Patents Assigned to Laboratoires Sarget
  • Patent number: 5081137
    Abstract: The present invention concerns amino-2 aryloxymethyl-5 oxazolines having the structure: ##STR1## wherein the aryl group Ar is choosen from the group consisting in phenyl-2 phenyl, phenyl-3 and phenyl-4 phenyl. The compounds according to the invention are useful as medicines.
    Type: Grant
    Filed: April 11, 1990
    Date of Patent: January 14, 1992
    Assignee: Laboratoires SARGET
    Inventors: Patrick Descas, Emmanuel Panconi, Christian Jarry
  • Patent number: 4760139
    Abstract: The present invention relates to a novel method of preparing D-ribose.In this method, a 1,5-di-O-alkyl derivative of D-xylofuranose is prepared; the hydroxyl groups in positions 2 and 3 are each substituted by a group which is preferably mesyl (CH.sub.3 SO.sub.2) or methyldithiocarbonyl, CH.sub.3 SC(=S); the 2,3-unsaturated derivative is prepared; and D-ribose is finally obtained by cis-hydoxylation of the carbon-carbon double bond, followed by acid hydrolysis of the resulting 1,5-O-dialkyl derivative.
    Type: Grant
    Filed: September 22, 1986
    Date of Patent: July 26, 1988
    Assignee: Laboratoires Sarget
    Inventors: Claude Feniou, Micheline Grignon, Brigitte Lacourt, Henri Pontagnier, Bernadette Rezzonico
  • Patent number: 4335113
    Abstract: The present invention concerns a new triterpenic saponin derived from caulophyllogenin, the process for extracting it from varieties of Chrysanthellum, and its therapeutic use.This saponin is characterized as being the ester of O-.beta.-D-glucosyl-3.beta.-caulophyllogenin and an oligosaccharide comprising two units of L-rhamnose and two units of D-xylose. It is extracted from vegetable matter and purified using pressurized liquid preparative chromatographic techniques.This saponin is useful in human and veterinary therapeutics in phlebology, rheumatology, and traumatology.
    Type: Grant
    Filed: May 12, 1980
    Date of Patent: June 15, 1982
    Assignee: Laboratoires Sarget
    Inventors: Henri Combier, Gisele Prat, Henri Pontagnier
  • Patent number: 4333930
    Abstract: Compounds, exhibiting central nervous system activity, of the formula ##STR1## wherein R.sub.1 is phenyl which is unsubstituted or substituted by at least one member selected from the group consisting of halogen, CF.sub.3, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy and COOH, orR.sub.1 is ##STR2## or R.sub.1 is a heterocycle selected from the group consisting of ##STR3## R.sub.2 R.sub.3 R.sub.4 and R.sub.5, which may be identical or different, are H or CH.sub.3 ;R.sub.6 and R.sub.7, which may be identical or different, are C.sub.1 -C.sub.6 alkyl, which may be straight-chained or branched, orR.sub.7 can be H when R.sub.6 is a branched-chain alkyl, orR.sub.6 and R.sub.7 can form, with the nitrogen to which they are bonded, a heterocycle selected from the group consisting of ##STR4## R.sub.8 R.sub.9 R.sub.10 and R.sub.11, which may be identical or different, are H, halogen, CF.sub.3, hydroxy or C.sub.1 -C.sub.4 alkoxy, or two contiguous members of R.sub.8 R.sub.9, R.sub.10 and R.sub.
    Type: Grant
    Filed: February 23, 1981
    Date of Patent: June 8, 1982
    Assignee: Laboratoires Sarget
    Inventors: Marie-Helene Creuzet, Claude Feniou, Francoise Guichard, Gisele Prat
  • Patent number: 4333938
    Abstract: New compounds of the general formula: ##STR1## wherein R.sub.1 is an unsaturated heterocyclic radical selected from the group consisting of: ##STR2## wherein R.sub.2 is H or one substituent selected from the group consisting of CH.sub.3, halogen, and nitro, are useful as anti-inflammatories and in the oral treatment of diabetes.
    Type: Grant
    Filed: June 25, 1980
    Date of Patent: June 8, 1982
    Assignee: Laboratoires Sarget
    Inventors: Marie-Helene Creuzet, Claude Feniou, Gisele Prat, Henri Pontagnier
  • Patent number: 4211772
    Abstract: Acetals and ketals of benzopyran glycosides, prepared by condensing a benzopyran glycoside with a carbonyl compound using a chloroformate ester as condensing agent, show enhanced activity in treating capillary fragility and related pathologies, as well as effectiveness in modifying the evolution of diabetic cataracts.
    Type: Grant
    Filed: June 1, 1978
    Date of Patent: July 8, 1980
    Assignee: Laboratoires Sarget
    Inventors: Francois Fauran, Claude Feniou, Jacqueline Mosser, Annie Thibault, Claude Andre, Gisele Prat
  • Patent number: 4179519
    Abstract: A method for reducing serum lipid levels in humans and animals is provided which comprises administering a hypolipidemically effective amount of p-chlorophenyl 2-(p-chlorophenoxy)-2-methylpropionate. A hypolipidemic composition is provided which comprises p-chlorophenyl 2-(p-chlorophenoxy)-2-methylpropionate, as principal active ingredient, in combination with a pharmaceutically acceptable carrier. Total serum lipids and serum cholesterol levels are significantly reduced.
    Type: Grant
    Filed: March 8, 1978
    Date of Patent: December 18, 1979
    Assignee: Laboratoires Sarget
    Inventors: Francois Fauran, Claude Feniou, Jacqueline Mosser, Gisele Prat
  • Patent number: 4146615
    Abstract: A plant extract rich in triterpenic constituents obtained from chrysanthellum and containing as principle component a triterpenic saponin derivative of echinocystic acid whose glycoside contains rhamnose, glucose and xylose may be prepared by extraction of chrysanthellum plants. The extract has been shown to have pharmacological activity, especially analgesic, anti-inflammatory, capillaroprotective and anti-ulcer activity.
    Type: Grant
    Filed: January 19, 1978
    Date of Patent: March 27, 1979
    Assignee: Laboratoires Sarget
    Inventors: Francois Fauran, Gisele Prat, Annie Thibault, Claude Andre-Mouries, Henri Combier