Abstract: The present invention provides an artificial joint stem, an artificial joint stem component, and an artificial joint stem manufacturing method with which the amount of labor required in manufacturing is reduced, the strength can be increased through the suppression of stress concentration, and the degree of freedom in the shape is high. A stem includes a stem body portion and a porous portion that has a porous body and is bonded to the stem body portion. The stem body portion has an insertion portion arranged to be inserted into a medullary cavity of a femur. The porous portion is a tubular standalone portion formed by stacking layers of a biocompatible metal powder, and is arranged so as to surround a proximal portion of the insertion portion.

Abstract: The present invention provides a bearing material that is excellent in durability and is capable of maintaining wear resistance over a long period of time. The bearing material of the present invention is a high wear-resistance bearing material 10 for being used under a humid environment comprising: a base body 12 made of a polymer material having a methylene group; and a polymer layer 30 covering a bearing surface 16 of the substrate 12, the polymer layer 30 comprising polymer chains which have a phosphorylcholine group and are grafted from the bearing surface 16, wherein a phosphoric index of the sliding surface 16 which is calculated by dividing a peak intensity of phosphate group in an infrared spectrum measured on the sliding surface by a peak intensity of the methylene group therein is not less than 0.28.

Abstract: An object of the present invention is to provide a method of producing a bearing material having excellent wear-resistance and oxidation resistance. The method of producing a bearing material 10 according to the present invention comprises molding a substrate 12 containing a radical scavenger and a polymer material; washing at least a part 16 of the substrate 12 with a washing liquid; and grafting a polymer chain having a phosphorylcholine group from at least the part 16 of the surface after washing so as to form a polymer film 30 on at least the part of the surface.

Abstract: There is provided a dental implant which can prevent peri-implantitis and in which an affinity of a jawbone embedded portion embedded into the jawbone with the jawbone is not degraded. In a dental implant, at least a region of a gingiva contacting portion which is in contact with gingiva, is antibacterially treated, and an arithmetic average roughness Ra of an outer surface of the region is set to 2 ?m or less. At least the region of the gingiva contacting portion has antibacterial properties, and becomes such a surface texture that bacteria are less prone to attach to and stay in the region, and the region is prone to be in close contact with the gingiva.

Abstract: The object of the present invention is to provide a joint prosthesis, bearing material and a production method thereof, which suppresses wear in a sliding section and suppresses the production of abrasive powder even during repeated daily operation. To achieve the object, there is provided a biomaterial comprising: a substrate made of metal, alloy or ceramic; and a biocompatible material layer laminated on the substrate, wherein hydroxyl groups are formed on the substrate by surface-treating, while the biocompatible material layer comprises a polymer containing phosphorylcholine groups, the substrate and the biocompatible material layer are bound via a binder layer which is combined with the hydroxyl groups of the substrate and with the biocompatible material layer.

Abstract: It is an object, with regard to a configuration for forming a macromolecular layer on a surface of a base material of an artificial joint component, to achieve a size reduction, to accurately control ultraviolet irradiation intensity, to form a macromolecular layer having a uniform thickness, to suppress the influence of ultraviolet light on equipment and workers, and to make the occurrence of a malfunction unlikely. A film-producing device body forms a macromolecular layer in an inner surface of a base material of an artificial joint component, by means of photograft polymerization. The film-producing device body includes a plurality of ultraviolet LED elements and a work holder. On the work holder, solution containing macromolecular monomers is in contact with the inner surface of the base material. The ultraviolet LED elements emit ultraviolet light to a wider area than an area that each of the ultraviolet LED elements individually irradiates.

Abstract: An artificial knee joint comprising a femoral component and a tibial plate is provided. The femoral component includes a medial condyle, a lateral condyle, a first sliding surface for coupling the medial and lateral condyles, while leaving an opening therebetween, and a second sliding surface above the first sliding surface. The tibial plate includes a medial fossa, a lateral fossa, a post insertable into the opening, a third sliding surface which the first sliding surface contacts at a posterior surface of the post, and a fourth sliding surface which the second sliding surface contacts behind the post. The artificial knee joint is configured to move in a first sliding state in which the first sliding surface is in contact with the third sliding surface, or a second sliding state in which the second sliding surface is in contact with the fourth sliding surface, according to a flexion angle.

Abstract: The present invention provides a medical ceramic material with a color other than black or white, especially blue, with which it is possible to secure sufficient durability and to maintain a good appearance by sufficiently suppressing a color difference between before and after the irradiation of gamma-rays for sterilization. The medical ceramic material is formed using a composite material containing alumina and zirconia. The composite material contains cobalt oxide. The content of cobalt oxide is set to be 0.2 wt % to 1.0 wt % with respect to 100 wt % of the composite material excluding cobalt oxide.

Abstract: Provided is a bioimplant which is capable to inhibit the biofilm formation over a long period of time after an operation. The bioimplant of the present invention comprises a base material of metal, ceramic, or plastic and a thermal spraying film of a calcium phosphate-based material formed at least partially thereon and the silver concentration in the thermal-spray film is 0.05 wt % to 3.00 wt %.

Abstract: The present invention aims to obtain a surface modification member which is bonded successfully to an implant material in a method for bonding a surface modification member and an implant material by using a slurry containing metal powders. The present invention is a biocompatible metallic porous plate to be bonded to the surface of in vivo implant material, wherein the area ratio A of open holes (a) present on the surface of the side facing the implant material is less than the area ratio B of open holes (b) present on the surface of the side facing a living body; and the open holes (a) communicate through to the living body side. The biocompatible metallic porous plate is preferably produced by layered manufacturing.

Abstract: An artificial knee joint includes a femoral component and a tibial plate. The femoral component includes a first joint face disposed adjacent to a medial collateral ligament of a patient, and a second joint face disposed adjacent to a lateral collateral ligament of the patient. The first and second joint faces respectively have first and second medial pivot guide portions. A reference face extending orthogonal to the left-right direction is defined between the first and second joint faces. An amount ?D2 of decrease in a distance D2 between the second contact portion on the second medial pivot guide portion and the reference face in accordance with an increase per unit flexion angle is greater than an amount ?D1 of decrease in a distance D1 between the first contact portion on the first medial pivot guide portion and the reference face in accordance with the increase per unit flexion angle.

Abstract: The present invention is to provide a Co—Cr—Mo alloy excellent in mechanical properties such as yield strength and tensile strength. The present invention is a biocompatible Co—Cr—Mo alloy comprising, in mass %, more than 30% and not more than 36% of Cr, 5 to 8% of Mo, 0.20 to 0.65% of N, and the balance consisting of Co and inevitable impurities, and produced by layered manufacturing. The biocompatible Co—Cr—Mo alloy of the present invention preferably has a solidification structure of a dendrite structure and the primary arm spacing of the dendrite structure is not more than 5 ?m.

Abstract: Disclosed is a sliding member with excellent durability and capable of maintaining wear resistance over a long period of time. Further disclosed is an artificial joint member for which the film thickness of the polymer base material is reduced. Further disclosed is an artificial joint which is capable of demonstrating high lubricity, biocompatibility, and resistance to dislocation after introduction into the body. Further disclosed are a medical appliance material and a medical appliance which demonstrate excellent biocompatibility.

Abstract: The object of the present invention is to provide a joint prosthesis, bearing material and a production method thereof, which suppresses wear in a sliding section and suppresses the production of abrasive powder even during repeated daily operation. To achieve the object, there is provided a biomaterial comprising: a substrate made of metal, alloy or ceramic; and a biocompatible material layer laminated on the substrate, wherein hydroxyl groups are formed on the substrate by surface-treating, while the biocompatible material layer comprises a polymer containing phosphorylcholine groups, the substrate and the biocompatible material layer are bound via a binder layer which is combined with the hydroxyl groups of the substrate and with the biocompatible material layer.

Abstract: The object of the present invention is to provide a joint prosthesis, bearing material and a production method thereof, which suppresses wear in a sliding section and suppresses the production of abrasive powder even during repeated daily operation. To achieve the object, there is provided a biomaterial comprising: a substrate made of metal, alloy or ceramic; and a biocompatible material layer laminated on the substrate, wherein hydroxyl groups are formed on the substrate by surface-treating, while the biocompatible material layer comprises a polymer containing phosphorylcholine groups, the substrate and the biocompatible material layer are bound via a binder layer which is combined with the hydroxyl groups of the substrate and with the biocompatible material layer.

Abstract: The present invention is intended for improving the reliability of a strength proof test method for ceramic parts. The present invention is directed to a strength proof test method for making total inspection of ceramic parts, including: applying a prescribed load to the ceramic parts; and at the same time, making an acoustic emission measurement, in which the ceramic parts are considered as passing when the ceramic parts are not fractured in the test and the variation of acoustic emission energy is not more than a threshold.

Abstract: Provided is a bioimplant superior in antimicrobial action and safety in the body. The bioimplant according to the present invention comprises a base material of metal, ceramic, or plastic and a thermal spraying film of a calcium phosphate-based material formed at least partially thereon and the silver concentration in the thermal spraying film is 0.02 wt % to 3.00 wt %.

Abstract: A metal material for a bioimplant which is excellent in biointegration according to the present invention has a surface treated by sandblasting, and the surface has an average roughness Ra of 1 to 2.5 ?m and is made free from residual abrasive used in the sandblasting treatment by washing with water after the sandblasting treatment and the composition of the metal material surface does not change before and after the sandblasting treatment. According to the present invention, it is possible to provide a bioimplant metal material from which an abrasive used for sandblasting treatment can be easily removed by washing with water and which is excellent in biointegration to a bone or the like since having a good roughened surface and a production method thereof.

Abstract: The present invention provides a centrifugal separation-use device capable of maintaining a centrifugal separation-use container in a clean state easily at low cost even when centrifugal separation treatment is carried out using a centrifugal separator in an unclean field. A centrifugal separation-use device 1 for collecting a target component by subjecting a solution containing multiple components to centrifugal separation treatment comprises an inner container 10 having a cylindrical section 12 for accommodating the solution and a plug 14 for hermetically sealing the cylindrical section and configured so as to accommodate the solution in a hermetically sealed state, and an outer container 20 having a support section 22 for removably accommodating the cylindrical section and a delivery section 24 for exposing part of the inner container so that the inner container can be removed, and configured so as to accommodate the inner container in a hermetically sealed state.