Abstract: The present invention relates to compositions comprising an agent, like a polynucleotide, which induces or upregulates expression of UCP1 for use in treating or preventing a disorder of the energy homeostasis, overweight, adiposity, obesity, metabolic syndrome or related diseases or disorders in a subject. The present invention also relates to a method of treating or preventing a disorder of the energy homeostasis, overweight, adiposity, obesity, metabolic syndrome or related diseases or disorders in a subject comprising administrating a composition comprising a polynucleotide which induces or upregulates expression of UCP1.
Type:
Application
Filed:
March 22, 2016
Publication date:
October 13, 2016
Applicants:
Centre National de la Recherche Scientifique, l'Université Nice Sophia Antipolis
Inventors:
Marcel SCHEIDELER, Michael KARBIENER, Ez-Zoubir AMRI, Gérard AILHAUD, Christian DANI
Abstract: The present invention relates to compositions comprising an agent, like a polynucleotide, which induces or upregulates expression of UCP1 for use in treating or preventing a disorder of the energy homeostasis, overweight, adiposity, obesity, metabolic syndrome or related diseases or disorders in a subject. The present invention also relates to a method of treating or preventing a disorder of the energy homeostasis, overweight, adiposity, obesity, metabolic syndrome or related diseases or disorders in a subject comprising administrating a composition comprising a polynucleotide which induces or upregulates expression of UCP1.
Type:
Grant
Filed:
May 6, 2011
Date of Patent:
April 26, 2016
Assignees:
Centre National de la Recherche Scientifique, l'Université Nice Sophia Antipolis
Inventors:
Marcel Scheideler, Michael Karbiener, Ez-Zoubir Amri, Gérard Ailhaud, Christian Dani