Patents Assigned to Kosan Bioscience
  • Sorangium polyketide synthases and encoding DNA therefor
    Patent number: 6280999
    Abstract: Novel Sorangium polyketide synthases, and domains thereof, and polynucleotides encoding therefor. Additionally, chimeric polyketide synthases that include domains, or subsets of domains, patterned on said novel polyketide synthases. Methods to prepare polyketide combinatorial libraries are described, as are recombinant host cells in which polyketides are produced.
    Type: Grant
    Filed: August 31, 1998
    Date of Patent: August 28, 2001
    Assignee: Kosan Bioscience
    Inventors: Claes Gustafsson, Mary C. Betlach, Gary Ashley, Bryan Julien, Rainer Ziermann
  • Sorangium polyketide synthase
    Patent number: 6090601
    Abstract: Domains of epothilone polyketide synthase, and polynucleotides encoding therefor. Additionally, chimeric polyketide synthases that include domains, or subsets of domains, patterned on epothilone polyketide synthase. Methods to prepare epothilone in pharmaceutically useful quantitites are described, as are methods to prepare polyketide combinatorial libraries.
    Type: Grant
    Filed: January 23, 1998
    Date of Patent: July 18, 2000
    Assignee: Kosan Bioscience
    Inventors: Claes Gustafsson, Mary C. Betlach