Patents Assigned to Kowa Company, Limited
  • Patent number: 6489991
    Abstract: A TV camera system comprises a TV camera unit and a lens unit that can be attached to, and detached from, the TV camera unit. The lens unit includes an iris mechanism the operation of which is controlled by signals from the TV camera unit. The TV camera unit and lens unit are electrically connected by a cable that also includes an amplifier section that amplifies the signals sent from the TV camera unit to control the operation of the iris.
    Type: Grant
    Filed: January 23, 2001
    Date of Patent: December 3, 2002
    Assignee: Kowa Company Limited
    Inventor: Makoto Ishida
  • Patent number: 5575285
    Abstract: An apparatus for non-invasively measuring the oxygen saturation in the blood of a subject comprises light sources for irradiating a sample of blood in tissue with at least a first light beam and a second light beam having different wavelengths. A switching device drives the light sources and sequentially switches the irradiation of the sample of blood between the first and second laser beams. A photoelectric detector detects light transmitted through or reflected from the sample of blood and provides an electrical output signal indicative of the intensity of the detected light. A converter converts the electrical output signal of the photoelectric detecting device to a power spectrum, and a processor processes the power spectrum and calculates the oxygen saturation of the sample of blood.
    Type: Grant
    Filed: December 14, 1994
    Date of Patent: November 19, 1996
    Assignee: Kowa Company Limited
    Inventors: Satohiko Takanashi, Tetsuya Yamamoto, Tsuyoshi Watanabe, Muneharu Ishikawa
  • Patent number: 5184157
    Abstract: An ophthalmic measurement apparatus is provided in which a laser beam is converged at a selected point in a measurement zone within an eye and light scattered therefrom is photoelectrically detected via a measurement mask having an aperture of a prescribed size for ophthalmic measurement. During alignment the measurement zone is scanned at high speed by the laser beam with the same scanning width as the scanning width used during measurement. This makes it possible to observe any harmful light rays that will actually appear during measurement at those settings and to align the apparatus so that the harmful light rays do not come within the limiting aperture of the measurement mask, thereby enabling measurement to be conducted under optimum conditions.
    Type: Grant
    Filed: May 30, 1990
    Date of Patent: February 2, 1993
    Assignee: Kowa Company Limited
    Inventors: Tadashi Ichihashi, Koichi Akiyama
  • Patent number: 5013146
    Abstract: Disclosed is an ophthalmological measurement apparatus in which a laser beam is directed into an eye under examination and a measurement value is output on the basis of the state of scattering of the laser beam within the eye. An alignment index projector is provided for forming an alignment index for use in judging alignment between the apparatus and the eye under examination, whose relative position is controlled to cause light scattering points produced at the eye by the laser beam and the light of the alignment index image to assume predetermined positions within the field of an observation. The apparatus can be used for measuring protein concentration in the anterior chamber of the eye or as a split lamp microscope and enables easy alignment between itself and the eye being examined.
    Type: Grant
    Filed: August 18, 1989
    Date of Patent: May 7, 1991
    Assignee: Kowa Company Limited
    Inventor: Koichi Akiyama
  • Patent number: 4854694
    Abstract: An eye fixation monitor for ophthalmological examination is provided which is capable of automatically monitoring the eye fixation without the ophthalmologist being required to initialize the eye fixation value. The eye fixation is monitored using deviation signals derived on the basis of the eye image formed on photoelectric transducers. The eye fixation monitor is provided with means for inducing the patient to assume the eye fixation state, and to resume the monitoring automatically after the examination has been interrupted by excessive deviation of the line of sight from the eye fixation target.
    Type: Grant
    Filed: June 8, 1987
    Date of Patent: August 8, 1989
    Assignee: Kowa Company Limited
    Inventors: Takashi Hirano, Atsushi Kojima
  • Patent number: 4525347
    Abstract: An antiinflammatory analgesic ointment comprising: (a) an antiinflammatory amount of indomethacin; (b) a medium consisting of a hydroxy compound in the range of from 15 to 85% by weight, water in the range of 30 to 55% by weight and a gelating agent being present in an amount sufficient to effect gelation of said ointment and selected from the group consisting of a cellulose compound and a carboxyvinyl polymer which has been neutralized with aqueous ammonia or an amine; (c) an adjuvant being present in the range of from 0.5 to 5% by weight and selected from the group consisting of a C.sub.1 -C.sub.5 alcohol ester of a C.sub.4 -C.sub.14 monocarboxylic acid and a C.sub.1 -C.sub.3 alcohol diester of a C.sub.4 -C.sub.
    Type: Grant
    Filed: February 22, 1983
    Date of Patent: June 25, 1985
    Assignee: Kowa Company Limited
    Inventors: Toshio Inagi, Toyojiro Muramatsu, Hidetaka Nagai
  • Patent number: 4443603
    Abstract: A piperazine derivartive represented by the following formula: ##STR1## wherein R.sub.1 : an indolyl group which may optionally be substituted by one or more lower alkyl and/or lower alkoxy groups, naphthyl group which may optionally be saturated partially with 2 or 4 hydrogen atoms, or phenyl or cyclohexyl group which may optionally be substituted by one or more lower alkyl groups;A: a single bond or alkylene group;P: a single bond or vinylene group;Q: an -O-alkylene group or -NH-alkylene group when P is a single bond, or a single bond when P is a vinylene group; andR.sub.2 : a lower alkyl, morpholino-lower alkyl, morpholino-carbonyl lower alkyl, piperidinocarbonyl lower alkyl, piperazinocarbonyl lower alkyl or lower alkylaminocarbonyl lower alkyl group, or an acid addition salt thereof is a proteolytic enzyme inhibitor.
    Type: Grant
    Filed: May 24, 1982
    Date of Patent: April 17, 1984
    Assignee: Kowa Company Limited
    Inventors: Setsuro Fujii, Eizou Hattori, Mitsuteru Hirata, Koichiro Watanabe, Hiroshi Ishihama
  • Patent number: 4309414
    Abstract: An antiinflammatory analgesic gelled ointment is disclosed which comprises indomethacin, a medium consisting of a glycol, alcohol and water, a gelling agent selected from cellulose and a carboxyvinyl polymer which has been neutralized with an amine, and water sufficiently enough to make up the balance. Such gelled ointment has an excellent antiinflammatory activity.
    Type: Grant
    Filed: October 23, 1979
    Date of Patent: January 5, 1982
    Assignee: Kowa Company Limited
    Inventors: Toshio Inagi, Toyojiro Muramatsu, Hidetaka Nagai
  • Patent number: 4290954
    Abstract: A tetrahydroxanthone derivative represented by the general formula: ##STR1## wherein R is a hydrogen atom, a hydroxyl, cyano, lower alkyl, lower alkoxy, lower acyloxy, benzoyloxy or tetrazolyl group, or ##STR2## (R.sub.3 is a hydrogen atom, R.sub.4 is a hydrogen atom, a phenyl group which may be optionally substituted, or a tetrazolyl group; or R.sub.3 and R.sub.4 commonly form a ring together with the adjacent nitrogen atom and another nitrogen atom or an oxygen atom); R.sub.1 is a hydrogen or halogen atom, a lower alkyl, cyano, carboxyl or tetrazolyl group, or ##STR3## (R.sub.5 is a hydrogen atom, R.sub.6 is a phenyl group which may be optionally substituted, or a tetrazolyl group; or R.sub.5 and R.sub.6 commonly form a ring together with the adjacent nitrogen atom and an oxygen atom); and R.sub.2 is a hydrogen or halogen atom, or a lower alkyl group; with the proviso that neither R nor R.sub.1 is a hydrogen atom; when R is --CONH.sub.2, R.sub.1 and R.sub.
    Type: Grant
    Filed: October 30, 1979
    Date of Patent: September 22, 1981
    Assignee: Kowa Company Limited
    Inventors: Kazuhiro Onogi, Hisashi Kunieda, Kiyoshi Kawamura, Masami Shiratsuchi, Masahiko Nagakura, Naoki Machida, deceased, by Takayasu Miwa, heir
  • Patent number: 4256631
    Abstract: The specification describes an economical process for the preparation of immunoglobulin for intravenous administration. An immunoglobulin can be, in accordance with the process, purified by a combination of a fractional precipitation method and an affinity chromatography. As a precipitant, divalent or trivalent metal salts are used and a complex of human IgG and a polyhydroxy polymeric compound is employed as an adsorbent. Purified immunoglobulin contains little or no aggregated or partially denatured globulin which is believed to cause anaphylaxis when administered intravenously. Prior art techniques cannot economically provide immunoglobulin in such a purified form and only intramuscular injections were feasible. Intravenous administrations allow immunoglobulin to be dosed in a larger amount and to act much faster than intramuscular injections.
    Type: Grant
    Filed: March 18, 1980
    Date of Patent: March 17, 1981
    Assignee: Kowa Company, Limited
    Inventors: Nobuo Yokoo, Toshihito Mori