Abstract: A wheelchair driving mechanism includes a driving disk fastened to either large wheel of a wheelchair by a circular table and a circular casing for moving the wheelchair with the hand, and a ratchet wheel mechanism for permitting the respective large wheel to be rotated by the driving disk in one direction only. A hand lever may be fastened to the driving disk for rotating the respective large wheel with less labor. An adjustable foot plate stand may be extended out of the respective hanger bracket to match with the hand lever in supporting the wheelchair for permitting the wheelchair to be rotated over an obstacle.