and do not require the passage of many steps, and facilitate, in real time, measurement and result collection through rapid analysis. In addition, the present invention enables precise analysis even at a lower sample concentration so as to have excellent sensitivity and accuracy, enables the detection of various types of organic matter at the same time and has high throughput, and enables the structure analysis of organic matter, having undergone metabolic processes in the blood, and quantitative analysis thereof to be accurately performed without interference from a matrix.

Abstract: A strain measuring device includes a first sensing optical fiber disposed on a surface of a measurement target. A second sensing optical fiber is spaced apart from the first sensing optical fiber and arranged parallel to the first sensing optical fiber. The second sensing optical fiber is spaced apart from the surface of the measurement target. An optical fiber guide has an inner cavity. The optical fiber guide is bonded to the surface of the measurement target to be positioned on the surface of the measurement target. The second sensing optical fiber is disposed in the inner cavity. A controller receives measured values from the first sensing optical fiber and the second sensing optical fiber. The first sensing optical fiber and the second sensing optical fiber include optical fibers for measuring strain.

Abstract: Provided is a method of preparing Raman-active nanoparticles, which includes a) preparing a metal nanocore having a nano-star shape from a first reaction solution in which a first metal precursor is mixed with a buffer solution; b) fixing a Raman reporter in the metal nanocore; and c) forming a metal shell, which surrounds the nanocore in which the Raman reporter is fixed, from a second reaction solution in which a second metal precursor is mixed with the nanocore in which the Raman reporter is fixed. The Raman reporter has a binding affinity for each of a first metal of the metal nanocore and a second metal of the metal shell.

Abstract: The present invention relates to an eye phantom for evaluating a retinal angiography image, and a manufacturing method therefor. A purpose of the present invention is to provide an eye phantom for evaluating a retinal angiography image, capable of simulating even the vascular structure and blood flow of a retina so as to be more similar to an actual retinal structure than a conventional eye phantom; and a manufacturing method therefor. More specifically, a purpose of the present invention is to provide an eye phantom for evaluating a retinal angiography image, including various shapes of fine fluid channel structures corresponding to the vascular structure formed in an actual retina; and a manufacturing method therefor.

Abstract: Provided is a method of monitoring a heart rate of an open circulatory system aquatic organism including water fleas, zebrafish, brine shrimp, and the method of evaluating individual response by real time measurement of a heart rate of an aquatic organism and the individual response evaluation apparatus by real time measurement of a heart rate of an aquatic organism according to the present invention may effectively fix the aquatic organism for real time measurement of the heart rate of an aquatic organism, and may measure the heart rate using digital holography to display the heart rate while configuring a data format to allow the corresponding data to be stored for a long time, thereby treating a compound for inducing an individual response, securing a heart rate change in real time by image processing, and then effectively determining the presence or absence of harmfulness due to induction of the individual response.

Abstract: A large-area wrinkled graphene substrate capable of being manufactured in a large-area, and a method for manufacturing the same is provided. A method for manufacturing a wrinkled graphene substrate includes: i) providing a graphene unit; ii) inserting a carrier film and a graphene unit between a pair of rolls and rotating the pair of rolls in opposite directions to attach a carrier film on the graphene unit, iii) immersing the graphene unit in an etching solution to provide graphene, iv) between a pair of rolls, graphene and poly(4-styrene sulfonic acid)/polystyrene (PSS/PS) substrate attaching graphene onto the PSS/PS substrate, v) attaching an ethylene vinyl acetate/polyethylene terephthalate (EVA/PET) substrate to wrinkled graphene on PSS/PS substrate by inserting EVA/PET and WGr/PSS/PS stack between the rolls, viii) removing the PSS/PS substrate by immersing PET/EVA/WGr/PSS/PS stack in water, and ix) providing a wrinkled graphene substrate on the EVA/PET substrate.

Abstract: The present disclosure relates to an apparatus and method for measuring the thickness and refractive index of a multilayer thin film by measuring angle-resolved spectral reflectance according to light polarization. According to an exemplary embodiment of the present disclosure, the apparatus and method for measuring the thickness and refractive index of a multilayer structure using angle-resolved spectroscopic reflectometry is capable of measuring and analyzing thickness and refractive index of each layer of a structure having a multilayer thin film through an s-polarized imaging and a p-polarized imaging of the reflective light located in a back focal plane of an objective lens which are acquired through an angle-resolved spectral imaging acquisition part.

Abstract: A method of measuring a specific absorption rate (SAR) of a hip joint implant using magnetic resonance imaging (MRI), includes: arranging the hip joint implant in a human lower body-shaped phantom; arranging an electric field sensor around the hip joint implant; providing radio frequency (RF) energy according to an MRI sequence to the human phantom; and calculating the SAR of the hip joint implant from strength of an electric field measured by the electric field sensor.

Abstract: The present invention relates to a planar-type plasma diagnosis apparatus comprising: a transmission antenna for applying a frequency-variable microwave to plasma; a reception antenna for receiving the microwave from the plasma; and a body part encompassing the transmission antenna and the reception antenna so that same are insulated from each other, wherein the upper surface of the transmission antenna for applying the microwave and the upper surface of the reception antenna for receiving the microwave are planar, and side surfaces of the upper surfaces of the transmission antenna and the reception antenna face each other.

Abstract: A battery cell measurement module includes a lower housing having a connection part and a fixing part connected to the lower housing. An upper portion of the fixing part has a battery cell accommodation space accommodating a battery cell. The fixing part includes a connection hole that is in communication with the battery cell accommodation space and has the connection part arranged therein. Module includes a height control part that extends from the battery cell accommodation space to the connection part via the connection hole. Module includes an upper housing detachably attached to the lower housing, arranged to surround the fixing part and the height control part, and provided with a transparent window. The battery cell has an opening in an upper surface of the battery cell and is accommodated in the battery cell accommodation space such that the opening is located at a position vertically overlapping the transparent window.

Abstract: The present disclosure relates to a device and method for forming skyrmion in a magnetic thin film. A skyrmion forming method comprises aligning the surface of the magnetic thin film and a horizontal magnetic field to be applied to the magnetic thin film and applying the horizontal magnetic field and a vertical magnetic field to the magnetic thin film. Accordingly, it is possible to form the bubble skyrmion easily even in the case of a wide width of a stripe formed on the magnetic thin film.

Abstract: The present invention relates to a culture vessel for three-dimensional cell cultivation and a three-dimensional cell co-cultivation method using the same. The culture vessel comprises a well formed by a column positioned thereon and at least one support protruding from the column within the well. In contrast to conventional techniques, the present invention allows cells to be cultured at a position spaced from a culture vessel, thus enjoying the advantage of smoothly supplying oxygen necessary for three-dimensional cell culture structures.