Patents Assigned to Laboratoire Biodim
  • Imidazolo-heteroaryl derivatives with antibacterial properties
    Patent number: 8513250
    Abstract: The invention relates to Imidazolo-heteroaryl derivatives of formula (I). The compounds inhibit the activity of the Dlta enzyme of Gram-positive bacteria and are useful to treat Gram-positive bacterial infections. Furthermore the application discloses method for assessing the Dlta inhibitory activity of tested molecules and a method for measuring the efficacy of molecules in inhibiting bacteria proliferation in vitro.
    Type: Grant
    Filed: March 21, 2008
    Date of Patent: August 20, 2013
    Assignee: Laboratoire Biodim
    Inventors: Sonia Escaich, Alexis Denis, Vincent Gerusz, François Moreau, Mayalen Oxoby, Yannick Bonvin
  • Human immunodeficiency virus integrase—Transportin—SR protein—protein interactions
    Patent number: 8197821
    Abstract: The present invention relates to protein-protein interactions involved in AIDS. More specifically, the present invention relates to complexes of polypeptides or polynucleotides encoding the polypeptides, fragments of the polypeptides, antibodies to the complexes, Selected Interacting Domains (SID®) which are identified due to the protein-protein interactions, methods for screening drugs for agents which modulate the interaction of proteins and pharmaceutical compositions that are capable of modulating the protein-protein interactions.
    Type: Grant
    Filed: February 25, 2008
    Date of Patent: June 12, 2012
    Assignee: Laboratoire Biodim
    Inventors: Pierre Legrain, Jean-Christophe Rain, Richard Benarous, Stéphane Emiliani, Clarissa Berlioz-torrent, Guillaume Blot