Patents Assigned to LABORATOIRE FRANCAIS DU FRACTIONNEMENT ET DES BIOETCHNOLOGIES
  • Antibody for adcc and inducing cytokine production
    Publication number: 20060127392
    Abstract: The invention concerns chimeric monoclonal antibodies, humanized or human produced in selected cell lines, said antibodies exhibiting high affinity for the CD16 receptor of effector cells of the immune system and hence capable of inducing high ADCC, but also the property of inducing cytokine and interleukin secretion, in particular IFN?, which can enhance the ADCC activity of effector cells and hence be used for treating cancers and infections by pathogenic agents.
    Type: Application
    Filed: September 15, 2003
    Publication date: June 15, 2006
    Applicant: LABORATOIRE FRANCAIS DU FRACTIONNEMENT ET DES BIOETCHNOLOGIES
    Inventors: Christophe de Romeuf, Arnaud Glacet, Jacques Lirochon, Dominique Bourel