Abstract: The object of this invention is a pharmaceutical composition with a synthetic natural progesterone and oestradiol base coming in the form of a tablet, characterised by the fact that it has a disintegration time of less than 15 minutes, preferably less than 10 minutes, and more preferably still less than 5 minutes.
Abstract: The invention relates to pyrrolo[3,4-b]quinoline derivatives of general formula (I) wherein X represents an oxygen atom or a sulphur atom. Said derivatives have a hypnotic or sedative effect.
Abstract: The invention concerns a progesterone tablet characterised by the fact that its excipient content is at most 45%, preferably at most 40%, and yet more preferably at most 38%, the percentages being expressed in weight relative to the total dry matter of the tablet.
Abstract: A medicament consisting of a biological medium-soluble capsule containing a micronised progesterone suspended in oil is disclosed, characterised in that the capsule also contains estradiol enclosed in microspheres, also suspended in oil, and which consist of one or more polymers that do not dissolve in oil but that dissolve in a biological medium.
Abstract: The invention relates to derivatives of general formula I ##STR1## as defined in the description. The invention also relates to a process for their preparation and to their therapeutic use, in particular or the treatment of complaints associated with melatonin disorders, and pharmaceutical and cosmetic compositions comprising them.
Type:
Grant
Filed:
March 27, 1998
Date of Patent:
December 21, 1999
Assignee:
CEMAF and Laboratoires Besins Iscovesco S.A.
Inventors:
Jean-Bernard Fourtillan, Marianne Fourtillan, Jean-Claude Jacquesy, Marie-Paule Jouannetaud, Bruno Violeau, Omar Karam
Abstract: The present invention is directed to the administration of dihydrotestosterone (DHT) for preventing prostate cancer in male patients more than 50 years old and of reducing levels of plasma-borne sex hormone binding globulins (SHBG) in male patients having elevated levels thereof.