Abstract: A method of detecting the presence of bioactive molecules in a fluid sample, comprising contacting a solution of a microorganism selected from the group consisting of a monocellular algae and a cyanobacteria with the fluid sample so as to obtain a formulation having a microorganism concentration of 200 000-1×107 cells/mL of fluid sample; incubating the formulation for 10 to 120 minutes at a pH of 7 to 12 and a temperature between 18 and 35° C.; and measuring the fluorescence emitted by the formulation, whereby a fluorescence emitted in the sample that is lower than that in a control sample is an indication that the sample contains a bioactive molecule.
Type:
Grant
Filed:
July 31, 2008
Date of Patent:
February 18, 2014
Assignee:
Labbell Inc.
Inventors:
François Bellemare, Lucie Lorrain, Nathalie Boucher
Abstract: A stabilized thylakoid membrane formulation comprising thylakoid membranes in a buffered solution and liposomes, wherein the formulation has a ratio of chlorophyll/liposomes of at least about 10:1. The invention further comprises a method for detecting or quantifying the presence of toxic molecules in a fluid sample, comprising obtaining a stabilized thylakoids membranes formulation; and assessing the photosynthetic efficiency of the thylakoid membranes formulation in the presence of said sample, whereby the molecules are detected when the photosynthetic efficiency is measurably different in the presence versus in the absence of the sample. The present invention also comprises kits using the stabilized thylakoid membranes formulation for detecting and/or quantifying the toxic molecule in a fluid sample.
Type:
Grant
Filed:
April 21, 2010
Date of Patent:
November 6, 2012
Assignee:
Labbell Inc.
Inventors:
François Bellemare, Nathalie Boucher, Lucie Lorrain
Abstract: A method of detecting the presence of bioactive molecules in a fluid sample, comprising contacting a solution of a microorganism selected from the group consisting of a monocellular algae and a cyanobacteria with the fluid sample so as to obtain a formulation having a microorganism concentration of 200 000-1×107 cells/mL of fluid sample; incubating the formulation for 10 to 120 minutes at a pH of 7 to 12 and a temperature between 18 and 35° C.; and measuring the fluorescence emitted by the formulation, whereby a fluorescence emitted in the sample that is lower than that in a control sample is an indication that the sample contains a bioactive molecule.
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