Patents Assigned to KUDA THERAPEUTICS, INC. - Justia Patents Search

Patents Assigned to KUDA THERAPEUTICS, INC.

Imidazopyridine and oxazolopyridine derivatives and analogs thereof, methods of preparation thereof, methods of HIF-2A pathway inhibition, and induction of ferroptosis

Patent number: 11447482

Abstract: Novel substituted imidazopyridine and oxazolopyridine compounds that are useful as inhibitors of HIF-2? and inducers of ferroptosis through perturbations in iron metabolism, synthetic methods for making said compounds, pharmaceutical compositions comprising the compounds, and methods of using the compounds and compositions to treat disorders associated with dysfunction of HIF-2? or iron metabolism.

Type: Grant

Filed: February 14, 2020

Date of Patent: September 20, 2022

Assignee: KUDA THERAPEUTICS, INC.

Inventors: Xiaohui Liu, Mei Yee Koh