Patents Assigned to Kupat Holim Health Institution of the General Federation of Labor
  • Retinoyloxy (alkyl-substituted) methyl butyrates useful for the treatment of gastrointestinal disorders, cutaneous ulcers and wounds
    Patent number: 6043277
    Abstract: This invention relates to the novel compounds of Formula (I) and pharmaceutical compositions containing same, to methods of treating, preventing or ameliorating cancer and other proliferative diseases in a subject in need of such treatment comprising administering a compound of Formula (I) and pharmaceutically-acceptable salts and prodrugs thereof. ##STR1## The compounds of the invention are also useful in methods of ameliorating wrinkles, inducing wound healing, treating cutaneous ulcers and treating gastrointestinal disorders.
    Type: Grant
    Filed: October 6, 1997
    Date of Patent: March 28, 2000
    Assignees: Bar-Ilan University, Kupat Holim Health Institution of the General Federation of Labor
    Inventors: Ada Rephaeli, Abraham Nudelman
  • Retinoyloxy (alkyl-substituted) methyl butyrates useful for the treatment of cancer and other proliferative diseases
    Patent number: 6040342
    Abstract: This invention relates to the novel compounds of Formula (I) and pharmaceutical compositions containing same, to methods of treating, preventing or ameliorating cancer and other proliferative diseases in a subject in need of such treatment comprising administering a compound of Formula (I) and pharmaceutically-acceptable salts and prodrugs thereof. ##STR1## The compounds of the invention are also useful in methods of ameliorating wrinkles, inducing wound healing, treating cutaneous ulcers and treating gastrointestinal disorders.
    Type: Grant
    Filed: July 2, 1996
    Date of Patent: March 21, 2000
    Assignees: Bar-Ilan University, Kupat Holim Health Institution of the General Federation of Labor
    Inventors: Ada Rephaeli, Abraham Nudelman