Patents Assigned to KYOWA PHARMACEUTICAL CO., LTD.
  • Publication number: 20040146558
    Abstract: An oral enteric-coated preparation of the present invention comprises a core containing an active ingredient unstable to acid, an intermediate film enveloping the core, and an enteric film further enveloping the intermediate film, and the intermediate film comprises a matrix sparsely soluble in water and water-soluble fine particles dispersed therein. The presence of the intermediate film consisting of the matrix sparsely soluble in water and the water-soluble fine particles between the outer enteric film and the core uniformizes the disintegration time of the intermediate film and thus suppresses a variation in the time to start releasing the active ingredient in the core.
    Type: Application
    Filed: January 28, 2003
    Publication date: July 29, 2004
    Applicant: KYOWA PHARMACEUTICAL CO., LTD.
    Inventors: Kenji Hirata, Masaki Mori