Abstract: Provided herein are methods of increasing T-cell function and T-cells produced by these methods. Also provided herein are methods of treating a subject using T-cells produced by these methods.
Type:
Application
Filed:
January 19, 2024
Publication date:
May 16, 2024
Applicant:
Kyverna Therapeutics, Inc.
Inventors:
John Lee, Erin O’Brien, Jordan Tsai, Lih-Yun Hsu, Faye Wu
Abstract: Provided herein are methods of increasing T-cell function and T-cells produced by these methods. Also provided herein are methods of treating a subject using T-cells produced by these methods.
Type:
Grant
Filed:
October 21, 2022
Date of Patent:
January 23, 2024
Assignee:
Kyverna Therapeutics, Inc.
Inventors:
John Lee, Erin O'Brien, Jordan Tsai, Lih-Yun Hsu, Faye Wu
Abstract: This document relates to methods and materials for treating a mammal having an autoimmune disease. For example, materials and methods for producing a T cell comprising a FOXP3 polypeptide. Methods and materials for treating a mammal having an autoimmune disease comprising administering to a mammal having an autoimmune disease an effective amount of a T cell are also provided herein.
Type:
Application
Filed:
November 11, 2022
Publication date:
October 19, 2023
Applicant:
Kyverna Therapeutics, Inc.
Inventors:
Mamle Quarmyne, Faye Wu, Jordan Tsai, John Lee, Jeffrey Greve, Joseph Cheng, Meghana Vijayraghavan
Abstract: Provided herein are methods of increasing T-cell function and T-cells produced by these methods. Also provided herein are methods of treating a subject using T-cells produced by these methods.
Type:
Application
Filed:
October 21, 2022
Publication date:
June 8, 2023
Applicant:
Kyverna Therapeutics, Inc.
Inventors:
John Lee, Erin O'Brien, Jordan Tsai, Lih-Yun Hsu, Faye Wu
Abstract: This document relates to methods and materials for treating a mammal having an autoimmune disease. For example, materials and methods for producing a T cell comprising a FOXP3 polypeptide and one or more transcription factors are provided herein. Methods and materials for treating a mammal having an autoimmune disease comprising administering to a mammal having an autoimmune disease an effective amount of a T cell are also provided herein.
Type:
Application
Filed:
November 2, 2022
Publication date:
April 6, 2023
Applicant:
Kyverna Therapeutics, Inc.
Inventors:
Ashley Mahne, John Lee, Lih-Yun Hsu, Jeffrey Greve
Abstract: This document relates to methods and materials for treating a mammal having an autoimmune disease. For example, materials and methods for producing a T cell comprising a FOXP3 polypeptide and one or more transcription factors are provided herein. Methods and materials for treating a mammal having an autoimmune disease comprising administering to a mammal having an autoimmune disease an effective amount of a T cell are also provided herein.
Type:
Grant
Filed:
December 16, 2021
Date of Patent:
September 20, 2022
Assignee:
Kyverna Therapeutics, Inc.
Inventors:
Ashley Mahne, John Lee, Lih-Yun Hsu, Jeffrey Greve