Abstract: A monoclonal antibody directed against the human interferon type I receptor (IFN-R), which recognizes the extracellular domain of the human IFN-R and has neutralizing capacity against the biological properties of human type I-IFN. Diagnostic applications for the monoclonal antibody also are provided.
Type:
Grant
Filed:
December 5, 1994
Date of Patent:
July 6, 1999
Assignee:
Laboratoire European De Biotechnologie S.A.
Inventors:
Patrick Benoit, Francois Meyer, Debborah Maguire, Ivan Plavec, Michael G. Tovey