Abstract: The present invention concerns a method for cleaning a reactor (4) for treating a lignocellulosic biomass (P), said method comprising the following steps: a) draining the reactor of the reaction mixture containing the biomass, b) filling the reactor with a basic aqueous solution (EB), c) draining the reactor, d) injecting steam (V) into the reactor, e) filling the reactor with an aqueous solution (E), f) draining the reactor.

Abstract: The present invention relates to compositions and methods for detecting muscle atrophy in a subject. The invention also provides novel biomarkers that allow in vitro or ex vivo detection of a loss of muscle mass in a subject. The invention also relates to the use of muscle atrophy as an indicator of the occurrence, or the risk of occurrence of a disease or a disorder in a subject. Furthermore, the invention relates to a kits and reagents for use in these methods.

Abstract: Disclosed is a microorganism, which has been engineered to acquire methylotrophy. More particularly, the application describes a non-naturally occurring microorganism, which has been engineered to express or include a first enzyme and a second enzyme, wherein the first enzyme is a methanol dehydrogenase (Mdh) enzyme or a methanol oxidase (Mox) enzyme, and wherein the second enzyme is a dihydroxyacetone synthase (Das) enzyme or a transketolase enzyme. The application also describes element and applications, more particularly kits and methods, which include or use the microorganism.

Abstract: A process for preparing a powder of a material of natural origin, which includes a step of treating a substance containing at least 70% by weight of one or more leather wastes in particle form in a twin-screw extruder, wherein a temperature profile is applied that increases from an initial temperature of between 10 and 40° C. up to a maximum temperature of between 60 and 120° C., in the presence of water in an amount such that the weight ratio of water to substance is between 0.20 and 6.

Abstract: A composition including an extract of Moricandia for the use thereof in the prevention and/or treatment of metabolic diseases related to impaired glucose tolerance and/or insulin resistance. Also a composition including an extract of Moricandia for the use thereof in the prevention of weight gain, in particular of body fat.

Abstract: Process for producing biogas from a digestate obtained from a digester, said process comprising a step of recovering the digestate at the outlet of a digester, a post-digester or a storage tank; a step of separating the digestate into a solid digestate and a liquid digestate; a step of introducing the solid digestate into at least one dosed tank; a step of anaerobic digestion in the tank with neither heating nor mixing; and a step of recovering the biogas at the tank outlet.

Abstract: Various components for artificial candles and other lighting devices are described that can be used to create a realistic flame effect in the devices. The devices include a flame piece or element that extends upwardly from a body of the device. A light source can be disposed with respect to the flame piece such that the flame piece is illuminated. A variety of drive mechanisms could be disposed within the body of the device that can cause movement of the flame piece with respect to the body or housing. The flame piece can be coupled to a body or housing of the device using various components to suspend at least a portion of the flame piece within the body or housing.

Abstract: Methods, systems, and devices relating to an electronic scented candle that is convenient to use and enables rapid generation and dissipation of scented materials are described. One electronic candle device includes a shell that has a through hole, a flame element protruding through the through hole, an installation lid including a locking base to allow removable coupling of a fragrance container, a scent chamber including a locking clip, a first channel, a second channel, a third channel, and a fourth channel. The scent chamber is removably coupled to the locking base by the locking clip, and an air pump provided to supply pressurized air.

Abstract: A composition including an extract of Moricandia for the use thereof in the prevention and/or treatment of metabolic diseases related to impaired glucose tolerance and/or insulin resistance. Also a composition including an extract of Moricandia for the use thereof in the prevention of weight gain, in particular of body fat.

Abstract: The present invention relates to methods for predicting the risk of developing pulmonary colonization/infection by P. aeruginosa. The inventors analyzed the respiratory tract microbiota from 65 patients sputum samples and compared microbiota data. The inventors found that patients that will remain uninfected from P. aeruginosa exhibited 3-fold higher abundance of Porphyromonas catoniae compared to the other groups. In particular, the present invention relates to a method for predicting the risk of developing pulmonary colonization/infection by P. aeruginosa in a subject suffering from cystic fibrosis (CF) comprising measuring the abundance of Porphyromonas catoniae in a biological sample obtained from said subject.

Abstract: Methods, systems and devices associated with an electronic candle are described. In one example, an electronic candle comprises a housing having a through-hole at its top and a component shell. The component shell encloses a transfer mechanism including a driver motor and one or more gears positioned inside the component shell, a light emitting component coupled to the transfer mechanism such that the transfer mechanism causes the light emitting component to move vertically up or down to protrude from the housing or to retract into the housing, a lid positioned inside the component shell and movable to remain in at least one of an open configuration or a closed configuration, and a controller configured to turn on or off the light emitting component. The candle also includes a controller configured to turn on or off the light emitting component.

Abstract: The present invention relates to the allergy field. Several independent groups have recently investigated the implication of PCSK9 on inflammation and sepsis but none of them have determined its impact on allergies and/or asthma which is a global health burden. Inventors have obtained preliminary data on wild-type (PCSK9+/+) or PCSK9-deficient mice (PCSK9?/?) and shown that, under basal condition and in the absence of a particular stimulus, PCSK9 deficiency significantly increases the percentage of regulatory T cells in the spleen, the mesenteric lymph nodes and Peyer's patches. Moreover, inventors have shown the effect of allergic challenge on primary human bronchial epithelial cells on PCSK9 expression and secretion. Very interestingly, their first results obtained by Q-PCR showed that HDM and LPS increase PCSK9 mRNA levels. Accordingly, the present invention relates to inhibitors of PCSK9 for use in the treatment of asthma and/or allergic disease, such as food allergy.

Abstract: A pendant lighting fixture can include an outer casing, a hollow body positioned within the outer casing, a motion generator positioned within the hollow body, and an illumination assembly within a chamber formed by a cover. An upper part of the hollow body is configured to be coupled to a hanging mechanism, and a lower part of the hollow body is removably coupled to the cover. The motion generator comprises a container, a magnetic coil configured to generate a magnetic field, and an object movably responsive to the magnetic field move within the container so that a movement of the object of the motion generator by the magnetic field affects an illumination effect of the illumination assembly.

Abstract: A meat analogue may include a macrostructure of connected sheared fibers oriented parallel to one another and gaps positioned between the sheared fibers. The macrostructure may not include meat and may include a vegetable protein. An extrusion system may include an extruder and a die. The extrusion system may produce a meat analogue. A meat analogue may include a plant protein. The extruder may be connectable to the die. The extrusion system may be configured to direct a material including a vegetable protein from the extruder to the die and through a fluid path extending through the die. The die may be configured to inject a fat or a fat analogue into the material such that the fat or the fat analogue is embedded but visually distinct from the material including the vegetable protein when the fat or the fat analogue and the material exit the die.

Abstract: An adhesive composition including a calcium phosphate ceramic selected from tetracalcium phosphate and alpha-tricalcium phosphate, phosphorylated serine, polydopamine, and an aqueous solvent. Also, a kit for preparing the adhesive composition, which includes the calcium phosphate ceramic, phosphorylated serine, and polydopamine and a method for preparing the adhesive composition, as well as the uses thereof.

Abstract: The invention is related to an inducible promoter for improved and regulated gene expression, useful in synthetic biology and metabolic engineering. In particular, the present invention relates to a nucleotide sequence comprising the regulatory regions of an erythritol- and erythrulose-inducible promoter in yeast and uses thereof in an expression system thus allowing an improved and regulated gene expression and production of gene product.

Abstract: The invention relates to a Coanda effect flow booster (10) for inducing a boosted flow of gas, comprising: —a main air circulation pipeline (14), —at least one injection opening that opens into the main pipeline (14), —a plurality of openings for supplying compressed motive gas, each opening configured to be connected to a source of compressed motive gas in order to supply the at least one injection opening with compressed motive gas, —at least one distribution pipeline connecting the plurality of supply openings to the at least one injection opening, —a booster profile (48) at least partially defining the at least one injection opening and forming a convex surface configured to create a Coanda effect in a flow of compressed motive gas injected through the at least one injection opening.

Abstract: Methods, systems and devices associated with an electronic candle are disclosed. In one example aspect, an electronic candle includes a mounting frame that includes a first connector and a power supply assembly that is detachable from the mounting frame. The power supply assembly includes a second connector that forms a coupling mechanism with the first connector. The power supply assembly further includes an energy storage, a first power source configured to charge the energy storage, and an electrical connection interface configured to connect the power supply assembly to a second power source. The electronic candle also includes a light-emitting assembly that is removably coupled to the mounting frame configured to operate using power provided by the power supply assembly, and one or more controllers configured to control an operation of the light-emitting assembly.

Abstract: A fusion protein including fragments of the spike protein and of the nucleoprotein of a coronavirus. Also a vaccine, a composition, a pharmaceutical composition, or a diagnostic kit including the fusion protein, a method for diagnosing an infection by a coronavirus and to a method for preventing or treating a coronavirus infection based on the use of the fusion protein.

Abstract: An optimised bio-electrochemical reactor for treating a liquid effluent containing a biodegradable organic pollution. At least one of the anode and cathode compartments of the reactor is a microbial biofilm compartment (12) including a multi-stage current collector immersed in an electrolyte comprising electroactive microorganisms. This current collector includes at least two stages, each defining a chamber acting as a container for a biocompatible granular support material and letting the fluid pass through. The effluent circulates inside the compartment (12) according to an X direction crossing the stages of the current collector. In operation, the support material (17) is in a fluidised state resulting either from the circulation of the effluent, or from the circulation of a fluidisation gas allowing optimising the active surface of the electrode and, consequently, the treatment of the effluent.