Patents Assigned to Kyto Biopharma, Inc.
  • Growth blocking agents
    Patent number: 7416728
    Abstract: There is disclosed anti-receptor and growth blocking agents to the vitamin B12/transcobalamin II receptor and binding sites. The anti-receptor and growth blocking agents antagonize or modulate the vitamin B12/transcobalamin II receptor or binding sites, causing cellular depletion of vitamin B12, thus inhibiting cell division or causing apoptosis. Anti-receptor and growth blocking agents of the present invention include proteins (such as antibodies and antibody derivatives), peptides and small organic molecules. In a preferred embodiment, the anti-receptor agent is an antibody to the vitamin B12/transcobalamin II receptor.
    Type: Grant
    Filed: October 1, 2004
    Date of Patent: August 26, 2008
    Assignees: Kyto Biopharma, Inc., State University of New York
    Inventors: A. Charles Morgan, Jr., Edward V. Quadros, Sheldon P. Rothenberg
  • Growth blocking agents
    Publication number: 20050169910
    Abstract: There is disclosed anti-receptor and growth blocking agents to the vitamin B12/transcobalamin II receptor and binding sites. The anti-receptor and growth blocking agents antagonize or modulate the vitamin B12/transcobalamin II receptor or binding sites, causing cellular depletion of vitamin B12, thus inhibiting cell division or causing apoptosis. Anti-receptor and growth blocking agents of the present invention include proteins (such as antibodies and antibody derivatives), peptides and small organic molecules. In a preferred embodiment, the anti-receptor agent is an antibody to the vitamin B12/transcobalamin II receptor.
    Type: Application
    Filed: October 1, 2004
    Publication date: August 4, 2005
    Applicants: Kyto Biopharma, Inc., State University of New York
    Inventors: A. Morgan, Edward Quadros, Sheldon Rothenberg