Abstract: The present invention relates to the requirements for specimen tracking and maintenance in a cabinet x-ray system incorporating an x-ray tube, an x-ray detector, and an optical camera for the production of blended images. Excised tissue specimens are amorphous and quickly loose anatomical registration at the margins. The current device provides for breast specimens for a variety of sizes to be maintained accurately while successive images are acquired. Additionally, the base of the unit contains an RFID tag which ensures proper identification of the sample. In particular, the invention relates to a system and method with corresponding apparatus for acquiring multiple images in succession while maintaining specimen geometry and ensuring the image information is correctly identified with the corresponding patient.