Patents Assigned to Laboratoires Expanscience
  • Patent number: 12109245
    Abstract: The invention relates to an extract of aerial parts of Maca rich in polyphenols, and also to a composition comprising such an extract and, where appropriate, a suitable excipient. The invention also relates to a process for extracting an extract of aerial parts of Maca rich in polyphenols, and also to the extract that can be obtained by means of said process. The invention also relates to such a composition or such an extract for use thereof in preventing or treating disorders or pathological conditions of the skin, the mucous membranes or the superficial body growths and/or for use thereof in preventing and/or treating vascular disorders. Finally, the invention relates to a cosmetic care process for the skin, the superficial body growths or the mucous membranes, with a view to improving the condition thereof or the appearance thereof, which comprises the administration of such a composition or of such an extract.
    Type: Grant
    Filed: September 24, 2019
    Date of Patent: October 8, 2024
    Assignee: Laboratoires Expanscience
    Inventors: Alex Saunois, Caroline Baudouin, Sophie Leclere-Bienfait, Sebastien Garnier, Philippe Msika
  • Patent number: 12061189
    Abstract: The present invention relates to models of reconstructed sensitive skin reproducing the features of sensitive skin, as well as to processes for obtaining such models. The present invention further relates to in vitro processes for testing formulations or active ingredients for the prevention or treatment of sensitive skin.
    Type: Grant
    Filed: June 21, 2018
    Date of Patent: August 13, 2024
    Assignee: Laboratoires Expanscience
    Inventors: Gaelle Bellemere, Stephanie Bredif, Gaetan Boyer, Caroline Baudouin
  • Publication number: 20240091294
    Abstract: The invention relates to an extract of top growth of holy basil, in particular of Ocimum sanctum, a method for preparing the extract, and the extract obtainable by said method. The invention also relates to a composition comprising such an extract, the composition advantageously being a cosmetic, pharmaceutical or dermatological composition. The invention also relates to such a composition or such an extract for use in preventing or treating disorders or diseases of the skin, the mucous membranes or the skin appendages, and for use in preventing or treating vascular disorders. Finallyc the invention relates to a cosmetic care method for the skin, skin appendages or mucous membranes, with a view to improving the condition or appearance thereof, which method consists in administering such a composition or such an extract.
    Type: Application
    Filed: January 20, 2022
    Publication date: March 21, 2024
    Applicant: Laboratoires Expanscience
    Inventors: Sophie LECLERE-BIENFAIT, Stephanie BREDIF
  • Patent number: 11892447
    Abstract: The invention relates to biomarkers in children's skin, in particular in the skin of infants, the expression of which changes when the skin is dry. Such markers are particularly advantageous in that they allow the skin's response to dehydration to be monitored. The inventors have developed methods for evaluating the in vitro efficacy of formulations in preventing the effects of dehydration on children's skin, using a skin model specifically capable of reproducing the characteristics of children's skin.
    Type: Grant
    Filed: December 16, 2016
    Date of Patent: February 6, 2024
    Assignee: Laboratoires Expanscience
    Inventors: Stephanie Bredif, Caroline Baudouin
  • Publication number: 20230277613
    Abstract: The invention relates to an extract from the flowers, preferably from the calyxes, of Bombax costatum, to a process for preparing same and to the extract obtained by said process. The invention also relates to a composition comprising such an extract, the composition advantageously being a cosmetic, pharmaceutical or dermatological composition. The invention also relates to such a composition or such an extract for the use thereof in preventing or treating disorders or pathological conditions of the skin, the mucous membranes or the hair and nails, as well as the imbalance or disorders associated with the imbalance of the microbiota of the skin, the mucous membranes, the hair, the nails and associated skin appendages. Finally, the invention relates to a cosmetic care method for the skin, the hair and nails or the mucous membranes, with a view to improving the condition or the appearance thereof, which method consists in administering such a composition or such an extract.
    Type: Application
    Filed: July 26, 2021
    Publication date: September 7, 2023
    Applicant: Laboratoires Expanscience
    Inventors: Sophie LECLERE-BIENFAIT, Stephanie BREDIF
  • Patent number: 11604184
    Abstract: The invention relates to biomarkers in children's skin, in particular in the skin of infants, the expression of which changes when the skin is affected by atopic dermatitis. Such markers are particularly advantageous in that they allow the skin's response to atopic dermatitis to be monitored. The inventors have developed methods for evaluating the in vitro efficacy of formulations in preventing the effects of atopic dermatitis on a child's skin, using a skin model specifically capable of reproducing the characteristics of children's skin.
    Type: Grant
    Filed: June 23, 2017
    Date of Patent: March 14, 2023
    Assignee: Laboratoires Expanscience
    Inventors: Caroline Baudouin, Stephanie Bredif
  • Publication number: 20220249446
    Abstract: The present invention relates to a composition comprising at least one oxazoline, such as OX100, for inhibiting the growth of Malassezia yeasts and/or for preventing and/or treating conditions caused by Malassezia yeasts, seborrheic dermatitis, cradle cap, Malassezia folliculitis, dandruff, Pityriasis versicolor or Pityriasis capitis. The present invention also relates to a composition comprising at least one oxazoline such as OX100, at least one compound such as malic acid diester and a vegetable oil oleodistillate and/or arabinogalactan, and to the use of same for preventing and/or treating, in particular, affections caused by Malassezia yeasts, seborrheic dermatitis, cradle cap, Malassezia folliculitis, dandruff, Pityriasis versicolor or Pityriasis capitis.
    Type: Application
    Filed: July 13, 2020
    Publication date: August 11, 2022
    Applicant: Laboratoires Expanscience
    Inventors: Stephanie BREDIF, Sophie LECLERE-BIENFAIT, David DURANCET
  • Publication number: 20220071891
    Abstract: The invention relates to a peptide extract of the microalga Chlamydomonas acidophila, and to a method for the preparation thereof. The invention also relates to a composition, advantageously a cosmetic or dermatological composition, comprising such an extract. The invention also relates to such a composition or such an extract for use in the prevention or treatment of disorders or diseases affecting the skin, mucous membranes or skin appendages, for use in the prevention or treatment of vascular disorders, or else for use in the prevention or treatment of adipose tissue modifications. The invention finally relates to a cosmetic care process for the skin, the skin appendages or the mucous membranes, with a view to improving the condition thereof or the appearance thereof, which process consists in administering such a composition or such an extract.
    Type: Application
    Filed: December 30, 2019
    Publication date: March 10, 2022
    Applicant: Laboratoires Expanscience
    Inventors: Sophie LECLERE-BIENFAIT, Stephanie BREDIF
  • Publication number: 20220039414
    Abstract: The present invention concerns a method for preparing dehydrated avocados, a method for preparing an unsaponifiable-rich avocado oil, a method for preparing an avocado cake rich in sugars and proteins, and a method for preparing an unsaponifiable fraction; these methods all comprising a step of drying avocado slices by means of microwaves until dehydrated avocados are obtained having residual moisture less than or equal to 5%; during this step, the water evaporated under the action of the microwaves being eliminated by a warm air stream with a temperature less than or equal to 80° C. and/or by air extraction.
    Type: Application
    Filed: September 27, 2019
    Publication date: February 10, 2022
    Applicant: Laboratoires Expanscience
    Inventors: Gaelle Le Crouerour, Delphine Taupin, Iann Rance
  • Publication number: 20210093685
    Abstract: The invention relates to an extract of flowers, preferably calyxes, from kapok trees, in particular Bombax costatum, to a process for preparing same and to the extract obtainable by said process. The invention also relates to a composition comprising such an extract, the composition being advantageously a cosmetic, pharmaceutical or dermatological composition. The invention also relates to such a composition or such an extract for use in preventing or treating disorders or diseases of the skin, the mucous membranes or keratinous appendages and for use in preventing or treating vascular disorders. The invention finally relates to a cosmetic care process for the skin, the keratinous appendages or the mucous membranes, with a view to improving the condition thereof or the appearance thereof, which process consists in administering such a composition or such an extract.
    Type: Application
    Filed: December 21, 2018
    Publication date: April 1, 2021
    Applicant: Laboratoires Expanscience
    Inventors: Sophie Leclere-Bienfait, Stéphanie Bredif
  • Publication number: 20200011854
    Abstract: The present invention relates to a method for determining the isotropy of the skin surface of a subject, and hence the degree of maturation of the said skin surface, by examining various parameters reflecting the cell organization. Methods for identifying active agents, raw materials and formulation are also provided.
    Type: Application
    Filed: September 6, 2019
    Publication date: January 9, 2020
    Applicant: Laboratoires Expanscience
    Inventors: Philippe MSIKA, Nadege LACHMANN, Joachim FLUHR
  • Publication number: 20190242880
    Abstract: The invention relates to biomarkers in children's skin, in particular in the skin of infants, the expression of which changes when the skin is dry. Such markers are particularly advantageous in that they allow the skin's response to dehydration to be monitored. The inventors have developed methods for evaluating the in vitro efficacy of formulations in preventing the effects of dehydration on children's skin, using a skin model specifically capable of reproducing the characteristics of children's skin.
    Type: Application
    Filed: December 16, 2016
    Publication date: August 8, 2019
    Applicant: Laboratoires Expanscience
    Inventors: Stephanie BREDIF, Caroline BAUDOUIN
  • Publication number: 20190234939
    Abstract: The invention relates to biomarkers in children's skin, in particular in the skin of infants, the expression of which changes when the skin is affected by atopic dermatitis. Such markers are particularly advantageous in that they allow the skin's response to atopic dermatitis to be monitored. The inventors have developed methods for evaluating the in vitro efficacy of formulations in preventing the effects of atopic dermatitis on a child's skin, using a skin model specifically capable of reproducing the characteristics of children's skin.
    Type: Application
    Filed: June 23, 2017
    Publication date: August 1, 2019
    Applicant: Laboratoires Expanscience
    Inventors: Caroline BAUDOUIN, Stephanie BREDIF
  • Publication number: 20190209631
    Abstract: The invention relates to a lipid extract of the seeds of passion fruit, Passiflora incarnata and/or Passiflora edulis, preferably P. edulis, characterised in that said lipid extract is an oil of passion fruit seeds concentrated in its unsaponifiable fraction, containing between 3 wt. % and 100 wt. % of unsaponifiable matter in relation to the total weight of the extract. The invention also relates to a method for preparing such an extract and to a composition comprising said extract, especially for the use thereof in a dermatological or pharmaceutical composition or as a food.
    Type: Application
    Filed: January 9, 2019
    Publication date: July 11, 2019
    Applicant: Laboratoires Expanscience
    Inventors: Sophie LECLERE-BIENFAIT, Stephanie BREDIF, Sebastien DEBROCK, Sebastien GARNIER
  • Publication number: 20190008757
    Abstract: The invention relates to a cosmetic or dermatological composition containing a polyphenol-enriched extract of Vitex Negundo, typically a root extract obtained using a PAT plant milking®process. The invention further relates to a composition of this kind for use in the prevention or treatment of disorders and diseases affecting the skin, mucous membranes or skin appendages, for use in the prevention or treatment of vascular disorders and for use in the prevention or treatment of extrinsic or intrinsic skin aging. Lastly, the invention relates to a cosmetic care method for the skin, skin appendages or mucous membranes, with a view to improving the condition or appearance thereof, said method consisting in administering such a composition or such an extract.
    Type: Application
    Filed: January 27, 2017
    Publication date: January 10, 2019
    Applicant: Laboratoires Expanscience
    Inventors: Sophie LECLERE-BIENFAIT, Philippe MSIKA
  • Publication number: 20180369193
    Abstract: The invention relates to an avocado extract rich in polyphenols, containing at least 10% by weight of polyphenols, expressed in gallic acid equivalent relative to the dry extract obtained, wherein said polyphenols contain procyanidins, cafeic acid and cafeic acid derivatives, typically in a proportion of at least 70% by weight, expressed in gallic acid equivalent relative to the total polyphenol content by weight. The invention also relates to a composition comprising an extract according to the invention as active agent and a suitable excipient. The invention also relates to such a composition or such an extract for use thereof in preventing or treating disorders or pathological conditions of the skin, the mucous membranes or the superficial body growths.
    Type: Application
    Filed: August 30, 2018
    Publication date: December 27, 2018
    Applicant: Laboratoires Expanscience
    Inventors: Alex SAUNOIS, Caroline BAUDOUIN, Sophie LECLERE-BIENFAIT, Sebastien GARNIER, Philippe MSIKA
  • Publication number: 20180149640
    Abstract: The invention relates to biomarkers of the skin of children and, in particular, that of infants, having altered expression in the presence of urine. Such markers are particularly advantageous as they allow the skin's response to urine to be monitored. The inventors have developed methods for evaluating the efficacy in vitro of formulations in preventing the harmful effects of urine on a child's skin, using a skin model specifically capable of reproducing the characteristics of children's skin.
    Type: Application
    Filed: March 31, 2015
    Publication date: May 31, 2018
    Applicant: Laboratoire Expanscience
    Inventors: Caroline BAUDOUIN, Philippe MSIKA
  • Patent number: 9909084
    Abstract: The present invention relates to an extraction process of an unsaponifiable fraction contained in an oil or a vegetable butter, in an oil originating from a micro-organism, in a concentrate of oil or butter or of oil originating from a micro-organism, or in a co-product of the refining industry for vegetable oils, such as deodorization exhaust and distillates of physical refining, or oils originating from micro-organisms, comprising at least: A) a transformation step of said oils, of said butter or said co-product of the refining industry for vegetable oils or oils originating from micro-organisms in hydro-alcoholic solution, especially via a saponification step, and B) an extraction step of the hydro-alcoholic solution in which the fatty fraction is separated from unsaponifiable fraction by liquid/liquid extraction, said process being characterized in that at least the liquid/liquid extraction step of the step B is performed by using a first solvent system comprising a solvent content selected from the s
    Type: Grant
    Filed: July 30, 2012
    Date of Patent: March 6, 2018
    Assignee: Laboratoires Expanscience
    Inventors: Eglantine Mercier, Jacques Legrand, Alex Saunois
  • Publication number: 20170241985
    Abstract: The present invention relates to a method for determining the relief of the skin surface of a subject, and hence the degree of maturation of the said skin surface. Methods for identifying active agents, raw materials and formulation are also provided.
    Type: Application
    Filed: May 15, 2015
    Publication date: August 24, 2017
    Applicant: Laboratoires Expanscience
    Inventors: Nadege Lachman, Philippe MSIKA, Joachim Fluhr
  • Publication number: 20160326492
    Abstract: A first subject of the invention is a skin model characterized in that it comprises keratinocytes capable of overexpressing filaggrin.
    Type: Application
    Filed: January 12, 2015
    Publication date: November 10, 2016
    Applicant: Laboratoires Expanscience
    Inventors: Stephanie BREDIF, Caroline BAUDOUIN, Philippe MSIKA, Marisa MELONI