Abstract: A living organism information detection system is capable of appropriately acquiring desired information such as the existence of a living organism, the condition of the living organism, or the like by irradiating a region to be measured with an electromagnetic wave while scanning the region to be measured to thereby cause the transmission/reception of the electromagnetic wave to/from the living organism within the region to be measured to be appropriately performed to thereby accurately detect the temporal change of a phase difference signal. More specifically, an electromagnetic wave transmitting and receiving unit irradiates a region to be measured with an electromagnetic wave that is given strong directivity while scanning the region to be measured, receives a reflected wave, and acquires a phase difference signal corresponding to each position of the region to be measured, and the temporal change of the phase difference signal is detected.

Abstract: There is disclosed a bone substitute material for medical use which satisfies all the requirements of (1) no histotoxicity, (2) osteoconductivity, (3) bone replacement capability, and (4) mechanical strength necessary for a bone reconstruction operation. The bone substitute material for medical use is predominantly composed of carbonate apatite and produced through the formation of carbonate apatite by contacting a block of calcium compound with a phosphate-containing solution, wherein the calcium compound block contains substantially no powders, and at least one of said calcium compound block and said phosphate solution contains a carbonate group, without any sintering. The block of calcium compound is preferably one prepared using an artificially synthesized calcium compound, most preferably a foamed calcium compound.

Abstract: It is intended to provide a novel method of screening a drug with the use of a 67 kDa laminin receptor and a drug obtained thereby.

Abstract: A diagnosis assisting apparatus for assisting medical diagnosis that is carried out by executing a plurality of judgments relating to a medical abnormality which has appeared on an image in predetermined steps of execution, the apparatus includes a input unit configured to input a judgment result and a display unit configured to sequentially make display for prompting an input of the judgment result, based on the steps of execution and the judgment result inputted by the input unit.

Abstract: A biological evaluation method for rational and simply evaluating biological harmfulness or usefulness of a great number of natural and artificial chemicals, foods, etc. This method comprises adding a known amount of 2?-deoxyguanosine (dG) to a solution containing a test substance (drug, pesticide, functional food, etc.), optionally applying UV light and/or adding active oxygen generator, then quantifying 8-hydroxy-2?-deoxyguanosine (8OHdG) in the solution, and evaluating the toxicity or usefulness of the test substance according to the 8OhdG content (a higher 8OhdG content indicates a higher harmfulness of the test substance while a lower 8OhdG content indicates a lower harmfulness or an usefulness thereof). The invention also provide an apparatus for advantageously performing said biological evaluation method and an antioxidant preservative solution to be used in this apparatus.

Abstract: There are provided a fatigue crack growth curve estimation method, an estimation program, and an estimation device capable of strictly estimating the detail of the metal fatigue end and the crack growth detail. The fatigue crack growth curve estimation device (1) uses a first calculation means (11), second calculation means (12), third calculation means (13), fourth calculation means (14), and fifth calculation means (15) to strictly estimate the detail of growth of a crack generated and growing in a first grain while omitting a calculation on the load pair not contributing to growth of the crack.

Abstract: A method and apparatus for manufacturing a bolt capable of mass-producing a multiple screw bolt such as a so-called double screw bolt at a low unit price, and a thread rolling die for use therein. The apparatus for manufacturing a bolt comprises a pair of thread rolling dies (1) which are arranged opposite to each other at a predetermined interval, and a bolt supporting unit (2) which supports a cylindrical bolt material (3) in a predetermined position. The thread rolling dies (1) are provided with a transfer pattern (4) having a coarse thread portion (5) which is part of a coarse thread formed by developing a coarse screw, and projections (6) which are part of a fine thread (6a) formed by developing a fine screw as shown by an imaginary line (6a), the fine thread (6a) being formed cyclically on a root portion (5a) of the coarse thread according to a phase shift between the fine thread and the coarse thread.

Abstract: The present invention provides a thionucleoside-S-nitrosyl derivative of the following Formula I or a salt thereof: [wherein R1 represents ribose, 2-deoxyribose or a derivative of either, and R2 represents a hydrogen atom, an amino group, a hydroxyl group, a halogen atom, a R3-oxy group or a R3-amino group (wherein R3 represents an optionally substituted C1-15 alkyl group or an optionally substituted C1-15 acyl group)].

Abstract: It is an object of the present invention to provide an immunodeficient animal capable of generating human-derived lymphoid cells, a human-derived lymphoid cell, and a method for producing a human antigen-specific antibody. The means for solving the aforementioned object is: an immature immunodeficient mammal into which human-derived hematopoietic precursor cells have been transplanted, and which is able to generate said human-derived hematopoietic cells or immunocompetent cells; and a method for producing a human-derived antibody, which is characterized in that it comprises recovering immunocompetent cells from the above-described mammal, culturing the immunocompetent cells, and collecting a human-derived antibody from the obtained culture product.

Abstract: A biological evaluation method for rational and simply evaluating biological harmfulness or usefulness of a great number of natural and artificial chemicals, foods, etc. This method comprises adding a known amount of 2?-deoxyguanosine (dG) to a solution containing a test substance (drug, pesticide, functional food, etc.), optionally applying UV light and/or adding active oxygen generator, then quantifying 8-hydroxy-2?-deoxyguanosine (8OHdG) in the solution, and evaluating the toxicity or usefulness of the test substance according to the 8OhdG content (a higher 8OhdG content indicates a higher harmfulness of the test substance while a lower 8OhdG content indicates a lower harmfulness or an usefulness thereof) The invention also provide an apparatus for advantageously performing said biological evaluation method and an antioxidant preservative solution to be used in this apparatus.

Abstract: It is intended to provide a method of regenerating an organ or a part thereof which comprises transplanting bone marrow or hematopoietic stem cells into an injured mammal or a mammal having an injured in organ or a part thereof; a method of treating injury: a method of producing an organ or a part thereof; and an organ or a part thereof produced by this method.

Abstract: A long life fatigue strength design method for a metallic material is capable of allowing design of an optimum mechanical part according to a set service life by considering an increase in ODA (area affected by hydrogen observed blackish by a metallurgical microscope) size according to the assumed service life of the mechanical part. The method includes obtaining, from the results of a fatigue test, a functional relation between the number of stress cycles to failure and the size of a hydrogen affected area around an inclusion affected by trapped hydrogen.

Abstract: The invention provides a process for producing DNA nanocages, characterized by comprising a step of two-dimensionally assembling three types of oligonucleotides by hybridization to form tridirectionally branched double-strand DNA having self-complementary chains in the terminals, and a step of three-dimensionally self-organizing the resulting tridirectionally branched double-strand DNAs so as to consume all of the self-complementary terminals. Since the DNA nanocages according to the invention can easily be formed from DNAs by one-step procedure and include nanoparticles in the interior, the DNA nanocages are significantly effective for the development of functional materials using DNAs.

Abstract: A wind power generator provided with a wind turbine rotating in a wind tunnel body, capable of generating high output power by efficiently accelerating a wind flow. The wind power generator comprises a cylindrical wind tunnel body (1) expanding toward a flowing direction of wind and a wind turbine (3) for generating electricity disposed at a position adjacent to an inlet (2a) for wind of the wind tunnel body (1), wherein an angle of inclination &phgr; of a side wall portion of the wind tunnel body (1) against an axis of the wind tunnel body (1) is in a range from 5 to 25 degrees, the inlet (2a) of the wind tunnel body (1) has a curved surface (5) smoothly expanding toward an outside of the wind tunnel body (1), and a collar-shaped brim having a width B is formed on an outside of an opening edge of an outlet (2b) for wind of the wind tunnel body (1).