Patents Assigned to Laboratoires Delagrange
  • Patent number: 5141949
    Abstract: Anxiolytic and antipsychotic treatment is provided to patients by administering therapeutically effective amounts of N-[2-(diethylamino)-ethyl]-2-methoxy-4-[(1-H-4,5-dihydro-2-imidazolyl)-ami no]-5-chlorobenzamide, or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: October 31, 1991
    Date of Patent: August 25, 1992
    Assignee: Laboratoires Delagrange (Synthelabo)
    Inventors: Jacques Acher, Jean-Claude Monier, Jean-Paul Schmitt, Brenda Costall, Robert Naylor, Renee Gardaix-Luthereau
  • Patent number: 5116859
    Abstract: Anxiolytic and antipsychotic treatment is provided to patients by administering therapeutically effective amounts of N-[2-(diethylamino)-ethyl]-2-methoxy-4-[(1-H-4,5-dihydro-2-immidazolyl)-am ino]-5-chlorobenzamide, or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: June 17, 1988
    Date of Patent: May 26, 1992
    Assignee: Laboratoires Delagrange Societe d'Application Pharmacodynamiques
    Inventors: Jacques Acher, Jean-Claude Monier, Jean-Paul Schmitt, Brenda Costall, Robert Naylor, Renee Gardaix-Luthereau
  • Patent number: 5116857
    Abstract: The present invention relates to the use of substituted benzamides of formula (1): ##STR1## in which: A is linear or branched C.sub.1 -C.sub.3 alkyl; allyl or diethylaminoethyl;R.sub.1 is hydrogen or methyl, andZ-- is --NH--, --O-- or --S--,and of their pharmacologically acceptable salts for modifying gastric motility.
    Type: Grant
    Filed: December 14, 1989
    Date of Patent: May 26, 1992
    Assignee: Laboratoires Delagrange Div. Societe d'Applications Pharmacodynamiques
    Inventors: Jacques Acher, Jean-Claude Monier, Jean-Paul Schmitt, Brenda Costall, Robert Naylor, Renee Gardaix-Luthereau
  • Patent number: 5086066
    Abstract: The present invention relates to the application of substituted benzamides of formula (I): ##STR1## in which: A is diethylaminoethyl, 1-ethyl-2-pyrrolidinylmethyl or 1-allyl-2-pyrrolidinylmethyl;R.sub.1 is hydrogen or methyl;X is chlorine or bromine;Z is --NH-- or --O-- except when Z is --NH--,R.sub.1 is hydrogen and X is chlorine, and of their pharmacologically acceptable addition salts, as anxiolytics and antipsychotics.
    Type: Grant
    Filed: December 20, 1989
    Date of Patent: February 4, 1992
    Assignee: Laboratoires Delagrange Societe d'Applications Pharmacodnymiques
    Inventors: Jacques Acher, Jean-Claude Monier, Jean-Paul Schmitt, Renee Gardaix-Luthereau, Robert Naylor, Brenda Costall
  • Patent number: 5006570
    Abstract: The invention relates to new dihydrobenzofuran- and chroman-carboxamide derivatives of the general formula: ##STR1## in which R and R' are each hydrogen or methyl; n is 1 or 2; m is 1 or 2; Z is either ##STR2## wherein R.sub.1 and R.sub.2 are lower alkyl, or ##STR3## wherein R.sub.3 is alkyl, alkenyl, cycloalkyl-alkyl, cycloalkenyl-alkyl, X is H, NH.sub.2, methoxy, or methyl and Y is H, Cl, cycloalkylmethylsulfonyl, alkylsulfamoyl or alkylsulfonyland to their pharmacologically acceptable acid addition salts and their optical isomers, to the processes for the preparation thereof and to the use thereof as medicaments, especially as neuroleptics.
    Type: Grant
    Filed: January 30, 1987
    Date of Patent: April 9, 1991
    Assignee: Laboratoires Delagrange
    Inventors: Jacqueline Franceschini, Josette Margarit