Patents Assigned to Laboratoires de Therapeutique Moderne
  • Therapeutic compositions based on 1,2-dithiole-3-thione derivatives
    Patent number: 5750560
    Abstract: The present invention relates to therapeutic compositions based on compounds chosen from the formulae: ##STR1## in which: X is chosen from .dbd.S, .dbd.O, .dbd.SO, .dbd.N--OH, .dbd.N--R.sub.5, .dbd.N--NH--CONH.sub.2, .dbd.N--NH--CSNH.sub.2 and ##STR2## A is chosen from the >C.dbd.N--OH group, a group of formula >C.dbd.N--OR.sub.3, a C.dbd.O group, a group C.dbd.N--R.sub.4 and a CHOH group,and their pharmaceutically acceptable salts.These compositions may be used as free-radical trapping agents.
    Type: Grant
    Filed: November 27, 1995
    Date of Patent: May 12, 1998
    Assignee: Laboratoires De Therapeutique Moderne
    Inventors: Marie-Odile Christen, Jean-Louis Burgot
  • Therapeutic compositions based on 1,2-dithiole-3-thione derivatives
    Patent number: 5470871
    Abstract: The present invention relates to therapeutic compositions based on compounds chosen from the formulae: ##STR1## in which: X is chosen from .dbd.S, .dbd.O, .dbd.SO, .dbd.N--OH, .dbd.N--R.sub.5, .dbd.N--NH--CONH.sub.2, .dbd.N--NH--CSNH.sub.2 and ##STR2## A is chosen from the ##STR3## group, a group of formula ##STR4## a C.dbd.O group, a group C.dbd.N--R.sub.4 and a CHOH group, and their pharmaceutically acceptable salts.These compositions may be used as free-radical trapping agents.
    Type: Grant
    Filed: December 27, 1993
    Date of Patent: November 28, 1995
    Assignee: Laboratoires de Therapeutique Moderne
    Inventors: Marie-Odile Christen, Jean-Louis Burgot