Abstract: A small molecule TNF-? inhibitor is disclosed. The compound has an activity of inhibiting the formation of a TNF-? homotrimer by specifically binding to the binding cavity of a TNF-? homodimer. A composition containing the compound as well as uses of the compound and the composition in preventing or treating autoimmune diseases and/or inflammatory diseases are disclosed. Extracellular inactivation of TNF-? through protein-protein interface destruction is the most innovative and effective method for alleviating chronic systemic inflammatory states, and TIM series compounds, which have better efficacy and lower toxicity than those of existing TNF inhibitors and have oral bioavailability, can be effectively used as leading anti-inflammatory molecules.

Abstract: Provided are an ultraviolet emitting optical device and an operating method thereof. The ultraviolet emitting optical device includes a substrate, a first encapsulation layer, an active layer and a second encapsulation layer sequentially stacked on the substrate, a first electrode layer between the first encapsulation layer and the active layer, a second electrode layer between the active layer and the second encapsulation layer, and color centers provided in the active layer, wherein the active layer includes hexagonal boron nitride (hBN), wherein the color centers are configured to emit light in an ultraviolet wavelength range.

Abstract: Disclosed are an image encoding method using a skip mode and a device using the method. The image encoding method may comprise the steps of: judging whether there is residual block data of a prediction target block on the basis of predetermined data indicating whether residual block data has been encoded; and, if there is residual block data, restoring the prediction target block on the basis of the residual block data and an intra-screen predictive value of the prediction target block. Consequently, encoding and decoding efficiency can be increased by carrying out the encoding and decoding of screen residual data only for prediction target blocks where there is a need for a residual data block in accordance with screen similarity.

Abstract: The present invention relates to a pharmaceutical composition comprising a STT compound as an active ingredient for the prevention or treatment of Parkinson's disease. STT showed neuroprotective effect and apoptosis recovery effect in the Parkinson's disease cell model, restored the reduced motility in the MPTP animal model, and was shown to significantly protect dopamine cells, so it can be used for the prevention and treatment of Parkinson's disease.

Abstract: There are provided a method and apparatus for delivering transport characteristics of multimedia data. According to an aspect of the present invention, transport characteristics of media data that can be divided in a unit of a Media Processing Unit (MPU) are created in a unit of a predetermined number of MPUs, the created transport characteristics and a flag indicating presence or absence of the created transport characteristics are inserted into the media data, and the resultant media data is delivered. Accordingly, by using transport characteristics in units of media data unit groups, each media data unit corresponding to a short time length, it is possible to effectively control Quality of Service (QoS) in a dynamically changing transport environment, like a mobile network.

Abstract: The present invention relates to an anode active material, a nonaqueous lithium secondary battery comprising the same, and a preparation method therefor, and the purpose of the present invention is to improve high-rate charging characteristics without deterioration of charging and discharging efficiency and lifetime characteristics when applying an amorphous carbon coating layer as the anode active material of the nonaqueous lithium secondary battery, wherein the amorphous carbon coating layer comprising MoPx particles composed of MoP and MoP2 is formed on the surface of a carbon-based material, thereby reducing resistance when intercalating lithium ions into the surface of the carbon-based material, and improving reactivity and structural stability of the surface. The anode active material according to the present invention comprises a carbon-based material, and an amorphous carbon coating layer comprising MoPx particles composed of MoP and MoP2 formed on the surface of the carbon-based material.

Abstract: Disclosed are an image encoding method using a skip mode and a device using the method. The image encoding method may comprise the steps of: judging whether there is residual block data of a prediction target block on the basis of predetermined data indicating whether residual block data has been encoded; and, if there is residual block data, restoring the prediction target block on the basis of the residual block data and an intra-screen predictive value of the prediction target block. Consequently, encoding and decoding efficiency can be increased by carrying out the encoding and decoding of screen residual data only for prediction target blocks where there is a need for a residual data block in accordance with screen similarity.

Abstract: A method and apparatus use a geometric modified image for video encoding/decoding. The encoding method may include: generating a geometric modified reference picture by geometrically modifying a reference picture; generating a prediction block of a current block within an encoding target picture by performing inter prediction by referencing the reference picture or the geometrically modified reference picture; and encoding inter-prediction information of the current block.

Abstract: An artificial neural network system of the present invention can include an input layer that receives input data; an output layer that outputs output data corresponding to the input data; and a hidden layer group including a multiple number of hidden layers that are positioned between the input layer and the output layer and are connected by connection weights, with the connection weights updated based on a difference between the output data and prediction data corresponding to the input data, where each of the hidden layers can include a hidden node that includes an activation function, which can output 0 if the input value is negative and can determine the output value based on linear functions having different slopes according to the range of the input value if the input value is positive, and the linear functions can have smaller slopes for greater distances from the origin point.

Abstract: The present disclosure relates to a technical virtual sensing idea of indirectly measuring structural vibration information on an unmeasured point while minimizing the number of sensors attached for actual measurement, and more particularly, to a technique of estimating measurement data of an unmeasured point using a finite element model, synchronized and updated based on experimental data of an actual measurement subject structure, and a virtual sensing algorithm.

Abstract: An inter-prediction method according to the present invention comprises the steps of: deriving motion information of a current block; and generating a prediction block for the current block on the basis of the derived motion information. According to the present invention, computational complexity can be reduced and encoding efficiency can be improved.

Abstract: The present invention relates to a method and device for sharing a candidate list. A method of generating a merging candidate list for a predictive block may include: producing, on the basis of a coding block including a predictive block on which a parallel merging process is performed, at least one of a spatial merging candidate and a temporal merging candidate of the predictive block; and generating a single merging candidate list for the coding block on the basis of the produced merging candidate. Thus, it is possible to increase processing speeds for coding and decoding by performing inter-picture prediction in parallel on a plurality of predictive blocks.

Abstract: The invention relates to a UAV arrangement device based on machine learning for maximizing communication throughput, the UAV arrangement device including: a communication module unit that receives location information and communication demand information of a user and transmits UAV arrangement information; a user information unit that stores and analyzes the location information and the communication demand information of the user; a UAV information unit that stores basic UAV information including UAV communication throughput; and a clustering algorithm modeling unit that calculates a location at which communication throughput is maximized, with a clustering algorithm based on the location information and the communication demand information of the user.

Abstract: The present disclosure relates to a technical idea for managing radio and computing resources in coexistence edge computing. A method of allocating radio and computing resources in coexistence edge computing according to one embodiment may include a step of formulating a resource allocation problem for two different entities with conflicting relationships in minimizing latency as a generalized Nash equilibrium problem (GNEP), a step of converting the formulated GNEP into a Nash equilibrium problem (NEP), and a step of allocating resources on a penalty basis for the converted NEP.

Abstract: There is provided an image encoding/decoding method and apparatus. The image encoding method of the present invention includes: generating at least one candidate block including warped reference picture (WRP) Flag information in an advanced motion vector prediction (AMVP) mode; constructing a candidate list including the at least one candidate block; and generating a prediction block of a current block based on the candidate list.

Abstract: Disclosed herein are a method and apparatus for image encoding and decoding using prediction based on a block shape. Whether a prediction mode is available for a target block is determined. The determination is performed based on the shape of the target block. When the prediction mode is determined to be unavailable for the target block, signaling related to the prediction mode may be omitted, and determination of an additional prediction mode is performed. When the prediction mode is determined to be available for the target block, information indicating whether the prediction mode is to be used for the target block is signaled.

Abstract: The present invention discloses a thin-film light-emitting device including a charge generating junction layer and a method of fabricating the thin-film light-emitting device. The thin-film light-emitting device including a charge generating junction layer according to one embodiment of the present invention includes a negative electrode; at least one light-emitting unit formed on the negative electrode and including a charge generating junction layer, an electron injection/transport layer, a thin-film light-emitting layer, and a hole injection/transport layer in a sequential order; and a negative electrode formed on the light-emitting unit.

Abstract: The present invention relates to an apparatus for estimating the location of a receiver and a method of estimating the location of a receiver. A location estimation apparatus according to one embodiment includes a receiving device for receiving information about a plurality of beams radiated from a transmitter at different radiation angles; a radiation pattern reader for reading radiation pattern information corresponding to each of the beams based on information about the beams; and a location estimator for comparing the read radiation pattern information with each other and estimating the location of a receiver based on the comparison result.

Abstract: A super-resolution method according to the inventive concept may include receiving an input image of low resolution, separating the input image into low resolution (LR) unit patches, classifying a texture type of each of pixels included in the input image using a local binary pattern for the LR unit patches, generating high resolution (HR) unit patches corresponding to each of the pixels based on a mapping kernel corresponding to the texture type, and combining the HR unit patches based on a predetermined setting to generate an output image of high resolution.

Abstract: Disclosed is a blood-brain barrier vascular network implemented in a microfluidic chip. The blood-brain bather vascular network structure (BBB on a chip) (in vitro blood-brain bather (BBB)-on-a chip) formed in a microfluidic chip manufactured by a present manufacturing method of the in vitro blood-brain barrier (BBB)-on-a chip may reconstruct the blood-brain barrier in a real human body more similarly due to a specific cell configuration, compared to the conventional in vitro blood-brain barrier (BBB)-on-a chip, and thus may be used as a more accurate in vitro blood-brain barrier, and may be used for the development of various cellular therapeutic agents or drugs that work in the treatment of various brain diseases.