Patents Assigned to Laboratoires Expanscience
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Publication number: 20240091294Abstract: The invention relates to an extract of top growth of holy basil, in particular of Ocimum sanctum, a method for preparing the extract, and the extract obtainable by said method. The invention also relates to a composition comprising such an extract, the composition advantageously being a cosmetic, pharmaceutical or dermatological composition. The invention also relates to such a composition or such an extract for use in preventing or treating disorders or diseases of the skin, the mucous membranes or the skin appendages, and for use in preventing or treating vascular disorders. Finallyc the invention relates to a cosmetic care method for the skin, skin appendages or mucous membranes, with a view to improving the condition or appearance thereof, which method consists in administering such a composition or such an extract.Type: ApplicationFiled: January 20, 2022Publication date: March 21, 2024Applicant: Laboratoires ExpanscienceInventors: Sophie LECLERE-BIENFAIT, Stephanie BREDIF
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Patent number: 11892447Abstract: The invention relates to biomarkers in children's skin, in particular in the skin of infants, the expression of which changes when the skin is dry. Such markers are particularly advantageous in that they allow the skin's response to dehydration to be monitored. The inventors have developed methods for evaluating the in vitro efficacy of formulations in preventing the effects of dehydration on children's skin, using a skin model specifically capable of reproducing the characteristics of children's skin.Type: GrantFiled: December 16, 2016Date of Patent: February 6, 2024Assignee: Laboratoires ExpanscienceInventors: Stephanie Bredif, Caroline Baudouin
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Publication number: 20230277613Abstract: The invention relates to an extract from the flowers, preferably from the calyxes, of Bombax costatum, to a process for preparing same and to the extract obtained by said process. The invention also relates to a composition comprising such an extract, the composition advantageously being a cosmetic, pharmaceutical or dermatological composition. The invention also relates to such a composition or such an extract for the use thereof in preventing or treating disorders or pathological conditions of the skin, the mucous membranes or the hair and nails, as well as the imbalance or disorders associated with the imbalance of the microbiota of the skin, the mucous membranes, the hair, the nails and associated skin appendages. Finally, the invention relates to a cosmetic care method for the skin, the hair and nails or the mucous membranes, with a view to improving the condition or the appearance thereof, which method consists in administering such a composition or such an extract.Type: ApplicationFiled: July 26, 2021Publication date: September 7, 2023Applicant: Laboratoires ExpanscienceInventors: Sophie LECLERE-BIENFAIT, Stephanie BREDIF
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Patent number: 11604184Abstract: The invention relates to biomarkers in children's skin, in particular in the skin of infants, the expression of which changes when the skin is affected by atopic dermatitis. Such markers are particularly advantageous in that they allow the skin's response to atopic dermatitis to be monitored. The inventors have developed methods for evaluating the in vitro efficacy of formulations in preventing the effects of atopic dermatitis on a child's skin, using a skin model specifically capable of reproducing the characteristics of children's skin.Type: GrantFiled: June 23, 2017Date of Patent: March 14, 2023Assignee: Laboratoires ExpanscienceInventors: Caroline Baudouin, Stephanie Bredif
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Patent number: 11596662Abstract: The invention relates to a polyphenolic extract of passion flower seeds, in particular Passiflora incarnata or Passiflora edulis seeds, comprising at least 30 percent by weight polyphenols, expressed as gallic acid equivalent, relative to the weight of the dry extract. The invention also relates to a method for preparing an extract of said type, a composition containing same, and the cosmetic, dermatological or therapeutic use thereof.Type: GrantFiled: April 23, 2021Date of Patent: March 7, 2023Assignee: LABORATOIRES EXPANSCIENCEInventors: Sophie Leclere-Bienfait, Stéphanie Bredif
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Publication number: 20220249446Abstract: The present invention relates to a composition comprising at least one oxazoline, such as OX100, for inhibiting the growth of Malassezia yeasts and/or for preventing and/or treating conditions caused by Malassezia yeasts, seborrheic dermatitis, cradle cap, Malassezia folliculitis, dandruff, Pityriasis versicolor or Pityriasis capitis. The present invention also relates to a composition comprising at least one oxazoline such as OX100, at least one compound such as malic acid diester and a vegetable oil oleodistillate and/or arabinogalactan, and to the use of same for preventing and/or treating, in particular, affections caused by Malassezia yeasts, seborrheic dermatitis, cradle cap, Malassezia folliculitis, dandruff, Pityriasis versicolor or Pityriasis capitis.Type: ApplicationFiled: July 13, 2020Publication date: August 11, 2022Applicant: Laboratoires ExpanscienceInventors: Stephanie BREDIF, Sophie LECLERE-BIENFAIT, David DURANCET
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Publication number: 20220071891Abstract: The invention relates to a peptide extract of the microalga Chlamydomonas acidophila, and to a method for the preparation thereof. The invention also relates to a composition, advantageously a cosmetic or dermatological composition, comprising such an extract. The invention also relates to such a composition or such an extract for use in the prevention or treatment of disorders or diseases affecting the skin, mucous membranes or skin appendages, for use in the prevention or treatment of vascular disorders, or else for use in the prevention or treatment of adipose tissue modifications. The invention finally relates to a cosmetic care process for the skin, the skin appendages or the mucous membranes, with a view to improving the condition thereof or the appearance thereof, which process consists in administering such a composition or such an extract.Type: ApplicationFiled: December 30, 2019Publication date: March 10, 2022Applicant: Laboratoires ExpanscienceInventors: Sophie LECLERE-BIENFAIT, Stephanie BREDIF
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Publication number: 20220039414Abstract: The present invention concerns a method for preparing dehydrated avocados, a method for preparing an unsaponifiable-rich avocado oil, a method for preparing an avocado cake rich in sugars and proteins, and a method for preparing an unsaponifiable fraction; these methods all comprising a step of drying avocado slices by means of microwaves until dehydrated avocados are obtained having residual moisture less than or equal to 5%; during this step, the water evaporated under the action of the microwaves being eliminated by a warm air stream with a temperature less than or equal to 80° C. and/or by air extraction.Type: ApplicationFiled: September 27, 2019Publication date: February 10, 2022Applicant: Laboratoires ExpanscienceInventors: Gaelle Le Crouerour, Delphine Taupin, Iann Rance
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Publication number: 20210236574Abstract: The invention relates to a polyphenolic extract of passion flower seeds, in particular Passiflora incarnata or Passiflora edulis seeds, comprising at least 30 percent by weight polyphenols, expressed as gallic acid equivalent, relative to the weight of the dry extract. The invention also relates to a method for preparing an extract of said type, a composition containing same, and the cosmetic, dermatological or therapeutic use thereof.Type: ApplicationFiled: April 23, 2021Publication date: August 5, 2021Applicant: LABORATOIRES EXPANSCIENCEInventors: Sophie LECLERE-BIENFAIT, Stéphanie BREDIF
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Patent number: 11026880Abstract: The invention relates to a composition comprising an extract of passionflower seeds, and preferentially Passiflora edulis seeds. The composition is advantageously cosmetic, pharmaceutical, dermatological or nutraceutical. The subject matter of the invention is also a process for extracting an extract of passionflower seeds and preferentially Passiflora edulis seeds, and also the extract which can be obtained by means of said process. The invention also relates to such a composition or such an extract for use in the prevention or treatment of disorders or pathological conditions of the skin, of the mucous membranes or of the skin appendages, for use in the prevention or treatment of vascular disorders, for use for combating oxidative stress, or else for use in the prevention or treatment of adipose tissue modifications.Type: GrantFiled: December 18, 2013Date of Patent: June 8, 2021Assignee: LABORATOIRES EXPANSCIENCEInventors: Philippe Msika, Sophie Leclere-Bienfait, Sebastien Debrock, Stephanie Bredif, Sebastien Garnier
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Patent number: 11026441Abstract: The invention relates to an avocado extract rich in polyphenols, containing at least 10% by weight of polyphenols, expressed in gallic acid equivalent relative to the dry extract obtained, wherein said polyphenols contain procyanidins, cafeic acid and cafeic acid derivatives, typically in a proportion of at least 70% by weight, expressed in gallic acid equivalent relative to the total polyphenol content by weight. The invention also relates to a composition comprising an extract according to the invention as active agent and a suitable excipient. The invention also relates to such a composition or such an extract for use thereof in preventing or treating disorders or pathological conditions of the skin, the mucous membranes or the superficial body growths.Type: GrantFiled: August 30, 2018Date of Patent: June 8, 2021Assignee: LABORATOIRES EXPANSCIENCEInventors: Alex Saunois, Caroline Baudouin, Sophie Leclere-Bienfait, Sebastien Garnier, Philippe Msika
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Publication number: 20210093685Abstract: The invention relates to an extract of flowers, preferably calyxes, from kapok trees, in particular Bombax costatum, to a process for preparing same and to the extract obtainable by said process. The invention also relates to a composition comprising such an extract, the composition being advantageously a cosmetic, pharmaceutical or dermatological composition. The invention also relates to such a composition or such an extract for use in preventing or treating disorders or diseases of the skin, the mucous membranes or keratinous appendages and for use in preventing or treating vascular disorders. The invention finally relates to a cosmetic care process for the skin, the keratinous appendages or the mucous membranes, with a view to improving the condition thereof or the appearance thereof, which process consists in administering such a composition or such an extract.Type: ApplicationFiled: December 21, 2018Publication date: April 1, 2021Applicant: Laboratoires ExpanscienceInventors: Sophie Leclere-Bienfait, Stéphanie Bredif
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Patent number: 10837958Abstract: The invention relates to biomarkers of the skin of children and, in particular, that of infants, having altered expression in the presence of urine. Such markers are particularly advantageous as they allow the skin's response to urine to be monitored. The inventors have developed methods for evaluating the efficacy in vitro of formulations in preventing the harmful effects of urine on a child's skin, using a skin model specifically capable of reproducing the characteristics of children's skin.Type: GrantFiled: March 31, 2015Date of Patent: November 17, 2020Assignee: LABORATOIRES EXPANSCIENCEInventors: Caroline Baudouin, Philippe Msika
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Publication number: 20200256853Abstract: The present invention relates to models of reconstructed sensitive skin reproducing the features of sensitive skin, as well as to processes for obtaining such models. The present invention further relates to in vitro processes for testing formulations or active ingredients for the prevention or treatment of sensitive skin.Type: ApplicationFiled: June 21, 2018Publication date: August 13, 2020Applicant: LABORATOIRES EXPANSCIENCEInventors: Gaelle BELLEMERE, Stephanie BREDIF, Gaetan BOYER, Caroline BAUDOUIN
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Patent number: 10688142Abstract: A method to treat skin or mucosa cells or disorders related to dermal tissue by topically administering to a person in a need thereof a lipid extract from Passiflora seeds selected from Passiflora incarnate seeds, Passiflora edulis seeds, and a combination thereof, wherein said lipid extract is oil of Passiflora seeds concentrated in its unsaponifiable fraction containing 3 to 100 weight % of unsaponifiables relative to the total weight of the extract.Type: GrantFiled: January 9, 2019Date of Patent: June 23, 2020Assignee: LABORATOIRES EXPANSCIENCEInventors: Sophie Leclere-Bienfait, Stephanie Bredif, Sebastien Debrock, Sebastien Garnier
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Patent number: 10620189Abstract: The present invention relates to a method for determining the isotropy of the skin surface of a subject, and hence the degree of maturation of the said skin surface, by examining various parameters reflecting the cell organization. Methods for identifying active agents, raw materials and formulation are also provided.Type: GrantFiled: September 6, 2019Date of Patent: April 14, 2020Assignee: LABORATOIRES EXPANSCIENCEInventors: Philippe Msika, Nadege Lachmann, Joachim Fluhr
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Publication number: 20200085897Abstract: The invention relates to an extract of aerial parts of Maca rich in polyphenols, and also to a composition comprising such an extract and, where appropriate, a suitable excipient. The invention also relates to a process for extracting an extract of aerial parts of Maca rich in polyphenols, and also to the extract that can be obtained by means of said process. The invention also relates to such a composition or such an extract for use thereof in preventing or treating disorders or pathological conditions of the skin, the mucous membranes or the superficial body growths and/or for use thereof in preventing and/or treating vascular disorders. Finally, the invention relates to a cosmetic care process for the skin, the superficial body growths or the mucous membranes, with a view to improving the condition thereof or the appearance thereof, which comprises the administration of such a composition or of such an extract.Type: ApplicationFiled: September 24, 2019Publication date: March 19, 2020Applicant: LABORATOIRES EXPANSCIENCEInventors: Alex SAUNOIS, Caroline BAUDOUIN, Sophie LECLERE-BIENFAIT, Sebastien GARNIER, Philippe MSIKA
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Publication number: 20200011854Abstract: The present invention relates to a method for determining the isotropy of the skin surface of a subject, and hence the degree of maturation of the said skin surface, by examining various parameters reflecting the cell organization. Methods for identifying active agents, raw materials and formulation are also provided.Type: ApplicationFiled: September 6, 2019Publication date: January 9, 2020Applicant: Laboratoires ExpanscienceInventors: Philippe MSIKA, Nadege LACHMANN, Joachim FLUHR
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Patent number: 10463593Abstract: The present invention relates to the use of a lupin peptide extract to prevent loss of skin firmness or to increase the firmness of skin. Advantageously, the lupin peptide extract can prevent the appearance of cellulite and/or reduce skin cellulite.Type: GrantFiled: July 3, 2015Date of Patent: November 5, 2019Assignee: LABORATOIRES EXPANSCIENCEInventors: Caroline Baudouin, Sophie Leclere-Bienfait, Philippe Msika, Stéphanie Bredif
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Patent number: 10458977Abstract: The present invention relates to a method for determining the relief of the skin surface of a subject, and hence the degree of maturation of the said skin surface. Methods for identifying active agents, raw materials and formulation are also provided.Type: GrantFiled: May 15, 2015Date of Patent: October 29, 2019Assignee: LABORATOIRES EXPANSCIENCEInventors: Nadege Lachman, Philippe Msika, Joachim Fluhr