Abstract: A method of preparing a hetero-branched cyclodextrin comprising a glucosyl or a maltosyl group side chain and a mannosyl group .alpha.-bonded to a hydroxyl group of the glucosyl group or the maltosyl group of the side chain, the method involving reacting a liquid containing a branched cyclodextrin having a glucosyl or maltosyl group as the side chain and an .alpha.-mannosyl compound with an .alpha.-mannosyl transfer enzyme.
Abstract: A hetero-branched cyclodextrin (CD) having a glucosyl or maltosyl group as the side chain, in which a mannosyl group is .alpha.-bonded to the hydroxyl group of the glucosyl group of the side chain; and a method of efficiently preparing the same by reacting a branched cyclodextrin with an .alpha.-mannosidase. The hetero-branched CDs are useful in various fields such as in drugs, foods and cosmetics.