Abstract: A self-serve kiosk includes a blood, fluid or tissue test device for obtaining a blood, fluid or tissue sample from a user, analyzing the sample, and generating in vitro diagnostic data. The kiosk may also have non-invasive test devices for obtaining vitals measurements from the user, such as a weight scale, a blood pressure device and a heart rate monitor. A user interface such as a touch screen obtains input of personal health information from the user. The test measurements and input data are analyzed, and a health snapshot, risk assessment, guidance plans and incentives are generated and provided to the user.