Abstract: A method of therapeutically treating wounds, circulatory insufficiencies and skin disorders, in diabetics, is provided. The method involves the therapeutic application of peroxidized lipids or compositions containing peroxidized lipids to an area of skin of a subject with a diabetic condition including a wound, a skin disorder, or with insufficient circulation. The method is effective for promoting the healing of wounds, in particular, in patients having circulatory insufficiencies and/or diabetes.