Patents Assigned to Korea University Industry& Academy Cooperation Foundation
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Patent number: 7511167Abstract: Two-photon dyes for real-time imaging of lipid rafts are provided. The two-photon dyes emit fluorescence with high intensity in the environments of cell membranes and can be used to clearly discriminate the hydrophobic and hydrophilic domains of the cell membranes. Therefore, the use of the two-photon dyes enables satisfactory imaging of actual lipid raft domains. In addition, since the two-photon dyes show no cytotoxicity, they can be suitably used in bioimaging applications, for example, real-time imaging of lipid rafts over a long period of time.Type: GrantFiled: June 29, 2007Date of Patent: March 31, 2009Assignee: Korea University Industry and Academy Cooperation FoundationInventor: Bong-Rae Cho
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Publication number: 20090017489Abstract: The present invention relates to a composition for modulating the activation of Nurr1, the composition comprising an agonist or an antagonist of a dopamine D2 receptor, methods for modulating the activation of Nurr1 by the dopamine D2 receptor, a method and composition for treating Nurr1-related diseases using the dopamine D2 receptor, and methods for screening a modulator of a dopamine D2 receptor of a test compound. Accordingly, the activation of Nurr1 can be modulated by treating the dopaminergic neurons with the agonist or the antagonist of the dopamine D2 receptor, thereby enhancing or inhibiting generation of the dopaminergic neurons.Type: ApplicationFiled: June 22, 2006Publication date: January 15, 2009Applicant: Korea University Industry And Academy Cooperation FoundationInventors: Ja hyun Baik, Sung yul Kim
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Patent number: 7440406Abstract: An apparatus for displaying network status includes a network traffic collection unit, a network status display unit and a first attack type determination unit. The network traffic collection unit analyzes packets collected from an external communication network, and outputs connection information including a source Internet Protocol (IP) address, a destination IP address and a destination port number. The network status display unit receives the connection information transmitted from the network traffic collection unit for a predetermined period, and displays the connection information in a coordinate point data form on a three-dimensional rectangular coordinate system whose three axes are assigned to a source IP address, a destination IP address and a destination port number, respectively.Type: GrantFiled: December 29, 2004Date of Patent: October 21, 2008Assignee: Korea University Industry & Academy Cooperation FoundationInventors: Hee-Jo Lee, Hyo-Gon Kim, Sae-Woong Bahk
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Publication number: 20080196341Abstract: A modular column system and a method of constructing the same are constructed by stacking at least one precast unit between a foundation section and a coping section. The precast unit makes use of an internally confined hollow column unit fabricated in advance, and joint sections between the precast units are firmly formed. Thereby, the modular column system can realize a short construction period and economy because reinforcement bars and forms are not used, as well as high resistance to bending moment and reduction in cross section and self-weight of the precast unit, and thus the modular column system can provide easier and more economical assembly, and prevent brittle fracture of the joint section between the precast units.Type: ApplicationFiled: February 15, 2007Publication date: August 21, 2008Applicant: Korea University Industry and Academy Cooperation FoundationInventors: Young Jong Kang, Taek Hee Han, Sang Yun Han
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Publication number: 20080190224Abstract: The present invention provides a safety unit comprising: a case; a rotary linkage disposed at one end thereof at the outside of the case and rotatably mounted at the other end thereof to the case; a force transfer shaft mounted to one side of the rotary linkage in such a fashion as to be oriented perpendicular to the rotating plane of the rotary linkage; a crank linkage rotatably mounted at one end thereof to the inner side of the case and adapted to abut against the force transfer shaft at the outer circumferential edge thereof so as to be transferred with an external force to be rotatably moved; and a support means rotatably connected to the other end of the crank linkage and adapted to allow for the rotation of the crank linkage when an external force having a value larger than a predetermined threshold value is exerted to the rotary linkage.Type: ApplicationFiled: August 11, 2006Publication date: August 14, 2008Applicant: KOREA UNIVERSITY INDUSTRY AND ACADEMY COOPERATION FOUNDATIONInventors: Jae-Bok Song, Jung-Jun Park, Byeong-Sang Kim
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Publication number: 20080152626Abstract: A method for activating a CD8 T cell includes separating CD8 T cells and cultivating them in vitro with a culture broth containing cytokines such as GM-CSF, IFN-?, TNF-?, lectin, IL-2 and IL-4. Also provided is a therapeutic composition for preventing or treating infectious viral diseases, which includes the CD8 T cell activated by the above-noted method.Type: ApplicationFiled: January 20, 2006Publication date: June 26, 2008Applicant: Korea University Industry and Academy Cooperation FoundationInventors: Yong-Keun Park, Won-Suck Yoon
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Publication number: 20080120735Abstract: Disclosed herein are an Arabidopsis gene (AtLEJ1), acting as an inhibitor of the biosynthesis of the phytohormones jasmonic acid and ethylene, and a method for producing a male sterile transgenic plant using the same. The gene guarantees stable male sterile strains which need no maintainers for the maintenance thereof. Also, the transgenic plants comprising the gene can be readily restored to a fertile phenotype merely through hormonal treatment. Although the preferred embodiments of the present invention have been disclosed for illustrative purposes, those skilled in the art will appreciate that various modifications, additions and substitutions are possible, without departing from the scope and spirit of the invention as disclosed in the accompanying claims.Type: ApplicationFiled: April 3, 2007Publication date: May 22, 2008Applicant: Korea University Industry and Academy Cooperation FoundationInventors: Jeong Sheop Shin, Kwang Wook Jung, Kyoung Shin Yoo, Mei Hua Cui, Yun Young Kim, Sung Han Ok
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Publication number: 20080071106Abstract: Two-photon dyes for real-time imaging of lipid rafts are provided. The two-photon dyes emit fluorescence with high intensity in the environments of cell membranes and can be used to clearly discriminate the hydrophobic and hydrophilic domains of the cell membranes. Therefore, the use of the two-photon dyes enables satisfactory imaging of actual lipid raft domains. In addition, since the two-photon dyes show no cytotoxicity, they can be suitably used in bioimaging applications, for example, real-time imaging of lipid rafts over a long period of time.Type: ApplicationFiled: June 29, 2007Publication date: March 20, 2008Applicant: Korea University Industry and Academy Cooperation FoundationInventor: Bong-Rae Cho
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Publication number: 20070283457Abstract: Disclosed herein are a sweetpotato expansin cDNA (IbExpansin), a plant transformation vector carrying the same, and a transgenic plant comprising the vector. The transgenic Arabidopsis, prepared using the IbExpansin cDNA, outgrows the wild-type, thereby increasing in size and seed production up to three times. Thus, the gene is useful in the generation of highly productive transgenic plants for improvement in biomass and/or seed production.Type: ApplicationFiled: March 30, 2007Publication date: December 6, 2007Applicant: Korea University Industry and Academy Cooperation FoundationInventors: Jung Myung Bae, Seol Ah Noh, Sun Hee Park, Man Sup Kwak, Jeong Sheop Shin, Kyung Hee Paek
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Patent number: 7273757Abstract: The present invention relates to a recombinant vector comprising MJ1 gene coding an integrase derived from Enterococcus temperate bacteriophage ? FC1 and an integration method using the vector. More particularly, the present invention relates to a recombinant vector comprising MJ1 gene which can make a site-specific integration in the human cell independently without other factors but not cause an excision and an integration method using the vector. Therefore, the present invention can be very useful in gene therapy in mammalian animal.Type: GrantFiled: June 21, 2005Date of Patent: September 25, 2007Assignee: Korea University Industry and Academy Cooperation FoundationInventors: Hyo Ihl Chang, Hyo Sook Choi
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Publication number: 20070189416Abstract: An Orthogonal Spatial Multiplexing (OSM) apparatus and method in a closed-loop Multiple Input Multiple Output-Orthogonal Frequency Division Multiplexing (MIMO-OFDM) system are provided. In the OSM method, a basic signal model is set and transmission symbols are encoded. A real-valued system model corresponding to the basic signal model is obtained. To achieve orthogonality, rotations angles are calculated and are applied to the encoded transmission symbols.Type: ApplicationFiled: January 19, 2007Publication date: August 16, 2007Applicants: SAMSUNG ELECTRONICS CO., LTD., Korea University Industry and Academy Cooperation FoundationInventors: Young-Soo Kim, Dong-Jun Lee, Jung-Hoon SUH, Kyung-Hun Jang, Hyo-Sun Hwang, In-Kyu Lee, Heun-Chul Lee
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Patent number: 7141424Abstract: An isolated solely pollen-specific promoter derived from Arabidopsis comprise a nucleotide sequence of Arabidopsis PLA2-? gene. The novel promoter has specific roles in particular organs and at particular developmental stages, such as in mature flowers, and can be used in the production of hybrid seeds using male sterility techniques.Type: GrantFiled: October 29, 2004Date of Patent: November 28, 2006Assignee: Korea University Industry& Academy Cooperation FoundationInventors: Jeong Sheop Shin, Beung Tae Ryu, Sung Chul Bahn, Hae Jin Kim
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Patent number: 7022875Abstract: A novel antibiotic thiobutacin, obtainable from Lechevalieria aerocolonigenes strain VK-A9, and antifungal and antioomycete compositions comprising thiobutacin as an active ingredient for control of plant diseases, e.g., those attributable to pathogens such as Phytophthora capsici and Botrytis cinerea.Type: GrantFiled: January 13, 2004Date of Patent: April 4, 2006Assignee: Korea University Industry and Academy Cooperation FoundationInventors: Byung Kook Hwang, Jung Yeop Lee