Abstract: The present invention provides an insoluble enzymatic reagent for detecting products derived from glucuronide metabolites in a sample, containing an enzyme with glucuronidase activity immobilized on a resin comprising a polysaccharide modified with chemical groups, and optionally a cationic polymer. Additionally, it provides methods for preparing said enzymatic reagent and for detecting derivatives of glucuronide metabolites in a sample, using said reagent.
Type:
Grant
Filed:
July 13, 2017
Date of Patent:
December 17, 2019
Assignee:
LA PIEDRA BIOTECNOLOGÍA SPA
Inventors:
Manuel Rozas Andreu, Fernando Alexis Gutierrez Rojas, Rocio Andrea Peralta Villalobos