Patents Assigned to Krenitsky Pharmaceuticals, Inc.
  • Substituted 5-alkynyl pyrimidines having neurotrophic activity
    Patent number: 7205297
    Abstract: The present invention relates to a series of novel substituted 5-alkynyl pyrimidines, pharmaceutical compositions which contain them, methods for their preparation, and their use in therapy, particularly in the treatment of neurodegenerative or other neurological disorders of the central and peripheral nervous systems, including age related cognitive disorders such as senility and Alzheimer's disease, nerve injuries, peripheral neuropathies, and seizure disorders such as epilepsy.
    Type: Grant
    Filed: July 20, 2001
    Date of Patent: April 17, 2007
    Assignee: Krenitsky Pharmaceuticals, Inc.
    Inventors: Lilia M. Beauchamp, Thomas A. Krenitsky, James L. Kelley
  • Neurotrophic substituted pyrimidines
    Patent number: 6916820
    Abstract: The present invention relates to a series of substituted pyrimidines, to pharmaceutical compositions which contain them, to methods for their preparation and to their use in therapy, particularly in the treatment of neurodegenerative or other neurological disorders of the central and peripheral nervous systems.
    Type: Grant
    Filed: April 6, 2000
    Date of Patent: July 12, 2005
    Assignee: Krenitsky Pharmaceuticals, Inc.
    Inventors: James L. Kelley, Thomas A. Krenitsky, Lilia M. Beauchamp
  • Neurotrophic substituted pyrimidines
    Patent number: 6583148
    Abstract: The present invention relates to novel derivatives of a series of substituted pyrimidines, to pharmaceutical compositions which contain them, to methods for their preparation and to their use in therapy, particularly in the treatment of neurodegenerative or other neurological disorders of the central and peripheral systems.
    Type: Grant
    Filed: April 8, 1999
    Date of Patent: June 24, 2003
    Assignee: Krenitsky Pharmaceuticals, Inc.
    Inventors: James L. Kelley, Thomas A. Krenitsky, Lilia M. Beauchamp
  • Substituted pyrimidine derivatives, their preparation and their use in the treatment of neurodegenerative or neurological disorders of the central nervous system
    Patent number: 6440965
    Abstract: The present invention relates to novel derivatives of a series of substituted pyrimidines, to pharmaceutical compositions which contain them, to methods for their preparation and to their use in therapy, particularly in the treatment of neurodegenerative or other neurological disorders of the central and peripheral systems.
    Type: Grant
    Filed: April 14, 2000
    Date of Patent: August 27, 2002
    Assignee: Krenitsky Pharmaceuticals, Inc.
    Inventors: James L. Kelley, Thomas A. Krenitsky, Lilia M. Beauchamp
  • Phenoxathin derivatives as inhibitors of monoamine oxidase
    Patent number: 6110961
    Abstract: The present invention provide phenoxathiin compounds useful in the prophylaxis and treatment of mental disorders, such as depression. The present invention also provides a method for treating a mammal having depression, anxiety or other conditions responsive to inhibition of MAO-A. A method of preparing the compounds of the present invention is also provided.
    Type: Grant
    Filed: March 11, 1999
    Date of Patent: August 29, 2000
    Assignee: Krenitsky Pharmaceuticals, Inc.
    Inventors: Helen Lyng White, deceased, Morton Harfenist, Eric Boros, Dennis Heyer