Abstract: Provided is a non-destructive inspection device for pressure containers using leakage-flux measurement, including: a coil winding mount disposed at one side on an outside of the pressure container to magnetize the pressure container; a sensor support provided with a plurality of magnetic field sensing sensors arranged at the other side on the outside of the pressure container; a yoke magnetizing the pressure container to generate a magnetic flux in a direction vertical to a direction of the magnetic flux generated by the coil winding mount; an endoscope attached with at least one magnetic field sensing sensor, and the like.
Type:
Grant
Filed:
January 5, 2012
Date of Patent:
April 12, 2016
Assignee:
KOREA RESEARCH INSTITUTE OF STANDARDS AND SCIENCE
Inventors:
Kwon Sang Ryu, Soo Young Park, Yun-Hee Lee, Seung Hoon Nahm, Un Bong Baek
Abstract: Disclosed are a method and a kit for the quantification of nucleic acids, especially a trace amount of nucleic acid, such as host cell nucleic acid impurities, using real-time PCR with a random primer.
Type:
Grant
Filed:
November 9, 2011
Date of Patent:
March 29, 2016
Assignee:
KOREA RESEARCH INSTITUTE OF STANDARDS AND SCIENCE
Inventors:
In Chul Yang, Min Jung Kang, Han Nah Yu, Sang Ryoul Park, Sook Kyoung Kim
Abstract: A camera tracing and surveillance system and method for security using a thermal image coordinate, whereby an image having high resolution for identification in which a person can be accurately identified within a surveillance area and identity of the person can be accurately checked, can be obtained using a simple algorithm. To this end, the person within the surveillance area is identified and a position coordinate of the person is extracted from a thermal image captured by a thermal image camera, and a tracing and surveillance camera traces the person, enlarges an image of the person, and captures the enlarged image based on the extracted position coordinate so that an image having high resolution for identification can be obtained.
Type:
Grant
Filed:
August 12, 2011
Date of Patent:
March 1, 2016
Assignee:
Korea Research Institute of Standards and Science
Inventors:
Su Un Kim, Man Yong Choi, Jeong Hak Park, Bong Young Ahn
Abstract: Provided is a pharmaceutical composition containing inorganic nanoparticles selected from titanium oxide nanoparticles or silica nanoparticles as an active ingredient for preventing or treating angiogenesis-related diseases. The pharmaceutical composition for preventing or treating angiogenesis-related diseases according to the present invention may be used as a therapeutic agent for various diseases based on angiogenesis such as age-related macular degeneration, tumors, and diabetes-related complications.
Type:
Grant
Filed:
September 20, 2012
Date of Patent:
January 19, 2016
Assignee:
KOREA RESEARCH INSTITUTE OF STANDARDS AND SCIENCE
Inventors:
Tae Geol Lee, Jeong Hun Kim, Dong Hyun Jo
Abstract: An apparatus for forming fine patterns by employing polarization interference in a laser scanning method comprises a laser generator; a calcite wave plate configured to refract at least one of the S wave and the P wave, polarized by the polarization plate, an analyzer configured to make coincident with each other the polarization directions of the S wave and the P wave having the paths spaced apart from each other by the calcite wave plate; an exposure lens; an exposure head; an X stage; and a rotation stage configured to move the substrate mounting unit around a Z axis which is a vertical axis.
Type:
Grant
Filed:
November 12, 2010
Date of Patent:
December 29, 2015
Assignee:
KOREA RESEARCH INSTITUTE OF STANDARDS AND SCIENCE
Abstract: Disclosed herein are a monochromator and a charged particle beam apparatus including the same. The monochromator may include a first electrostatic lens configured to have a charged particle beam discharged by an emitter incident on the first electrostatic lens, refract a ray of the charged particle beam, and include a plurality of electrodes and a second electrostatic lens spaced apart from the first electrostatic lens at a specific interval and configured to have a central axis disposed identically with a central axis of the first electrostatic lens, have the charged particle beam output by the first electrostatic lens incident on the second electrostatic lens, refract the ray of the charged particle beam, and comprise a plurality of electrodes. Accordingly, there is an advantage in that a charged particle beam can have an excellent profile even after passing through the monochromator.
Type:
Application
Filed:
April 27, 2015
Publication date:
December 24, 2015
Applicant:
KOREA RESEARCH INSTITUTE OF STANDARDS AND SCIENCE
Inventors:
Takashi OGAWA, Bok Lae CHO, Sang Jung AHN, In Yong PARK, Cheolsu HAN
Abstract: Provided is a combustion pretreatment-isotope dilution mass spectrometry measuring concentration of a target element for detection contained in a target sample for detection by using an isotope dilution mass spectrometry, including: pretreating the target sample for detection by combustion during an isotope dilution mass spectrometry, to thereby stabilize an isotope and further improve analysis ability, and therefore, the present invention is expected to be utilized as an element analysis method surpassing accuracy of the existing mass spectrometry method.
Type:
Application
Filed:
December 26, 2013
Publication date:
December 3, 2015
Applicant:
KOREA RESEARCH INSTITUTE OF STANDARDS AND SCIENCE
Inventors:
Kyoung-Seok Lee, In Jung Kim, Sung-pil Jo, Hyung Sik Min, Yong Hyeon Yim, Joung Hae Lee, Eui Jin Hwang
Abstract: The present invention relates to a technology for measuring a nonlinear parameter of an object to be measured, and more particularly, to an apparatus and method for measuring a nonlinear parameter of an object to be measured.
Type:
Application
Filed:
November 4, 2013
Publication date:
November 12, 2015
Applicant:
KOREA RESEARCH INSTITUTE OF STANDARDS AND SCIENCE
Inventors:
Dae Cheol Seo, Seung Hyun Cho, Choon Su Park, Seung Seok Lee, Young Min Seong
Abstract: Provided is a ?E measuring device minimizing external magnetic disturbance, more particularly, a ?E measuring device measuring a change (?E) in elastic modulus under a magnetic field by removing a bias effect by the earth's magnetic field and a magnetic tool and device and using a magneto acoustic resonance method. With the ?E measuring device, a space minimizing external magnetic disturbance using three-axis Helmholtz coils is provided and the ?E measuring device having a plurality of coil structures is inserted into the space, thereby making it possible to minimize external magnetic field disturbance.
Type:
Grant
Filed:
November 3, 2010
Date of Patent:
September 8, 2015
Assignee:
Korea Research Institute of Standards and Science
Inventors:
Kwon Sang Ryu, Soo Young Park, Seung Hoon Nahm, Young Il Kim
Abstract: The present invention pertains to a device and a method for measuring a via hole of a silicon wafer, wherein it is possible to precisely measure the depth of the via hole without damaging the wafer. Broadband infrared light is radiated to a silicon wafer which has a superior light transmission property, so that the depth of the via hole may be measured from the light which is reflected from each boundary surface of the wafer and the interference signal of reference light. The via hole measuring device according to the present invention includes: a light source unit for generating broadband infrared light; and an interferometer for radiating the light generated from the light source unit to a silicon wafer, so as to measure the depth of a via hole formed on the wafer according to the spectrum period of the interference signal of the light, which is reflected from the silicon wafer.
Type:
Grant
Filed:
June 24, 2011
Date of Patent:
September 1, 2015
Assignee:
KOREA RESEARCH INSTITUTE OF STANDARDS AND SCIENCE
Inventors:
Jong Han Jin, Jae Wan Kim, Jong Ahn Kim, Chu-Shik Kang
Abstract: Provided is a preparation method of a free fatty acid particle dispersion solution, the preparation method including: a) dissolving fatty acid in a solvent to prepare a fatty acid solution; and b) injecting the fatty acid solution in a non-solvent having miscibility with the solvent to prepare a free fatty acid particle dispersion solution.
Type:
Grant
Filed:
November 7, 2013
Date of Patent:
August 25, 2015
Assignee:
KOREA RESEARCH INSTITUTE OF STANDARDS AND SCIENCE
Abstract: The present invention relates to a method for expressing, extracting and refining recombinant human growth hormone (hGH). More particularly, the present invention relates to a method for the intracellular expression of a target protein with minimizing the formation of insoluble inclusion bodies during the mass production of the protein in Escherichia coli system. The present invention also relates to a method for extracting and refining the target protein, particularly human growth hormone, with maximizing its solubility during the extraction and with providing a high yield but without losing the biological activity of the target protein.
Type:
Application
Filed:
March 13, 2015
Publication date:
July 30, 2015
Applicant:
KOREA RESEARCH INSTITUTE OF STANDARDS AND SCIENCE
Inventors:
Jun-Hyuk Choi, Sook-Kyung Kim, Minji Kim
Abstract: A magnetostrictive phased array transducer for transducing shear horizontal bulkwaves including a plurality of magnetostrictive members each having a bottom surface of a plate-shaped structure made of a ferromagnetic material, which is mounted to be adhered closely to the surface of a mounting place; an insulator disposed on a side surface of each magnetostrictive member; a meander coil having a plurality of coil lines extended in the direction parallel with the bottom surface on each insulator, wherein adjacent coil lines are connected so that current flows in the opposite directions to each other, thereby generating a dynamic magnetic field with respect to each magneto strictive member; and a magnet mounted to generate a static magnetic field perpendicular to the dynamic magnetic field. When the current is supplied to the meander coil, a plurality of magnetostrictive members generate a plurality of shear horizontal bulkwaves while being deformed by the magnetostriction effect.
Type:
Grant
Filed:
November 8, 2012
Date of Patent:
July 7, 2015
Assignee:
KOREA RESEARCH INSTITUTE OF STANDARDS AND SCIENCE
Inventors:
Seung Hyun Cho, Bong Young Ahn, Tae Hoon Heo
Abstract: Provided is a spatial phase shifting interferometer using a multi wavelength. More particularly, provided is a spatial phase shifting interferometer using a multi wavelength capable of more rapidly measuring a precise shape of a measurement object by simultaneously oscillating laser having different wavelengths and passing the oscillated laser through a beam splitter and a lens to analyze an interference fringe of the measurement object.
Type:
Grant
Filed:
November 2, 2012
Date of Patent:
April 28, 2015
Assignees:
Korea Research Institute of Standards and Science, Micro Motion Technology Co., Ltd.
Inventors:
Jae Wan Kim, Jong Ahn Kim, Dong-Won Lee
Abstract: Provided is a fusion measurement apparatus which increases or maximizes the reliability of a measurement. The fusion measurement apparatus includes an atomic microscope for measuring a surface of a substrate at an atomic level, an electron microscope for measuring the atomic microscope and the substrate, and at least one electrode which distorts the path of a secondary electron on the substrate covered by a cantilever of the atomic microscope so that the secondary electron proceeds to an electron detector of the electron microscope.
Type:
Grant
Filed:
June 24, 2011
Date of Patent:
April 14, 2015
Assignee:
Korea Research Institute of Standards and Science
Inventors:
Byong Chon Park, Ju Youb Lee, Woon Song, Jin Ho Choi, Sang Jung Ahn, Joon Lyou, Won Young Song, Jae Wan Hong, Seung Hun Baek
Abstract: Provided are a method of forming an upper electrode of a nanowire array and a nanowire array having an upper electrode formed thereon. The method includes a step of placing a polymeric thin film layer, a step of pressing, a step of treating a mixed solution, a step of etching, and a step of depositing an electrode material, such that the upper electrode is reliably formed in a state in which the polymeric thin film layer is formed on a portion of the nanowire, thereby making it possible to implement various nano-devices based on the nanowire array aligned on a substrate having a large area.
Type:
Application
Filed:
December 21, 2012
Publication date:
March 26, 2015
Applicant:
KOREA RESEARCH INSTITUTE OF STANDARDS AND SCIENCE
Abstract: The present invention relates to an apparatus for quantifying the binding and dissociation kinetics of molecular interactions of small molecular bio materials with high sensitivity almost without the influence of a change in the reflective index resulting from a buffer solution by making polarized incident light incident on the binding layer of a bio material, formed in a thin dielectric film, so that the polarized incident light satisfies a p-wave non-reflecting condition and a quantifying method using the same.
Type:
Grant
Filed:
October 29, 2010
Date of Patent:
January 27, 2015
Assignee:
Korea Research Institute of Standards and Science
Abstract: Provided are a signal processing apparatus and a signal processing method. The signal processing method include receiving a serial signal including an information frame including channel information and data information of a corresponding channel, extracting a clock signal from the serial signal, generating a load signal when a clock count reaches a maximum clock count by calculating the clock signal; converting the serial signal to a parallel signal according to the load signal, and changing the maximum clock count by comparing parallel-converted parallel channel information with a load count indicating the number of local signals.
Type:
Grant
Filed:
November 30, 2012
Date of Patent:
January 27, 2015
Assignee:
Korea Research Institute of Standards and Science
Inventors:
Jin Mok Kim, Hyukchan Kwon, Yong Ho Lee, Ki Woong Kim
Abstract: Provided is a signal processing device including: a digital signal detector outputting an inputted serial digital signal; a clock signal generator generating a clock signal on the basis of the serial digital signal; a chip selection signal generator generating a chip selection signal for selecting a chip by using at least one signal of the clock signal and the serial digital signal; and an initializer detecting an initializing signal included in the serial digital signal and generates a reset signal for initializing an operation of the clock signal generator and the chip selection signal generator on the basis of the initializing signal.
Type:
Application
Filed:
July 7, 2014
Publication date:
January 22, 2015
Applicant:
KOREA RESEARCH INSTITUTE OF STANDARDS AND SCIENCE
Inventors:
Jinmok KIM, Hyukchan KWON, Yongho LEE, Ki Woong KIM, Kwonkyu YU
Abstract: The present invention relates to a method for screening and discovering bioactive materials using specifically selected protein domains interacting with specific intracellular proteins, and more particularly, to (1) a screening method including confirmation of changes in biological activities by introducing a specific protein domain into microorganisms or animal and plant cells and (2) a screening method including confirmation of changes in biological activities after introducing the specific protein domains into a number of microorganisms or animal and plant cells. Via this method, according to the present invention, it is possible that the selected protein domains can be used to develop novel antibiotic agents with antimicrobial activity effective on bacteria resistant to conventional antibiotics while requiring less genetic information compared with a conventional drug which targets specific genes.
Type:
Grant
Filed:
May 23, 2006
Date of Patent:
December 9, 2014
Assignee:
Korea Research Institute of Standards and Science