Abstract: The invention provides compositions, compounds, formulations, and methods for treating HPV infections including pre-malignant infections and cancer. Compounds that covalently bind to the HPV E6 protein are disclosed.
Type:
Grant
Filed:
November 30, 2022
Date of Patent:
March 19, 2024
Assignees:
The Trustees of Indiana University, Kovina Therapeutics, Inc.
Inventors:
Elliot J. Androphy, Samy O. Meroueh, Zhijian Lu
Abstract: Compositions and methods are provided for treating HPV infections including pre-malignant and cancers. Compounds that specifically bind to the HPV E6 protein and inactivate the protein are disclosed.
Type:
Grant
Filed:
September 26, 2022
Date of Patent:
January 23, 2024
Assignees:
THE TRUSTEES OF INDIANA UNIVERSITY, KOVINA THERAPEUTICS, INC
Inventors:
Elliot J. Androphy, Samy Meroueh, Zhijian Lu, Anne Rietz
Abstract: Compositions and methods are provided for treating HPV infections including pre-malignant and cancers. Compounds that specifically bind to the HPV E6 protein and inactivate the protein are disclosed.
Type:
Grant
Filed:
January 19, 2022
Date of Patent:
April 18, 2023
Assignees:
THE TRUSTEES OF INDIANA UNIVERSITY, KOVINA THERAPEUTICS, INC.
Inventors:
Elliot J. Androphy, Samy Meroueh, Zhijian Lu