Abstract: The present invention provides a novel crystalline form of [R—(R*,R*)]-2-(4-fluorophenyl)-?,?-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-heptanoic acid hemi-calcium salt (atorvastatin hemi-calcium salt) of the following formula 1, which is known to be useful as a drug, a hydrate thereof and a preparation method thereof:
Type:
Grant
Filed:
February 24, 2017
Date of Patent:
April 9, 2019
Assignee:
KYONGBO PHARM
Inventors:
Kyung Ju Lee, Hoe Joo Son, Doo Seong Choi, Sun Ho Chang, Do Yeon Oh
Abstract: The present invention provides a novel crystalline form of [R—(R*,R*)]-2-(4-fluorophenyl)-?,?-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-heptanoic acid hemi-calcium salt (atorvastatin hemi-calcium salt) of the following formula 1, which is known to be useful as a drug, a hydrate thereof and a preparation method thereof:
Type:
Application
Filed:
February 24, 2017
Publication date:
January 11, 2018
Applicant:
KYONGBO PHARM
Inventors:
Kyung Ju LEE, Hoe Joo SON, Doo Seong CHOI, Sun Ho CHANG, Do Yeon OH
Abstract: The present invention provides a novel crystalline form of [R—(R*,R*)]-2-(4-fluorophenyl)-?,?-dihydroxy-5-(1-mthylethyl)-3 -phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-heptanoic acid hemi-calcium salt (atorvastatin hemi-calcium salt) of the following formula 1, which is known to be useful as a drug, a hydrate thereof and a preparation method thereof:
Type:
Application
Filed:
December 13, 2013
Publication date:
April 10, 2014
Applicant:
KYONGBO PHARM
Inventors:
Kyung Ju LEE, Hoe Joo SON, Doo Seong CHOI, Sun Ho CHANG, Do Yeon OH
Abstract: The present invention provides a novel crystalline form of [R-(R*,R*)]-2-(4-fluorophenyl)-?,?-dihydroxy-5-(1-mthylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-heptanoic acid hemi-calcium salt (atorvastatin hemi-calcium salt) of the following formula 1, which is known to be useful as a drug, a hydrate thereof and a preparation method thereof:
Type:
Application
Filed:
November 20, 2013
Publication date:
March 20, 2014
Applicant:
KYONGBO PHARM
Inventors:
Kyung Ju Lee, Hoe Joo Son, Doo Seong Choi, Sun Ho Chang, Do Yeon Oh
Abstract: The present invention provides a novel crystalline form of [R-(R*,R*)]-2-(4-fluorophenyl)-?,?-dihydroxy-5-(1-mthylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-heptanoic acid hemi-calcium salt (atorvastatin hemi-calcium salt) of the following formula 1, which is known to be useful as a drug, a hydrate thereof and a preparation method thereof:
Type:
Application
Filed:
January 27, 2012
Publication date:
May 17, 2012
Applicant:
KYONGBO PHARM
Inventors:
Kyung Ju LEE, Hoe Joo SON, Doo Seong CHOI, Sun Ho CHANG, Do Yeon OH
Abstract: The present invention provides a novel crystalline form of [R—(R*,R*)]-2-(4-fluorophenyl)-?,?-dihydroxy-5-(1-mthylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrol-1-heptanoic acid hemi-calcium salt (atorvastatin hemi-calcium salt) of the following formula 1, which is known to be useful as a drug, a hydrate thereof and a preparation method thereof:
Type:
Application
Filed:
January 24, 2011
Publication date:
February 2, 2012
Applicant:
KYONGBO PHARM
Inventors:
Kyung Ju Lee, Hoe Joo Son, Doo Seong Choi, Sun Ho Chang, Do Yeon Oh