Patents Assigned to Laboratoire Francais du Fractionnement et des Biotechnolgies (LFB)
  • Preparation of human, humanized or chimaeric antibodies or polypeptides having different binding profiles to Fcgamma receptors
    Patent number: 7790399
    Abstract: The present invention relates to a method for the production and the selection of human or chimæric or humanized antibodies or molecules that comprise the Fc region of human IgG, capable of modulating the activity of one or several particular Fc receptors, such as the triggering of inhibitory functions through the human type IIB receptors of IgG (FcgammaRIIB/CD32).
    Type: Grant
    Filed: April 5, 2004
    Date of Patent: September 7, 2010
    Assignees: Laboratoire Francais du Fractionnement et des Biotechnolgies (LFB), Institut National de la Sante et de la Recherche Medicale (INSERM)
    Inventors: Dominique Bourel, Christophe De Romeuf, Sophie Siberil, Wolf Herman Fridman, Jean-Luc Teillaud, Nicolas Bihoreau, Emmanuel Nony