Abstract: This galenical formulation which comprises first an outer envelope including gelatin and secondly a non-aqueous liquid or semi-liquid internal phase containing an active principle in solution is characterized in that the active principle is constituted by a spermicide and in that the internal phase includes, in addition to the active principle: a major proportion of a lipophilic agent compatible with the rubber latex of a condom; in minor proportion at least one hydrodispersible agent; at least one bioadhesion agent; and at least one agent for gelling the lipophilic agent. This galenical formulation for vaginal use provides the known advantages of the soft capsule, having properties that are simultaneously spermicidal, antiseptic, and lubricating, and in addition it is reliably compatible with condoms, without any risk of damaging the rubber latex thereof.

Abstract: The therapeutic combination comprises as its associated active ingredients calcium in elemental form and at least one vitamin D. It also contains at least one dry and moist binder combined in synergistic quantity with at least one diluant, at least one binder, and at least one lubricant, at least one of said diluant and said binder being a sweetening agent. Advantageously, the ratio of calcium in elemental form to vitamin D, expressed in mg of elemental Ca per IU of vitamin D lies in the range 1 to 1.5, and preferably in the range 1.2 to 1.3.

Abstract: A galenical formulation is intended for local, essentially non systemic, treatment of vaginal dryness, in particular in the menopausal woman. It comprises a free natural estrogen, in particular a micronized or vectorized estrogen, selected from 17.beta.-estradiol and its salts in solution or in suspension in a lipophilic agent, with an estrogen content which corresponds to an equivalent unit dose of at most 15 .mu.g, preferably less than 10 .mu.g, of 17.beta.-estradiol, a hydrophilic gel-forming bioadhesive agent, a gelling agent for the lipophilic agent and a hydrodispersible agent. The soft capsule form comprises a hard or soft outer envelope containing gelatin and glycerine and a non aqueous liquid or semi-liquid inner phase containing the lipophilic agent with the estrogen in solution or in suspension, the bioadhesive agent and the hydrophilic gelling agent for the lipophilic agent.