Abstract: The present invention relates, by way of new industrial products, to phenylpiperazine derivatives selected from the group comprising 3-methyl-2-phenylpiperazine, 1-isopropyl-3-phenylpiperazine, 1-ethyl-2-methyl-3-phenylpiperazine, 1-isopropyl-2-methyl-3-phenylpiperazine, 1,2,4-trimethyl-3-phenylpiperazine, and (halogenophenyl)alkyl-piperazines of the formula: ##STR1## (wherein X.sub.o is F, Cl or Br, R.sub.1 is H or C.sub.1 -C.sub.4 alkyl, R.sub.2 is H or C.sub.1 -C.sub.2 alkyl and R.sub.3 is H or C.sub.1 -C.sub.4 alkyl, at least one of the symbols R.sub.1, R.sub.2 and R.sub.3 being different from H), and addition salts thereof.These new products are useful as antidepressants for the CNS.