Patents Assigned to Kowa Company, Limited
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Patent number: 6489991Abstract: A TV camera system comprises a TV camera unit and a lens unit that can be attached to, and detached from, the TV camera unit. The lens unit includes an iris mechanism the operation of which is controlled by signals from the TV camera unit. The TV camera unit and lens unit are electrically connected by a cable that also includes an amplifier section that amplifies the signals sent from the TV camera unit to control the operation of the iris.Type: GrantFiled: January 23, 2001Date of Patent: December 3, 2002Assignee: Kowa Company LimitedInventor: Makoto Ishida
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Patent number: 5575285Abstract: An apparatus for non-invasively measuring the oxygen saturation in the blood of a subject comprises light sources for irradiating a sample of blood in tissue with at least a first light beam and a second light beam having different wavelengths. A switching device drives the light sources and sequentially switches the irradiation of the sample of blood between the first and second laser beams. A photoelectric detector detects light transmitted through or reflected from the sample of blood and provides an electrical output signal indicative of the intensity of the detected light. A converter converts the electrical output signal of the photoelectric detecting device to a power spectrum, and a processor processes the power spectrum and calculates the oxygen saturation of the sample of blood.Type: GrantFiled: December 14, 1994Date of Patent: November 19, 1996Assignee: Kowa Company LimitedInventors: Satohiko Takanashi, Tetsuya Yamamoto, Tsuyoshi Watanabe, Muneharu Ishikawa
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Patent number: 5184157Abstract: An ophthalmic measurement apparatus is provided in which a laser beam is converged at a selected point in a measurement zone within an eye and light scattered therefrom is photoelectrically detected via a measurement mask having an aperture of a prescribed size for ophthalmic measurement. During alignment the measurement zone is scanned at high speed by the laser beam with the same scanning width as the scanning width used during measurement. This makes it possible to observe any harmful light rays that will actually appear during measurement at those settings and to align the apparatus so that the harmful light rays do not come within the limiting aperture of the measurement mask, thereby enabling measurement to be conducted under optimum conditions.Type: GrantFiled: May 30, 1990Date of Patent: February 2, 1993Assignee: Kowa Company LimitedInventors: Tadashi Ichihashi, Koichi Akiyama
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Patent number: 5013146Abstract: Disclosed is an ophthalmological measurement apparatus in which a laser beam is directed into an eye under examination and a measurement value is output on the basis of the state of scattering of the laser beam within the eye. An alignment index projector is provided for forming an alignment index for use in judging alignment between the apparatus and the eye under examination, whose relative position is controlled to cause light scattering points produced at the eye by the laser beam and the light of the alignment index image to assume predetermined positions within the field of an observation. The apparatus can be used for measuring protein concentration in the anterior chamber of the eye or as a split lamp microscope and enables easy alignment between itself and the eye being examined.Type: GrantFiled: August 18, 1989Date of Patent: May 7, 1991Assignee: Kowa Company LimitedInventor: Koichi Akiyama
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Patent number: 4854694Abstract: An eye fixation monitor for ophthalmological examination is provided which is capable of automatically monitoring the eye fixation without the ophthalmologist being required to initialize the eye fixation value. The eye fixation is monitored using deviation signals derived on the basis of the eye image formed on photoelectric transducers. The eye fixation monitor is provided with means for inducing the patient to assume the eye fixation state, and to resume the monitoring automatically after the examination has been interrupted by excessive deviation of the line of sight from the eye fixation target.Type: GrantFiled: June 8, 1987Date of Patent: August 8, 1989Assignee: Kowa Company LimitedInventors: Takashi Hirano, Atsushi Kojima
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Patent number: 4525347Abstract: An antiinflammatory analgesic ointment comprising: (a) an antiinflammatory amount of indomethacin; (b) a medium consisting of a hydroxy compound in the range of from 15 to 85% by weight, water in the range of 30 to 55% by weight and a gelating agent being present in an amount sufficient to effect gelation of said ointment and selected from the group consisting of a cellulose compound and a carboxyvinyl polymer which has been neutralized with aqueous ammonia or an amine; (c) an adjuvant being present in the range of from 0.5 to 5% by weight and selected from the group consisting of a C.sub.1 -C.sub.5 alcohol ester of a C.sub.4 -C.sub.14 monocarboxylic acid and a C.sub.1 -C.sub.3 alcohol diester of a C.sub.4 -C.sub.Type: GrantFiled: February 22, 1983Date of Patent: June 25, 1985Assignee: Kowa Company LimitedInventors: Toshio Inagi, Toyojiro Muramatsu, Hidetaka Nagai
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Patent number: 4443603Abstract: A piperazine derivartive represented by the following formula: ##STR1## wherein R.sub.1 : an indolyl group which may optionally be substituted by one or more lower alkyl and/or lower alkoxy groups, naphthyl group which may optionally be saturated partially with 2 or 4 hydrogen atoms, or phenyl or cyclohexyl group which may optionally be substituted by one or more lower alkyl groups;A: a single bond or alkylene group;P: a single bond or vinylene group;Q: an -O-alkylene group or -NH-alkylene group when P is a single bond, or a single bond when P is a vinylene group; andR.sub.2 : a lower alkyl, morpholino-lower alkyl, morpholino-carbonyl lower alkyl, piperidinocarbonyl lower alkyl, piperazinocarbonyl lower alkyl or lower alkylaminocarbonyl lower alkyl group, or an acid addition salt thereof is a proteolytic enzyme inhibitor.Type: GrantFiled: May 24, 1982Date of Patent: April 17, 1984Assignee: Kowa Company LimitedInventors: Setsuro Fujii, Eizou Hattori, Mitsuteru Hirata, Koichiro Watanabe, Hiroshi Ishihama
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Patent number: 4309414Abstract: An antiinflammatory analgesic gelled ointment is disclosed which comprises indomethacin, a medium consisting of a glycol, alcohol and water, a gelling agent selected from cellulose and a carboxyvinyl polymer which has been neutralized with an amine, and water sufficiently enough to make up the balance. Such gelled ointment has an excellent antiinflammatory activity.Type: GrantFiled: October 23, 1979Date of Patent: January 5, 1982Assignee: Kowa Company LimitedInventors: Toshio Inagi, Toyojiro Muramatsu, Hidetaka Nagai
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Patent number: 4290954Abstract: A tetrahydroxanthone derivative represented by the general formula: ##STR1## wherein R is a hydrogen atom, a hydroxyl, cyano, lower alkyl, lower alkoxy, lower acyloxy, benzoyloxy or tetrazolyl group, or ##STR2## (R.sub.3 is a hydrogen atom, R.sub.4 is a hydrogen atom, a phenyl group which may be optionally substituted, or a tetrazolyl group; or R.sub.3 and R.sub.4 commonly form a ring together with the adjacent nitrogen atom and another nitrogen atom or an oxygen atom); R.sub.1 is a hydrogen or halogen atom, a lower alkyl, cyano, carboxyl or tetrazolyl group, or ##STR3## (R.sub.5 is a hydrogen atom, R.sub.6 is a phenyl group which may be optionally substituted, or a tetrazolyl group; or R.sub.5 and R.sub.6 commonly form a ring together with the adjacent nitrogen atom and an oxygen atom); and R.sub.2 is a hydrogen or halogen atom, or a lower alkyl group; with the proviso that neither R nor R.sub.1 is a hydrogen atom; when R is --CONH.sub.2, R.sub.1 and R.sub.Type: GrantFiled: October 30, 1979Date of Patent: September 22, 1981Assignee: Kowa Company LimitedInventors: Kazuhiro Onogi, Hisashi Kunieda, Kiyoshi Kawamura, Masami Shiratsuchi, Masahiko Nagakura, Naoki Machida, deceased, by Takayasu Miwa, heir
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Patent number: 4256631Abstract: The specification describes an economical process for the preparation of immunoglobulin for intravenous administration. An immunoglobulin can be, in accordance with the process, purified by a combination of a fractional precipitation method and an affinity chromatography. As a precipitant, divalent or trivalent metal salts are used and a complex of human IgG and a polyhydroxy polymeric compound is employed as an adsorbent. Purified immunoglobulin contains little or no aggregated or partially denatured globulin which is believed to cause anaphylaxis when administered intravenously. Prior art techniques cannot economically provide immunoglobulin in such a purified form and only intramuscular injections were feasible. Intravenous administrations allow immunoglobulin to be dosed in a larger amount and to act much faster than intramuscular injections.Type: GrantFiled: March 18, 1980Date of Patent: March 17, 1981Assignee: Kowa Company, LimitedInventors: Nobuo Yokoo, Toshihito Mori