Patents Assigned to L'Assistance Publique--Hospitaux de Paris
  • Method for the diagnosis of CADASIL
    Patent number: 5616462
    Abstract: Genotypic diagnosis of CADASIL for symptomatic or at risk individuals or fetuses belonging to a family suspected of being affected by CADASIL is carried out by detecting DNA polymorphisms genetically linked to the mutated gene responsible for CADASIL, these DNA polymorphisms being located in the genetic interval of the chromosome 19 flanked by the microsatellites D198221 and D19S215 and including these microsatellites.
    Type: Grant
    Filed: February 28, 1994
    Date of Patent: April 1, 1997
    Assignee: L'Assistance Publique--Hospitaux de Paris
    Inventors: Anne M. G. Joutel, Marie-Germaine M. Bousser, Elisabeth A. Tournier-Lasserve