Patents Assigned to L. Molteni & C. Dei Fratelli
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Patent number: 10922382Abstract: There is described a precision dispenser for liquids, in particular medications, which allows the remote control of all operations associated with dispensing the medication to the patient so as to avoid abuses.Type: GrantFiled: March 1, 2017Date of Patent: February 16, 2021Assignee: L. MOLTENI & C. DEI FRATELLI ALITTI—SOCIETE DI ESERCIZIO S.P.A.Inventor: Roberto Angeli
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Publication number: 20130059876Abstract: Liquid formulations for administration of naltrexone at low concentrations by the nasal route are described.Type: ApplicationFiled: May 20, 2011Publication date: March 7, 2013Applicant: L Molteni & C Dei Fratelli Alitti Societa Di Esercizio S.p.AInventors: Roberto Angeli, William Raffaeli, Maria Adele Rigamonti
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Publication number: 20130011479Abstract: Immediate-release formulations are described, consisting of double-layer tablets wherein one layers contains an opioid agonist and the other an opioid antagonist.Type: ApplicationFiled: March 23, 2011Publication date: January 10, 2013Applicant: L. MOLTENI & C. DEI FRATELLI ALITTI SOCIETA' DI ESERCIZIO S.p.AInventors: Roberto Angeli, William Raffaeli, Maria Adele Rigamonti
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Patent number: 8288528Abstract: Meso-substituted porphyrins of general formula (I) suitable for the use as photosensitizing agents, in particular in photodynamic therapy, are herein described.Type: GrantFiled: January 14, 2011Date of Patent: October 16, 2012Assignee: L. Molteni & C. Dei Fratelli Alitti—Società di Esercizio S.p.A.Inventors: Gabrio Roncucci, Donata Dei, Francesca Giuntini, Giacomo Chiti, Daniele Nistri, Lia Fantetti, Valentina Paschetta, Annalisa Cocchi
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Patent number: 8242262Abstract: A process is described for preparing chlorides of phthalocyanine derivatives comprising at least a quaternary ammonium group, products useful as photosensitizing agents in photodynamic therapy.Type: GrantFiled: May 4, 2006Date of Patent: August 14, 2012Assignee: L. Molteni & C. Dei Fratelli Alitti Societa'di Esercizio S.p.A.Inventors: Donata Dei, Giacomo Chiti, Daniele Nistri, Gabrio Roncucci, Aldo Hendrikus Velders, Salvatore Demartis, Valentina Paschetta
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Patent number: 8067404Abstract: Phthalocyanine derivatives are described having photosensitizing characteristics and high solubility in water, useful for photodynamic treatment of bacterial infections, in particular infections generated by Gram-negative bacteria.Type: GrantFiled: May 4, 2006Date of Patent: November 29, 2011Assignee: L. Molteni & C. Dei Fratelli Alitti Societa'di Esercizio S.p.A.Inventors: Gabrio Roncucci, Giacomo Chiti, Donata Dei, Annalisa Cocchi, Lia Fantetti, Stefano Mascheroni
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Patent number: 7947674Abstract: Meso-substituted porphyrins of general formula (I) suitable for the use as photosensitizing agents, in particular in photodynamic therapy, are herein described.Type: GrantFiled: October 21, 2003Date of Patent: May 24, 2011Assignee: L. Molteni & C. Dei Fratelli AlittiInventors: Gabrio Roncucci, Donata Dei, Francesca Giuntini, Giacomo Chiti, Daniele Nistri, Lia Fantetti, Valentina Paschetta, Annalisa Cocchi
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Publication number: 20110112464Abstract: Meso-substituted porphyrins of general formula (I) suitable for the use as photosensitising agents, in particular in photodynamic therapy, are herein described.Type: ApplicationFiled: January 14, 2011Publication date: May 12, 2011Applicant: L. Molteni & C. Dei Fratelli Alitti Societa Di Esercizio S.P.A.Inventors: Gabrio Roncucci, Donata Dei, Francesca Giuntini, Giacomo Chiti, Daniele Nistri, Lia Fantetti, Valentina Paschetta, Annalisa Cocchi
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Patent number: 7915248Abstract: The present invention relates to metal-phthalocyanines bearing at least a group containing boron isotopes 11B or 10B, covalently bound to the axial positions of metal-phthalocyanine nucleus; moreover it refers to the process for their preparation, the pharmaceutical compositions comprising them and their use for the treatment of neoplastic and dysplastic pathologies in PDT and/or BNCT.Type: GrantFiled: September 10, 2005Date of Patent: March 29, 2011Assignee: L. Molteni & C. Dei Fratelli Alitti Societa'Di Esercizio S.p.AInventors: Donata Dei, Gabrio Roncucci, Daniele Nistri, Yann Raoul, Giacomo Chiti, Moira Municchi, Giulio Jori
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Patent number: 7842682Abstract: The present invention relates to meta 1-phthalocyanines bearing at least a group containing boron isotopes 11B or 10B, covalently bound to the peripheral positions of meta 1-phthalocyanine nucleus; moreover it refers to the processes for their preparation, the pharmaceutical compositions comprising them and their use for the treatment of neoplastic and dysplastic pathologies.Type: GrantFiled: March 11, 2004Date of Patent: November 30, 2010Assignee: L. Molteni & C. Dei Fratelli AlittiInventors: Gabrio Roncucci, Giulio Jori, Francesca Giuntini, Clara Fabris, Giacomo Chiti, Moira Municchi, Donata Dei
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Patent number: 7749991Abstract: The present invention is directed to metal-phthalocyanines of general formula (I) to the corresponding conjugates, the processes for their preparation and use in the photodynamic therapy of microbial infections (viral, bacterial and mycotic), tumor, pre-cancerous and proliferative pathologies and/or in the diagnosis, as well as for blood and blood derivatives sterilization.Type: GrantFiled: November 16, 2006Date of Patent: July 6, 2010Assignee: L. Molteni & C. Dei Fratelli Alitti-Societa di Esercizio S.p.A.Inventors: Gabrio Roncucci, Lia Fantetti, Maria Paola De Filippis, Donata Dei, Giulio Jori
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Publication number: 20090130049Abstract: Self-sterilising products, and in particular novel products comprising phthalocyanine derivatives bound to polymers, a process for the preparation of said products and their use for preparing self-sterilising industrial and medical articles or devices, are described.Type: ApplicationFiled: June 29, 2006Publication date: May 21, 2009Applicant: L. Molteni & C. Dei Fratelli Alitti Societa' Di Esercizio S.P.A.Inventors: Gabrio Roncucci, Lia Fantetti, Giacomo Chiti, Donata Dei, Carmela Alongi, Annalisa Cocchi, Valentina Paschetta
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Publication number: 20090131392Abstract: Phthalocyanine derivatives are described having photosensitising characteristics and high solubility in water, useful for photodynamic treatment of bacterial infections, in particular infections generated by Gram-negative bacteria.Type: ApplicationFiled: May 4, 2006Publication date: May 21, 2009Applicant: L. MOLTENI & C. DEI FRATELLI ALITTI SOCIETA' DI ESERCIZIO S.P.A.Inventors: Gabrio Roncucci, Giacomo Chiti, Donata Dei, Annalisa Cocchi, Lia Fantetti, Stefano Mascheroni
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Publication number: 20090131393Abstract: A process is described for preparing chlorides of phthalocyanine derivatives comprising at least a quaternary ammonium group, products useful as photosensitising agents in photodynamic therapy.Type: ApplicationFiled: May 4, 2006Publication date: May 21, 2009Applicant: L. Molteni & C. Dei Fratelli Alitti Societa' Di Esercizio S.P.A.Inventors: Donata Dei, Giacomo Chiti, Daniele Nistri, Gabrio Roncucci, Aldo Hendrikus Velders, Salvatore Demartis, Valentina Paschetta
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Publication number: 20080009464Abstract: The present invention relates to meta 1-phthalocyanines bearing at least a group containing boron isotopes 11B or 10B, covalently bound to the peripheral positions of meta 1-phthalocyanine nucleus; moreover it refers to the processes for their preparation, the pharmaceutical compositions comprising them and their use for the treatment of neoplastic and dysplastic pathologies.Type: ApplicationFiled: March 11, 2004Publication date: January 10, 2008Applicant: L. Molteni & C. dei Fratelli Alitti Societa di Esercizio S.p.A.Inventors: Gabrio Roncucci, Giulio Jori, Francesca Giuntini, Clara Fabris, Giacomo Chiti, Moira Municchi, Donata Dei
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Patent number: 7265100Abstract: The present invention refers to a process for the separation of regioisomeric mixtures of metal phthalocyanines of formula (I), to the regioisomers obtained by this process, and their use as phototherapeutic and photodiagnostic agentsType: GrantFiled: October 28, 2002Date of Patent: September 4, 2007Assignee: L. Molteni & C. Dei Fratelli Alitti Societa' di Esercizio S.p.A.Inventors: Gabrio Roncucci, Francesca Giuntini, Donata Dei, Maria Paola De Filippis, Paolo Sarri, Marco Possenti, Valentina Paschetta, Giacomo Chiti
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Patent number: 7153841Abstract: Phthalocyanine analogues having an active group able to link the phthalocyanine t carriers molecules and phthalocyanine to carriers molecules and phthalocyanine analogues as phthalocyanine-carrier conjugates showing enhanced photodynamic properties, red shifted absorption characteristic, all useful for photodynamic therapy, are described. Photosensitizers themselves or the photosensitizers-carriers conjugates are useful compounds either for treatment of various infectious diseases, the in vivo eradication of micro-organisms as well as diseases characterized by cellular hyperproliferation, in particular tumours psoriasis, actinic keratosis, atheromas, endoarterial hyperplasia and prostate hyperplasia. The above compounds can be also useful for blood and blood derivatives sterilization and in vivo/vitro diagnostics.Type: GrantFiled: March 20, 2002Date of Patent: December 26, 2006Assignee: L. Molteni & C. Dei Fratelli Alitti Societa Di Esercizio S.p.A.Inventors: Gabrio Roncucci, Donata Dei, Maria Paola De Filippis, Lia Fantetti, Daniele Nistri
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Patent number: 7144879Abstract: The present invention is directed to metal-phthalocyanines of general formula (I) to the corresponding conjugates, the processes for their preparation and use in the photodynamic therapy of microbial infections (viral, bacterial and mycotic), tumor, pre-cancerous and proliferative pathologies and/or in the diagnosis, as well as for blood and blood derivatives sterilizationType: GrantFiled: June 11, 2001Date of Patent: December 5, 2006Assignee: L. Molteni & C. Dei FratelliInventors: Gabrio Roncucci, Lia Fantetti, Maria Paola De Filippis, Donata Dei, Giulio Jori
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Publication number: 20060135478Abstract: The present invention relates to meta 1-phthalocyanines bearing at least a group containing boron isotopes 11B or 10B, covalently bound to the peripheral positions of meta 1-phthalocyanine nucleus; moreover it refers to the processes for their preparation, the pharmaceutical compositions comprising them and their use for the treatment of neoplastic and dysplastic pathologies.Type: ApplicationFiled: March 11, 2004Publication date: June 22, 2006Applicant: L. Molteni & C. dei Fratelli Alitti Societa di Esercizio S.p.A.Inventors: Gabrio Roncucci, Giulio Jori, Francesca Giuntini, Clara Fabris, Giacomo Chiti, Moira Municchi, Donata Dei
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Publication number: 20060040914Abstract: Meso-substituted porphyrins of general formula (I) suitable for the use as photosensitising agents, in particular in photodynamnic therapy, are herein described.Type: ApplicationFiled: October 21, 2003Publication date: February 23, 2006Applicant: L. MOLTENI & C. DEI FRATELLI ALITTI SOCIETA DI ESERCIZIO S.P.A.Inventors: Gabrio Roncucci, Donata Dei, Francesca Giuntini, Giacomo Chiti, Daniele Nistri, Lia Fantetti, Valentina Paschetta, Annalisa Cocchi