Patents Assigned to KOREA UNIVERSITY RESEARCH AND BUSINESSE FOUNDATION
  • FLAVIN MONONUCLEOTIDE-BINDING PROTEIN VARIANTS HAVING IMPROVED FLUORESCENCE INTENSITY DERIVED FROM ARABIDOPSIS THALIANA
    Publication number: 20220267387
    Abstract: The present invention relates to flavoprotein improved LOV (iLOV) variants that exhibit enhanced fluorescence intensity compared to iLOV. The present invention also relates to a method for screening any of the iLOV variants. The iLOV variants of the present invention are useful in determining whether target proteins are expressed, irrespective of the presence of oxygen, and isolating and purifying the expressed target proteins due to their enhanced fluorescence intensity and quantum yield compared to existing LOV or iLOV proteins.
    Type: Application
    Filed: September 29, 2020
    Publication date: August 25, 2022
    Applicants: KOREA UNIVERSITY RESEARCH AND BUSINESSE FOUNDATION, KOOKMIN UNIVERSITY INDUSTRY ACADEMY COOPERATION FOUNDATION
    Inventors: Sang Taek JUNG, Sang Hwan KO, Bora HWANG, Jung-Hyun NA