Patents Assigned to Kyushu University, National University Corporation
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Patent number: 11649387Abstract: Disclosed is a gas seal member for high-pressure hydrogen device with sufficiently reduced occurrence of both swelling destruction and blister destruction. The gas seal member is formed of a cross-linked product of an elastomer composition which comprises an elastomer and fibrous carbon nanostructures, wherein a hydrogen diffusion coefficient D1 of a cross-linked product of an elastomer component including the elastomer and a hydrogen diffusion coefficient D2 of the cross-linked product of the elastomer composition satisfy the relationship 0.7<D2/D1<1.0.Type: GrantFiled: February 13, 2018Date of Patent: May 16, 2023Assignees: KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION, ZEON CORPORATIONInventors: Shin Nishimura, Yoshihisa Takeyama
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Publication number: 20230133071Abstract: The present invention provides a GG-specific mismatch endonuclease variant, a TT-specific mismatch endonuclease variant, and a GT/TG-specific mismatch endonuclease variant. The present invention also provides a mismatch specific cleaving reaction using said variant, a method for removing errors in a nucleic acid amplification reaction using a mismatch nuclease, a method for suppressing amplification of a nucleic acid having a specific base sequence during a nucleic acid amplification reaction, and a method for detecting a nucleic acid having a single base polymorphic mutation using said suppression method.Type: ApplicationFiled: March 18, 2021Publication date: May 4, 2023Applicants: TAKARA BIO INC., EDUCATIONAL CORPORATION KANSAI BUNRI SOUGOUGAKUEN, KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATIONInventors: Hiroyuki MATSUMOTO, Takashi UEMORI, Tsuyoshi SHIRAI, Yoshizumi ISHINO, Sonoko ISHINO
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Publication number: 20230126262Abstract: The present invention relates to a method for detecting a target nucleic acid, the method including cleaving a first flap of a first cleavage structure formed by a target nucleic acid, a first nucleic acid, and a second nucleic acid; cleaving a second flap of a second cleavage structure formed by a third nucleic acid, the cleaved first flap, and a fourth nucleic acid; and detecting the presence of the target nucleic acid by detecting the cleaved second flap, wherein cleaving the first flap and cleaving the second flap are carried out by cleaving the first flap and the second flap with a flap endonuclease, and the flap endonuclease has an amino acid sequence having a sequence identity of 65% or higher with an amino acid sequence of a flap endonuclease of a microbe selected from the group consisting of microbes belonging to the Order Thermococcales and microbes belonging to the Order Methanobacteriales.Type: ApplicationFiled: February 18, 2021Publication date: April 27, 2023Applicants: TOPPAN INC., KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATIONInventors: Yoichi MAKINO, Yoshizumi ISHINO, Sonoko ISHINO
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Patent number: 11637244Abstract: A compound represented by the following general formula is excellent in light emission properties. R1 and R2 each independently represent a fluorinated alkyl group, D represents a substituent in which Hammett's ?p value is negative, and A represents a substituent in which Hammett's ?p value is positive.Type: GrantFiled: December 21, 2017Date of Patent: April 25, 2023Assignees: KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION, KYULUX, INC.Inventors: Yan Geng, Chihaya Adachi, Hajime Nakanotani, Naoto Notsuka, Keiro Nasu
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Patent number: 11627956Abstract: An automatic needle mover for moving a medical threaded needle includes: two shafts extending in the same direction and slidable relative to each other along a longitudinal direction; a needle-holding portion provided on one end side of the second shaft; a needle-receiving portion provided on one end side of the first shaft; and a handle serving as a control portion for controlling the sliding of the two shafts. The needle-holding portion has a first claw portion protruding in a direction intersecting the longitudinal direction of the shafts. The needle-receiving portion has a second claw portion protruding in a direction intersecting the longitudinal direction of the shafts. As a result of the sliding of the two shafts, the needle-holding portion and the needle-receiving portion become close to each other and a straight needle held by the needle-holding portion can be press-fitted into the needle-receiving portion.Type: GrantFiled: May 30, 2019Date of Patent: April 18, 2023Assignees: KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION, NIPPON MEDICAL SCHOOL FOUNDATIONInventors: Ryu Nakadate, Susumu Oguri, Makoto Hashizume, Akio Morita
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Publication number: 20230113730Abstract: The present invention relates to a method for detecting a target nucleic acid, the method including cleaving a first flap of a first cleavage structure formed by a target nucleic acid, a first nucleic acid, and a second nucleic acid; cleaving a second flap of a second cleavage structure formed by a third nucleic acid, the cleaved first flap, and a fourth nucleic acid; and detecting the presence of the target nucleic acid by detecting the cleaved second flap, wherein cleaving the first flap and cleaving the second flap are carried out by cleaving the first flap and the second flap with a flap endonuclease, and the flap endonuclease has an amino acid sequence having a sequence identity of 96% or higher with an amino acid sequence of a flap endonuclease of Thermococcus kodakarensis strain KOD1, or the like.Type: ApplicationFiled: February 18, 2021Publication date: April 13, 2023Applicants: TOPPAN INC., KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATIONInventors: Yoichi MAKINO, Yoshizumi ISHINO, Sonoko ISHINO
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Publication number: 20230110350Abstract: The present disclosure provides a high-pressure hydrogen apparatus gas seal member which is excellent in durability and is capable of sufficiently suppressing an occurrence of a blister fracture. A high-pressure hydrogen apparatus gas seal member of the present disclosure is a high-pressure hydrogen apparatus gas seal member made of a crosslinked product of an elastomer composition which comprises an elastomer and fibrous carbon nanostructures having an average length of 100 ?m or more and 1000 ?m or less, wherein the fibrous carbon nanostructures have a surface fractal dimension of 2.3 or more and 3.0 or less or a radius of gyration of 50 nm or more and 500 nm or less, and further the fibrous carbon nanostructures has an inner diameter of 4.0 nm or less.Type: ApplicationFiled: March 23, 2021Publication date: April 13, 2023Applicants: ZEON CORPORATION, KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATIONInventors: Yoshihisa TAKEYAMA, Shin NISHIMURA
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Patent number: 11626710Abstract: Disclosed is a current-injection organic semiconductor laser diode comprising a pair of electrodes, an optical resonator structure, and one or more organic layers including a light amplification layer composed of an organic semiconductor, which has a sufficient overlap between the distribution of excitor density and the electric field intensity distribution of the resonant optical mode during current injection to emit laser light.Type: GrantFiled: October 19, 2021Date of Patent: April 11, 2023Assignees: KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION, KOALA TECH INC.Inventors: Sangarange Don Atula Sandanayaka, Fatima Bencheikh, Kenichi Goushi, Jean-Charles Ribierre, Chihaya Adachi, Takashi Fujihara, Toshinori Matsushima
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Publication number: 20230109489Abstract: Provided is a compound that achieves a good balance between the LO. scavenging ability and the LOO. scavenging ability. The compound of the present invention or a salt thereof is represented by the following formula (1). In the formula (1), R1 and R2 may be the same or different and are each independently a hydrogen atom or an alkyl group, R3 is —OR4 or —NHR5, R4 is a sec-butyl group, a tert-butyl group, or an iso-butyl group, and R5 is a sec-butyl group, a tert-butyl group, or an iso-butyl group.Type: ApplicationFiled: February 12, 2021Publication date: April 6, 2023Applicants: FELIQS CORPORATION, KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATIONInventors: Kenichi Yamada, Kenichiro Kuninobu
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Patent number: 11618958Abstract: A hydrogen-oxygen generation system includes an electrolytic cell configured to generate hydrogen and oxygen by electrolyzing water, and discharge the hydrogen and the oxygen as separate generated gasses. An accumulator includes a water storage chamber configured to store the water, and a gas chamber configured to receive a pressurized gas, and the water storage chamber and the gas chamber are separated from each other by an elastic body membrane. The accumulator is configured to transfer the water stored in the water storage chamber toward the electrolytic cell at a transfer pressure in accordance with a pressure of the pressurized gas in the gas chamber. A water supply unit is configured to supply the water to the water storage chamber, and a gas supply unit is configured to supply the pressurized gas to the gas chamber.Type: GrantFiled: October 24, 2019Date of Patent: April 4, 2023Assignees: MITSUBISHI HEAVY INDUSTRIES, LTD., JAPAN AEROSPACE EXPLORATION AGENCY, KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATIONInventors: Atsuko Homma, Kenichi Nagamoto, Naoki Ogawa, Yuta Nakatsuchi, Hidehiko Tajima, Yusaku Nasu, Yoshitsugu Sone, Hiroshige Matsumoto
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Publication number: 20230092815Abstract: The present disclosure is intended to enhance various effects of a green tea extract such as catechin in the most effective manner. The ratio (B/A) of epigallocatechin gallate (A) contained in the green tea extract and flavanone glycoside (B) contained in the citrus extract is 0.2<B/A<1.6, or a ratio (C/A) of epigallocatechin gallate (A) and eriocitrin (C) contained in the citrus extract is 0.2<C/A<0.5.Type: ApplicationFiled: March 3, 2021Publication date: March 23, 2023Applicants: Toyota Jidosha Kabushiki Kaisha, Kyushu University, National University CorporationInventors: Akari Nakasone, Madoka Abe, Hirofumi Tachibana
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Publication number: 20230085804Abstract: A fold line design method is a method for folding a target member. The method includes: setting a ribbase on a plane along a main surface of the target member; designing a plurality of first fold lines each of which extend radially from the ribbase as a starting point, and in which a mountain fold line and a valley fold line are alternately disposed; and designing a plurality of second fold lines which respectively connect the first fold lines adjacent to each other among the plurality of first fold lines, and constitute one continuous fold line.Type: ApplicationFiled: November 22, 2022Publication date: March 23, 2023Applicant: KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATIONInventor: Kazuya SAITO
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Patent number: 11603337Abstract: Provided is a method for producing an optically active substance, the method including an asymmetric induction, wherein an asymmetry inducer is allowed to act on a chiral molecule having a half-life of enantiomeric excess of shorter than 10 hours, thereby increasing abundance of one enantiomer of the chiral molecule. According to this method, one enantiomer of a chiral molecule that is susceptible to racemization can be selectively and efficiently obtained.Type: GrantFiled: May 16, 2018Date of Patent: March 14, 2023Assignees: DAICEL CORPORATION, KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATIONInventors: Katsuhiko Tomooka, Kazunobu Igawa
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Publication number: 20230047707Abstract: A thermally conductive filler capable of exhibiting high thermal conductive properties with its specific gravity being reduced, a thermally conductive composite material and a wire harness that contains such a thermally conductive filler, and a method for forming a thermally conductive filler that can be used to form such a thermally conductive filler. A thermally conductive filler includes a hollow particle having a polar group on its surface, and a thermally conductive layer containing an inorganic compound that covers the surface of the hollow particle. Also, a thermally conductive composite material contains the thermally conductive filler and a matrix material, the thermally conductive filler being dispersed in the matrix material. Furthermore, a wire harness contains the thermally conductive composite material.Type: ApplicationFiled: December 4, 2020Publication date: February 16, 2023Applicants: AUTONETWORKS TECHNOLOGIES, LTD., SUMITOMO WIRING SYSTEMS, LTD., SUMITOMO ELECTRIC INDUSTRIES, LTD., KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATIONInventors: Naoyuki OSHIUMI, Takehiro HOSOKAWA, Kazuo NAKASHIMA, Takashi KAWAKAMI, Yusaku MAEDA, Makoto MIZOGUCHI
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Publication number: 20230053098Abstract: Provided is an organic light-emitting element that is excited by an electromagnetic wave. The organic light-emitting element includes: a first electrode; a second electrode disposed to face the first electrode; an organic light-emitting layer disposed between the first electrode and the second electrode, where separation of charges occurs due to incidence of the electromagnetic wave; a hole transporting layer disposed between the first electrode and the organic light-emitting layer; and a charge block layer disposed between the second electrode and the organic light-emitting layer. The charge block layer has a LUMO level shallower than a LUMO level of organic light emitters included in the organic light-emitting layer.Type: ApplicationFiled: August 9, 2022Publication date: February 16, 2023Applicants: HAMAMATSU PHOTONICS K.K., KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATIONInventors: Takahiko YAMANAKA, Shigeo HARA, Chihaya ADACHI, Hajime NAKANOTANI
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Publication number: 20230049879Abstract: There are provided an aqueous electrolyte solution having an extended potential window, in particular, an aqueous electrolyte solution whose potential window is further wider than those exhibited by conventional concentrated aqueous electrolyte solutions, and an aqueous electrolyte solution in which the cycle characteristics can be improved. A non-aqueous electrolyte solution capable of achieving a higher energy density is provided, the non-aqueous electrolyte solution containing easily available and inexpensive materials and having further improved characteristics. One aqueous electrolyte solution of the present embodiment contains a salt of at least one selected from the group consisting of sodium, magnesium, potassium and lithium, and a chaotropic additive. One other non-aqueous electrolyte solution of the present embodiment contains a salt of at least one selected from the group consisting of sodium, magnesium, potassium and lithium, and a chaotropic additive.Type: ApplicationFiled: November 2, 2020Publication date: February 16, 2023Applicants: KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION, TOSOH CORPORATIONInventors: Shigeto OKADA, Ryo SAKAMOTO, Masato ITO, Kotaro USHIJIMA, Toshiya TAKAHARA, Wataru KOBAYASHI, Masaki OKADA
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Publication number: 20230030314Abstract: The present invention discloses a method for diagnosing cancer comprising a step of detecting active protein kinase C? in urine.Type: ApplicationFiled: December 4, 2020Publication date: February 2, 2023Applicant: Kyushu University, National University CorporationInventors: Masaharu Murata, Takahito Kawano, Masatoshi Eto, Junichi Inokuchi, Jeong-Hun Kang
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Publication number: 20230027404Abstract: The present invention provides a microstructure in which evenly distributed crystal grains line up in parallel lines extending along the surface of the film, and a no-lateral-growth region left at each of locations exposed to both ends of a grain interface, which serves as a partition between the neighboring two crystal grains. According to the present invention, there are also provided: a method for forming a polycrystalline film, such as a thin polycrystalline silicon film, a thin aluminum film, and a thin copper film, which is flat and even, in surface, electrically uniform and stable, and mechanically stable; a laser crystallization device for use in manufacture of polycrystalline films, and a semiconductor device using the polycrystalline film and having good electrical property and increased breakdown voltage.Type: ApplicationFiled: December 15, 2020Publication date: January 26, 2023Applicants: V TECHNOLOGY CO., LTD., KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATIONInventors: Jun GOTOH, Kaori SAITO, Hiroshi IKENOUE
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Publication number: 20230002650Abstract: The present invention is to provide an adhesive composition which comprises a copolymer A which contains a recurring unit having a cyclic ether structure and a recurring unit having a benzophenone structure, and a copolymer B which contains a recurring unit having a betaine structure and a recurring unit having a hydroxyl group, a cured product thereof, and a method for producing the cured product. The adhesive composition of the present invention is capable of curing in water, has high hydrophilicity, and is capable of forming a cured product having an excellent ability to inhibit adhesion of biological substances.Type: ApplicationFiled: August 25, 2020Publication date: January 5, 2023Applicants: KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION, NISSAN CHEMICAL CORPORATIONInventors: Masayasu TOTANI, Keiji TANAKA, Hisao MATSUNO, Masaaki OZAWA, Junko KATAYAMA
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Patent number: 11545631Abstract: An organic electroluminescence device in which a polycyclic compound including an electron donor and an electron acceptor is included in an emission layer is provided. The electron donor contains an acridine derivative or a dibenzo-azasiline derivative, and the electron acceptor contains B as a ring-forming atom, O or S directly bonded to B, and a heterocyclic group in which three or five hexagonal rings are condensed. Accordingly, an organic electroluminescence device having high efficiency may be achieved.Type: GrantFiled: October 9, 2019Date of Patent: January 3, 2023Assignees: Samsung Display Co., Ltd., Kyushu University, National University CorporationInventors: Yuuki Miyazaki, Yoshimasa Fujita, Kyohei Matsuo, Takuma Yasuda